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The map label for this gene is aldH [H]

Identifier: 66046386

GI number: 66046386

Start: 3783012

End: 3784595

Strand: Direct

Name: aldH [H]

Synonym: Psyr_3157

Alternate gene names: 66046386

Gene position: 3783012-3784595 (Clockwise)

Preceding gene: 66046385

Following gene: 66046387

Centisome position: 62.08

GC content: 62.63

Gene sequence:

>1584_bases
ATGCCTAACATTCTCGGCCAGAACTTCATCGCTGGCGGCCGCAGCGCTTTGGGCCAGAGCCTGCAAAAAAGCCTGGATGC
CACCACCGGTGAAGAGCTGCCTTACAGTTTTCATCAGGCCACCGACGGCGAAATCGACGCTGCGGCACTGGCTGCCAAGG
CTGCGTTTGCGGAATTTCGTCAGCTGAGCCCGGCCCGCCGCGCCGACTTCCTCGACGCCATTGCCGATGAACTTGACCAG
CTGGGTGATGACTTCGTCGCCATCGTCTGCCAGGAAACCGCCCTGCCCCAGGCGCGAATTCAAGGTGAGCGCGGTCGCAC
CAGTGGCCAGATGCGCCTGTTTTCCAAAGTTCTGCGTCGCGGTGATTTTGTTGGTGCACGTATCGACCTGGCACTGCCGG
ATCGCAAGCCGCTGCCACGCGTCGACCTGCGCCAATACCGTATCGGTGTCGGCCCGGTTGCGGTGTTCGGAGCGAGCAAC
TTCCCGCTGGCGTTTTCCACTGCCGGTGGTGATACCGCGGCGGCCTTGGCCGCCGGTTGCCCGGTGGTGTTCAAGGCGCA
CAGCGGTCACATGGCGACCGCCGATCTGGTGGCGAGCGCCATCATTCGCGCTGCCGAACGTACGCAGATGCCCAAAGGCG
TGTTCAACATGATCTTCGGCAACGGCGTTGGCGAAGGTCTGGTCAAGCACCCGGCCATCCAGGCCGTCGGCTTTACCGGT
TCGCTGAACGGCGGCAACGCACTGTGCAAAATGGCTGCCGAACGTCCGCAACCGATTCCGGTATTTGCCGAGATGTCGAG
CATCAACCCGGTCGTGCTGCTGCCAGAAGCCTTGCAGGCTCGCGGTGAAACCGTGGCCAAGGAGCTTGCGGGCTCGGTGG
TGATGGGTGCCGGTCAGTTTTGCACCAACCCGGGCGTGGTCATCGGCCTGCGCTCACCGGCGTTCTCAAAATTCGTTGAG
CATCTGACCGAACAGATGGGCAGTCAGGCTCCGCAGACCATGCTTAACGCGGGCGGCCTGCGCAGTTACAACAAAGGTGT
GGAACACCTGATGGCGCACCCTGGCGTGACGCATCTGGCCGGCAAGCCACAGGAAGGCAAGCAGGCTCAGGCGCAGCTAT
TCAAGGCTGACGTCAGCCTGCTGCTGAACGGTGATCAGTTGCTGCAAGAGGAAGTCTTCGGCCCGACCACGCTGCTGATC
GAAGTCGCTGACGATGCGCAGTTGAAGGACGCGCTGCAAGCCTTGCGTGGTCAGCTGACTGCGACCGTGATCGGTGAGCC
CGCGGACTTGAGCAACTACAGCTGGCTGCAACCGGTTCTCGAAGAGAGAGTCGGGCGCATTCTGTTCAACGGCTACCCGA
CCGGTGTCGAGGTCTGCGAGGCCATGGTTCACGGCGGCCCATACCCGGCCACCTCGGACGCACGCGGTACCTCGGTGGGC
ACCCTGGCCATCGACCGCTTCCTGCGCCCGGTCTGCTATCAGAACCTGGCGGACAGCCAGTTGCCACCTGCGTTGCAGAA
CGCCAACCCGTTGGGCCTGCGTCGTCTGGTCAATGGTGAATGGAGTGATCAGCCTGTCGCGTAA

Upstream 100 bases:

>100_bases
CATCACTGACAATCTGTAAAGCAACTCGGCAACCCATAAGGAGCGCCGGTCCGGATACTTTCCCTGCCGACCTCCAACCT
CAAAACAACAGGAGATACCG

Downstream 100 bases:

>100_bases
CGGCCACCGGCTGGATCCGCAACACAGCAGCGCGACCTGATGAGGGTCGCGCTTTTTTTTGGAAAATATTTCTTTTTTGT
GCCCGAAGTCGCTTATAGCG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MPNILGQNFIAGGRSALGQSLQKSLDATTGEELPYSFHQATDGEIDAAALAAKAAFAEFRQLSPARRADFLDAIADELDQ
LGDDFVAIVCQETALPQARIQGERGRTSGQMRLFSKVLRRGDFVGARIDLALPDRKPLPRVDLRQYRIGVGPVAVFGASN
FPLAFSTAGGDTAAALAAGCPVVFKAHSGHMATADLVASAIIRAAERTQMPKGVFNMIFGNGVGEGLVKHPAIQAVGFTG
SLNGGNALCKMAAERPQPIPVFAEMSSINPVVLLPEALQARGETVAKELAGSVVMGAGQFCTNPGVVIGLRSPAFSKFVE
HLTEQMGSQAPQTMLNAGGLRSYNKGVEHLMAHPGVTHLAGKPQEGKQAQAQLFKADVSLLLNGDQLLQEEVFGPTTLLI
EVADDAQLKDALQALRGQLTATVIGEPADLSNYSWLQPVLEERVGRILFNGYPTGVEVCEAMVHGGPYPATSDARGTSVG
TLAIDRFLRPVCYQNLADSQLPPALQNANPLGLRRLVNGEWSDQPVA

Sequences:

>Translated_527_residues
MPNILGQNFIAGGRSALGQSLQKSLDATTGEELPYSFHQATDGEIDAAALAAKAAFAEFRQLSPARRADFLDAIADELDQ
LGDDFVAIVCQETALPQARIQGERGRTSGQMRLFSKVLRRGDFVGARIDLALPDRKPLPRVDLRQYRIGVGPVAVFGASN
FPLAFSTAGGDTAAALAAGCPVVFKAHSGHMATADLVASAIIRAAERTQMPKGVFNMIFGNGVGEGLVKHPAIQAVGFTG
SLNGGNALCKMAAERPQPIPVFAEMSSINPVVLLPEALQARGETVAKELAGSVVMGAGQFCTNPGVVIGLRSPAFSKFVE
HLTEQMGSQAPQTMLNAGGLRSYNKGVEHLMAHPGVTHLAGKPQEGKQAQAQLFKADVSLLLNGDQLLQEEVFGPTTLLI
EVADDAQLKDALQALRGQLTATVIGEPADLSNYSWLQPVLEERVGRILFNGYPTGVEVCEAMVHGGPYPATSDARGTSVG
TLAIDRFLRPVCYQNLADSQLPPALQNANPLGLRRLVNGEWSDQPVA
>Mature_526_residues
PNILGQNFIAGGRSALGQSLQKSLDATTGEELPYSFHQATDGEIDAAALAAKAAFAEFRQLSPARRADFLDAIADELDQL
GDDFVAIVCQETALPQARIQGERGRTSGQMRLFSKVLRRGDFVGARIDLALPDRKPLPRVDLRQYRIGVGPVAVFGASNF
PLAFSTAGGDTAAALAAGCPVVFKAHSGHMATADLVASAIIRAAERTQMPKGVFNMIFGNGVGEGLVKHPAIQAVGFTGS
LNGGNALCKMAAERPQPIPVFAEMSSINPVVLLPEALQARGETVAKELAGSVVMGAGQFCTNPGVVIGLRSPAFSKFVEH
LTEQMGSQAPQTMLNAGGLRSYNKGVEHLMAHPGVTHLAGKPQEGKQAQAQLFKADVSLLLNGDQLLQEEVFGPTTLLIE
VADDAQLKDALQALRGQLTATVIGEPADLSNYSWLQPVLEERVGRILFNGYPTGVEVCEAMVHGGPYPATSDARGTSVGT
LAIDRFLRPVCYQNLADSQLPPALQNANPLGLRRLVNGEWSDQPVA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=440, Percent_Identity=23.8636363636364, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI25952152, Length=278, Percent_Identity=27.3381294964029, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4507229, Length=368, Percent_Identity=26.9021739130435, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI25777721, Length=377, Percent_Identity=26.2599469496021, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081896, Length=425, Percent_Identity=26.3529411764706, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787684, Length=378, Percent_Identity=25.