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The map label for this gene is aaeA [H]

Identifier: 66046609

GI number: 66046609

Start: 4038965

End: 4039849

Strand: Direct

Name: aaeA [H]

Synonym: Psyr_3380

Alternate gene names: 66046609

Gene position: 4038965-4039849 (Clockwise)

Preceding gene: 66046608

Following gene: 66046610

Centisome position: 66.28

GC content: 62.71

Gene sequence:

>885_bases
ATGAAAAAACCGATACTGACACTGGGCCGCGTGGTCCTGACCCTGCTGGTTGTCACCCTGGCCGCCGTGGTCGTATGGCG
CATGGTGATGTATTACATGTATGCGCCGTGGACGCGCGACGGGCATATCCGCGCCGATGTCGTGCAGATCGCTCCGGACG
TGTCCGGACTGATCCAGAAGGTTGAAGTCACTGACAACCAGCCCGTGCACAAGGGCCAGATCCTGTTCACCATCGATCAG
GACCGTTTCCGTCTGGCACTGCGCCAGGCGCAGGCGACGGTCGCCGAACGTCAGGAAACCTGGGAACAGGCGCGCCGCGA
GAACAAGCGTAACCGTGGTCTGGGCAATCTGGTCGCCCGCGAGCAACTGGAAGAAAGCCAGTCACGCGAAGCTCGGGCCC
TTTCGGCGCTGGGCGAATCAAAGGTTGCAGTGGATGCCGCACAGTTGAACCTGGATCGCTCGGTGATCCGCAGTCCGGTG
GACGGCTACCTCAACGACCGCGCGCCCCGCGAACATGAGTTCGTCACTGCCGGGCACCCGGTGCTTTCGGTGGTCGATTC
GACGTCGTTCCACATCGATGGCTATTTCGAGGAAACCAAGCTCGATGGGATTCATGTCGGCCAGGGCGTCGACATCCGCG
TCATCGGCGACAGCGCGCGTCTGACCGGCCATGTGGTGAGCATCGTTGCCGGTATCGAAGACCGCGACCGCAGCAGCGGC
TCGAACCTGCTGCCCAACGTCAATCCGGCCTTCAGCTGGGTGCGTCTGGCGCAGCGGATTCCGGTGCGGATCGCCTTCGA
TGATGTGCCTGCCGACTTCCGCATGATTGCCGGGCGTACCGCGACGGTGTCGATCATCGACGACACCCAGGAGCGCAGCC
GATGA

Upstream 100 bases:

>100_bases
CCCACTTCTACCGTCTGGTCTGGCACCGGGCTTTGTTCAACGTAGGTCTATACGCTTTGTTGCTCGGCGCCGTGGATACT
CTAAGTCGATACCTGATGAC

Downstream 100 bases:

>100_bases
AACCTGCTTTACGCGTGGCCGCTCTCGGCTTTACCGCCGTGCTGTCAGCCTGCCAGATGGTCGGCCCGGATTACCAGGTG
CCCAAGGACGGCGCGATCAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKKPILTLGRVVLTLLVVTLAAVVVWRMVMYYMYAPWTRDGHIRADVVQIAPDVSGLIQKVEVTDNQPVHKGQILFTIDQ
DRFRLALRQAQATVAERQETWEQARRENKRNRGLGNLVAREQLEESQSREARALSALGESKVAVDAAQLNLDRSVIRSPV
DGYLNDRAPREHEFVTAGHPVLSVVDSTSFHIDGYFEETKLDGIHVGQGVDIRVIGDSARLTGHVVSIVAGIEDRDRSSG
SNLLPNVNPAFSWVRLAQRIPVRIAFDDVPADFRMIAGRTATVSIIDDTQERSR

Sequences:

>Translated_294_residues
MKKPILTLGRVVLTLLVVTLAAVVVWRMVMYYMYAPWTRDGHIRADVVQIAPDVSGLIQKVEVTDNQPVHKGQILFTIDQ
DRFRLALRQAQATVAERQETWEQARRENKRNRGLGNLVAREQLEESQSREARALSALGESKVAVDAAQLNLDRSVIRSPV
DGYLNDRAPREHEFVTAGHPVLSVVDSTSFHIDGYFEETKLDGIHVGQGVDIRVIGDSARLTGHVVSIVAGIEDRDRSSG
SNLLPNVNPAFSWVRLAQRIPVRIAFDDVPADFRMIAGRTATVSIIDDTQERSR
>Mature_294_residues
MKKPILTLGRVVLTLLVVTLAAVVVWRMVMYYMYAPWTRDGHIRADVVQIAPDVSGLIQKVEVTDNQPVHKGQILFTIDQ
DRFRLALRQAQATVAERQETWEQARRENKRNRGLGNLVAREQLEESQSREARALSALGESKVAVDAAQLNLDRSVIRSPV
DGYLNDRAPREHEFVTAGHPVLSVVDSTSFHIDGYFEETKLDGIHVGQGVDIRVIGDSARLTGHVVSIVAGIEDRDRSSG
SNLLPNVNPAFSWVRLAQRIPVRIAFDDVPADFRMIAGRTATVSIIDDTQERSR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=293, Percent_Identity=39.5904436860068, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081951, Length=273, Percent_Identity=38.8278388278388, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1790519, Length=316, Percent_Identity=28.7974683544304, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789041, Length=303, Percent_Identity=26.0726072607261, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788711, Length=313, Percent_Identity=24.6006389776358, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082036, Length=154, Percent_Identity=30.5194805194805, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 32823; Mature: 32823

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPILTLGRVVLTLLVVTLAAVVVWRMVMYYMYAPWTRDGHIRADVVQIAPDVSGLIQK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHEECCCCHHHHHHH
VEVTDNQPVHKGQILFTIDQDRFRLALRQAQATVAERQETWEQARRENKRNRGLGNLVAR
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
EQLEESQSREARALSALGESKVAVDAAQLNLDRSVIRSPVDGYLNDRAPREHEFVTAGHP
HHHHHHHHHHHHHHHHHCCCHHEEEHHHHCCCHHHHCCCHHHHHCCCCCCCCCEEECCCH
VLSVVDSTSFHIDGYFEETKLDGIHVGQGVDIRVIGDSARLTGHVVSIVAGIEDRDRSSG
HHEEECCCEEEEECEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
SNLLPNVNPAFSWVRLAQRIPVRIAFDDVPADFRMIAGRTATVSIIDDTQERSR
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHCCCCEEEEEEECCHHHCC
>Mature Secondary Structure
MKKPILTLGRVVLTLLVVTLAAVVVWRMVMYYMYAPWTRDGHIRADVVQIAPDVSGLIQK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHEECCCCHHHHHHH
VEVTDNQPVHKGQILFTIDQDRFRLALRQAQATVAERQETWEQARRENKRNRGLGNLVAR
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
EQLEESQSREARALSALGESKVAVDAAQLNLDRSVIRSPVDGYLNDRAPREHEFVTAGHP
HHHHHHHHHHHHHHHHHCCCHHEEEHHHHCCCHHHHCCCHHHHHCCCCCCCCCEEECCCH
VLSVVDSTSFHIDGYFEETKLDGIHVGQGVDIRVIGDSARLTGHVVSIVAGIEDRDRSSG
HHEEECCCEEEEECEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
SNLLPNVNPAFSWVRLAQRIPVRIAFDDVPADFRMIAGRTATVSIIDDTQERSR
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHCCCCEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA