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The map label for this gene is ccmA

Identifier: 66046622

GI number: 66046622

Start: 4050761

End: 4051408

Strand: Reverse

Name: ccmA

Synonym: Psyr_3393

Alternate gene names: 66046622

Gene position: 4051408-4050761 (Counterclockwise)

Preceding gene: 66046625

Following gene: 66046621

Centisome position: 66.49

GC content: 64.81

Gene sequence:

>648_bases
ATGATCCCAGCCACCCCATTTTTGCAAGCGACGGCTCTGGCGTGTGAGCGGGACGGGCGGATGCTGTTCGAAAACCTCGA
TCTTCACCTGCACACAGGCGACATGCTGCAGATCAGCGGTCCCAACGGCTGCGGCAAGACCAGCCTGCTGCGCCTGCTGT
GCGGGCTGATGCAGCCAACGGCCGGGCAAATCCTGCTCGACGCGCAGCCACTGGGCCGGCAGCCCGCCGCACCGGGCCGC
AAACCGTTGTGGATCGGTCATGCGCCAGCGATCAAGGATGTGCTGACGCCACTGGAAAACCTGTCCTGGCTCAGTGCACT
TCACCAGCCGGACGGTGCCGATGCCGATACCATTGCCACCGCGCTCGATGCGGTCGGGCTGGCAGGTTTCGAGGATGTGC
CCTGTCACACCTTGTCGGCCGGGCAGCAGCGTCGCGTCGCGCTGGCACGTCTGTATCTGCCGGGCCCGCCACTCTGGCTG
CTCGACGAGCCGTTTACCGCGCTCGACCGCCAAGGCATCGAGCAACTGGAGAAACACCTCGCCGAGCACTGTGAACACGG
CGGCATGATTGTCATGACCACTCACCACAGCCTGAACCGCCTGCCTGCGGGCTATCGGGACCTCGACCTGGGGCAATGGT
CAGCATGA

Upstream 100 bases:

>100_bases
TCTTCATGTAACGGCCGTATCAACCCCGACTTGAACCGCGTTTTACTCCGTATGTGTCTGTTTTGGCACATTTCGCGACG
CAAAACACTGGAAACGCCCG

Downstream 100 bases:

>100_bases
GCAATGTGTTTGTCCTGCTGATGCTTCGTGAGGTGCGGCTGCTGGCGAGGCGTCCGGCAGAGCTGACCAACCCGCTGGTG
TTCTTTGCGATCGTGGTCGC

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIPATPFLQATALACERDGRMLFENLDLHLHTGDMLQISGPNGCGKTSLLRLLCGLMQPTAGQILLDAQPLGRQPAAPGR
KPLWIGHAPAIKDVLTPLENLSWLSALHQPDGADADTIATALDAVGLAGFEDVPCHTLSAGQQRRVALARLYLPGPPLWL
LDEPFTALDRQGIEQLEKHLAEHCEHGGMIVMTTHHSLNRLPAGYRDLDLGQWSA

Sequences:

>Translated_215_residues
MIPATPFLQATALACERDGRMLFENLDLHLHTGDMLQISGPNGCGKTSLLRLLCGLMQPTAGQILLDAQPLGRQPAAPGR
KPLWIGHAPAIKDVLTPLENLSWLSALHQPDGADADTIATALDAVGLAGFEDVPCHTLSAGQQRRVALARLYLPGPPLWL
LDEPFTALDRQGIEQLEKHLAEHCEHGGMIVMTTHHSLNRLPAGYRDLDLGQWSA
>Mature_215_residues
MIPATPFLQATALACERDGRMLFENLDLHLHTGDMLQISGPNGCGKTSLLRLLCGLMQPTAGQILLDAQPLGRQPAAPGR
KPLWIGHAPAIKDVLTPLENLSWLSALHQPDGADADTIATALDAVGLAGFEDVPCHTLSAGQQRRVALARLYLPGPPLWL
LDEPFTALDRQGIEQLEKHLAEHCEHGGMIVMTTHHSLNRLPAGYRDLDLGQWSA

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27436953, Length=194, Percent_Identity=29.8969072164948, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI150417984, Length=173, Percent_Identity=29.4797687861272, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27477115, Length=188, Percent_Identity=28.7234042553192, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI6005701, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI9665248, Length=196, Percent_Identity=31.6326530612245, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI27881501, Length=175, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=175, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI153792144, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87082064, Length=206, Percent_Identity=49.5145631067961, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI87081791, Length=194, Percent_Identity=34.020618556701, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787370, Length=193, Percent_Identity=34.1968911917098, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081709, Length=182, Percent_Identity=31.8681318681319, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789864, Length=227, Percent_Identity=28.6343612334802, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788761, Length=180, Percent_Identity=33.8888888888889, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786563, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790467, Length=184, Percent_Identity=28.804347826087, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1788053, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081782, Length=195, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789593, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788225, Length=200, Percent_Identity=29, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87081834, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786803, Length=183, Percent_Identity=30.0546448087432, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367384, Length=226, Percent_Identity=28.7610619469027, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789032, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786703, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787041, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082267, Length=165, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=201, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786345, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994943, Length=193, Percent_Identity=21.7616580310881, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788165, Length=170, Percent_Identity=31.7647058823529, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=192, Percent_Identity=30.2083333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787758, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787112, Length=183, Percent_Identity=30.6010928961749, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=183, Percent_Identity=27.8688524590164, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788002, Length=174, Percent_Identity=31.0344827586207, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=181, Percent_Identity=32.5966850828729, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362751, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650855, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650853, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581383, Length=184, Percent_Identity=27.1739130434783, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24581385, Length=184, Percent_Identity=27.1739130434783, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_PSEU2 (Q4ZQZ7)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_236463.1
- ProteinModelPortal:   Q4ZQZ7
- SMR:   Q4ZQZ7
- STRING:   Q4ZQZ7
- GeneID:   3368920
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_3393
- NMPDR:   fig|205918.4.peg.3688
- eggNOG:   COG4133
- HOGENOM:   HBG758042
- OMA:   ARLWHND
- ProtClustDB:   PRK13538
- BioCyc:   PSYR205918:PSYR_3393-MONOMER
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 23259; Mature: 23259

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPATPFLQATALACERDGRMLFENLDLHLHTGDMLQISGPNGCGKTSLLRLLCGLMQPT
CCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCC
AGQILLDAQPLGRQPAAPGRKPLWIGHAPAIKDVLTPLENLSWLSALHQPDGADADTIAT
CCEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALDAVGLAGFEDVPCHTLSAGQQRRVALARLYLPGPPLWLLDEPFTALDRQGIEQLEKHL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHH
AEHCEHGGMIVMTTHHSLNRLPAGYRDLDLGQWSA
HHHHCCCCEEEEEECCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPATPFLQATALACERDGRMLFENLDLHLHTGDMLQISGPNGCGKTSLLRLLCGLMQPT
CCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCC
AGQILLDAQPLGRQPAAPGRKPLWIGHAPAIKDVLTPLENLSWLSALHQPDGADADTIAT
CCEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALDAVGLAGFEDVPCHTLSAGQQRRVALARLYLPGPPLWLLDEPFTALDRQGIEQLEKHL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHH
AEHCEHGGMIVMTTHHSLNRLPAGYRDLDLGQWSA
HHHHCCCCEEEEEECCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA