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The map label for this gene is aaeB [H]

Identifier: 66046607

GI number: 66046607

Start: 4036675

End: 4038762

Strand: Direct

Name: aaeB [H]

Synonym: Psyr_3378

Alternate gene names: 66046607

Gene position: 4036675-4038762 (Clockwise)

Preceding gene: 66046606

Following gene: 66046608

Centisome position: 66.24

GC content: 62.36

Gene sequence:

>2088_bases
TTGAACGGATTTTTCTCCAGCGTTCCACCTGCACGCGACTGGTTCTACGGTGTGCGCACCTTCGGCGCATCAATGCTGGC
GCTGTACATCGCATTGTTGATGGAAATGCCCCGCCCCTACTGGGCAATGGCCACGGTGTACATCGTCTCCAGCCCCTTCG
TCGGCCCGACCAGCTCCAAGGCCCTGTACAGAGCCGCCGGAACCCTGGCCGGTGCCGCAGCATCGGTGGTGCTGGTGCCC
ATGTTCGTGCAGACGCCCTTGTTGCTGGCCATCGTGGTCGGGCTGTGGACGGGCACCCTGTTGTTTCTGTCCCTGCACTT
GCGCACCGCCAACAGCTACGCATTGATGCTGGCCGGCTACACCATGCCGCTGATTTCGCTGCCGGTGGTCGACAACCCGC
AGGCTGTTTTCGACATCGCGGTGTCGCGTACCGAAGAGATTTTTCTCGGCATCATCTGCGCCGCTGTCGTGGGTGCGATG
TTCTGGCCCAGACGCCTGGCACCGGTGTTTCAGGCCACCACGGAAAAGTGGTTCAGTGACGCCGCGACTTACAGTCAGCG
CTTTATCAGCCGCACCTGTCAGCCCGAAGAAATCGGCACACTGCGAAATTCGATGGTCGGCAGCTTCAACTCGCTGGAAA
TGATGATCGGCCAGTTGAGCCACGAAGGCGCCCGCAAGCAAACCGTGCGCAATGCCAATGAACTGCGCGGCCGGATGATC
CACCTCTTGCCGGTCATTGATGCGCTGGATGACGCGCTGTGGGCGCTGGAGCGACGCACACCCGAGCTGCTGGCCAGCGT
CAGACCCTTATTGCACAAGACTTGCGACTGGCTCGAAAGCACTGCCGACGGGCCGCAGGTGGAGCAATGGCAGCAGCTGC
ATCGTGATCTGCAGAGCCTGCAACCGGACTCCGCGCAACTGGACGATCGCGATCAACTGCTGCTCTCCAATACGCTGTTC
AGGCTGGGCGAATGGATCGACCTGTGGCTGGATTGCCGAACCCTGCAATACGCGATCAAGACCGACGACCAGTCACAGTG
GCGCGCGGTCTACCGCCACTGGCGCCTGGGCCGGCTTACCCCGTTTCTCGACCGCGGTCTGATGCTCTATTCGGTGACCT
CGACAGTACTGGCGATCATCGCCGCGTCGGTGTTGTGGATTCTGCTCGGCTGGAAAGACGGCGCAAGTGCCGTGGCACTG
GCGGCGGTGTCGTGCAGCTTCTTCGCCGCCATGGACGACCCTGCTCCGCAAATCTACCGGTTCTTTTTCTGGACCCTGCT
CTCGGTGGTGTTCGCCAGCCTGTACCTGTTTGTGGTGCTGCCCAACCTGCATGACTTCCCGATGCTGGTGCTGGCCTTTG
CCGTGCCGTTCATTTGCGTCGGCACCCTGACCGTGCAGCCGCGCTTCTTTCTCGGCACGCTGCTGACCATCGTCAACACC
TCGTCGTTCATCAGTATCCAGAGCGCTTATGACGCGGACTTCATGAACTTCCTCAACGCCAACCTGGCGGGTCCTGTCGG
ACTGCTGTTCGCCTTCATCTGGACCCTGGTGTTCCGCCCGTTCGGCGTCGAACTGGCGGTCAAGCGCCTGACCCGGTTCA
GCTGGCGTGACATCGCCAGTCTCAGTGAAAACGCGTCTCTGGCCGAGCATCGGCGCATGGGCGTGCAAATGCTCGACCGC
CTGATGCAACAACTGCCGCGCCTGACGCTCACCGCCCAGGACACCGGGATTGCCCTGCGTGAACTGCGCGTCGCGCTGAA
CATGCTCGACCTGCTGGCCTACACCCGCCGTGCCACGCCTGCGGCTCAGGTGCTGTTGCGTCAGGTGATCGACGAAGTCA
GCGGCTATTTCAAACTGTGCCGCAAGGCCGGTGAACGGCTACCCGCGCCCAGAGGCCTGCTGATGGCCATGGACCGCGCA
CGCCGTTCACTGACCGATCAGGAGATGGGCGACAACCCGGCCCGACTGCACCTTCTGCATGCCCTGAGTGGCCTGCGCCT
GGCTCTGCTCCCGGGGGTCGAGATCGTCACCGTGGGCGGGGAACTGACCGAGCAACTGCCGCATAACATCGATGGAGCGC
CCCTGTGA

Upstream 100 bases:

>100_bases
CCGAAGTGCTGCAAGGGCTGCAACCTGCCGATCTGGAAGCCACGTTACGGGTGTTACAGGCGTTTGCCGATGCGGCGCAG
CGCGAACACGGGGGCCAGGC

Downstream 100 bases:

>100_bases
TCGGTGATCTGGATATCAGCGGGATCTTCATCCCCACGTTCCTGGCGATGATGGGCATCGCCTATCTGCTGTTTCTGGTC
GTGCACGCGGTGCTGTCGCG

Product: fusaric acid resistance protein region

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNGFFSSVPPARDWFYGVRTFGASMLALYIALLMEMPRPYWAMATVYIVSSPFVGPTSSKALYRAAGTLAGAAASVVLVP
MFVQTPLLLAIVVGLWTGTLLFLSLHLRTANSYALMLAGYTMPLISLPVVDNPQAVFDIAVSRTEEIFLGIICAAVVGAM
FWPRRLAPVFQATTEKWFSDAATYSQRFISRTCQPEEIGTLRNSMVGSFNSLEMMIGQLSHEGARKQTVRNANELRGRMI
HLLPVIDALDDALWALERRTPELLASVRPLLHKTCDWLESTADGPQVEQWQQLHRDLQSLQPDSAQLDDRDQLLLSNTLF
RLGEWIDLWLDCRTLQYAIKTDDQSQWRAVYRHWRLGRLTPFLDRGLMLYSVTSTVLAIIAASVLWILLGWKDGASAVAL
AAVSCSFFAAMDDPAPQIYRFFFWTLLSVVFASLYLFVVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFFLGTLLTIVNT
SSFISIQSAYDADFMNFLNANLAGPVGLLFAFIWTLVFRPFGVELAVKRLTRFSWRDIASLSENASLAEHRRMGVQMLDR
LMQQLPRLTLTAQDTGIALRELRVALNMLDLLAYTRRATPAAQVLLRQVIDEVSGYFKLCRKAGERLPAPRGLLMAMDRA
RRSLTDQEMGDNPARLHLLHALSGLRLALLPGVEIVTVGGELTEQLPHNIDGAPL

Sequences:

>Translated_695_residues
MNGFFSSVPPARDWFYGVRTFGASMLALYIALLMEMPRPYWAMATVYIVSSPFVGPTSSKALYRAAGTLAGAAASVVLVP
MFVQTPLLLAIVVGLWTGTLLFLSLHLRTANSYALMLAGYTMPLISLPVVDNPQAVFDIAVSRTEEIFLGIICAAVVGAM
FWPRRLAPVFQATTEKWFSDAATYSQRFISRTCQPEEIGTLRNSMVGSFNSLEMMIGQLSHEGARKQTVRNANELRGRMI
HLLPVIDALDDALWALERRTPELLASVRPLLHKTCDWLESTADGPQVEQWQQLHRDLQSLQPDSAQLDDRDQLLLSNTLF
RLGEWIDLWLDCRTLQYAIKTDDQSQWRAVYRHWRLGRLTPFLDRGLMLYSVTSTVLAIIAASVLWILLGWKDGASAVAL
AAVSCSFFAAMDDPAPQIYRFFFWTLLSVVFASLYLFVVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFFLGTLLTIVNT
SSFISIQSAYDADFMNFLNANLAGPVGLLFAFIWTLVFRPFGVELAVKRLTRFSWRDIASLSENASLAEHRRMGVQMLDR
LMQQLPRLTLTAQDTGIALRELRVALNMLDLLAYTRRATPAAQVLLRQVIDEVSGYFKLCRKAGERLPAPRGLLMAMDRA
RRSLTDQEMGDNPARLHLLHALSGLRLALLPGVEIVTVGGELTEQLPHNIDGAPL
>Mature_695_residues
MNGFFSSVPPARDWFYGVRTFGASMLALYIALLMEMPRPYWAMATVYIVSSPFVGPTSSKALYRAAGTLAGAAASVVLVP
MFVQTPLLLAIVVGLWTGTLLFLSLHLRTANSYALMLAGYTMPLISLPVVDNPQAVFDIAVSRTEEIFLGIICAAVVGAM
FWPRRLAPVFQATTEKWFSDAATYSQRFISRTCQPEEIGTLRNSMVGSFNSLEMMIGQLSHEGARKQTVRNANELRGRMI
HLLPVIDALDDALWALERRTPELLASVRPLLHKTCDWLESTADGPQVEQWQQLHRDLQSLQPDSAQLDDRDQLLLSNTLF
RLGEWIDLWLDCRTLQYAIKTDDQSQWRAVYRHWRLGRLTPFLDRGLMLYSVTSTVLAIIAASVLWILLGWKDGASAVAL
AAVSCSFFAAMDDPAPQIYRFFFWTLLSVVFASLYLFVVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFFLGTLLTIVNT
SSFISIQSAYDADFMNFLNANLAGPVGLLFAFIWTLVFRPFGVELAVKRLTRFSWRDIASLSENASLAEHRRMGVQMLDR
LMQQLPRLTLTAQDTGIALRELRVALNMLDLLAYTRRATPAAQVLLRQVIDEVSGYFKLCRKAGERLPAPRGLLMAMDRA
RRSLTDQEMGDNPARLHLLHALSGLRLALLPGVEIVTVGGELTEQLPHNIDGAPL

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=641, Percent_Identity=24.4929797191888, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1787933, Length=560, Percent_Identity=26.9642857142857, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 77611; Mature: 77611

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFFSSVPPARDWFYGVRTFGASMLALYIALLMEMPRPYWAMATVYIVSSPFVGPTSSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCH
ALYRAAGTLAGAAASVVLVPMFVQTPLLLAIVVGLWTGTLLFLSLHLRTANSYALMLAGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TMPLISLPVVDNPQAVFDIAVSRTEEIFLGIICAAVVGAMFWPRRLAPVFQATTEKWFSD
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATYSQRFISRTCQPEEIGTLRNSMVGSFNSLEMMIGQLSHEGARKQTVRNANELRGRMI
HHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHH
HLLPVIDALDDALWALERRTPELLASVRPLLHKTCDWLESTADGPQVEQWQQLHRDLQSL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
QPDSAQLDDRDQLLLSNTLFRLGEWIDLWLDCRTLQYAIKTDDQSQWRAVYRHWRLGRLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
PFLDRGLMLYSVTSTVLAIIAASVLWILLGWKDGASAVALAAVSCSFFAAMDDPAPQIYR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FFFWTLLSVVFASLYLFVVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFFLGTLLTIVNT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SSFISIQSAYDADFMNFLNANLAGPVGLLFAFIWTLVFRPFGVELAVKRLTRFSWRDIAS
CHHEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSENASLAEHRRMGVQMLDRLMQQLPRLTLTAQDTGIALRELRVALNMLDLLAYTRRATP
HHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCH
AAQVLLRQVIDEVSGYFKLCRKAGERLPAPRGLLMAMDRARRSLTDQEMGDNPARLHLLH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHH
ALSGLRLALLPGVEIVTVGGELTEQLPHNIDGAPL
HHHCCCEEECCCCEEEEECHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNGFFSSVPPARDWFYGVRTFGASMLALYIALLMEMPRPYWAMATVYIVSSPFVGPTSSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCH
ALYRAAGTLAGAAASVVLVPMFVQTPLLLAIVVGLWTGTLLFLSLHLRTANSYALMLAGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TMPLISLPVVDNPQAVFDIAVSRTEEIFLGIICAAVVGAMFWPRRLAPVFQATTEKWFSD
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATYSQRFISRTCQPEEIGTLRNSMVGSFNSLEMMIGQLSHEGARKQTVRNANELRGRMI
HHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHH
HLLPVIDALDDALWALERRTPELLASVRPLLHKTCDWLESTADGPQVEQWQQLHRDLQSL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
QPDSAQLDDRDQLLLSNTLFRLGEWIDLWLDCRTLQYAIKTDDQSQWRAVYRHWRLGRLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
PFLDRGLMLYSVTSTVLAIIAASVLWILLGWKDGASAVALAAVSCSFFAAMDDPAPQIYR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
FFFWTLLSVVFASLYLFVVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFFLGTLLTIVNT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SSFISIQSAYDADFMNFLNANLAGPVGLLFAFIWTLVFRPFGVELAVKRLTRFSWRDIAS
CHHEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSENASLAEHRRMGVQMLDRLMQQLPRLTLTAQDTGIALRELRVALNMLDLLAYTRRATP
HHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCH
AAQVLLRQVIDEVSGYFKLCRKAGERLPAPRGLLMAMDRARRSLTDQEMGDNPARLHLLH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHH
ALSGLRLALLPGVEIVTVGGELTEQLPHNIDGAPL
HHHCCCEEECCCCEEEEECHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA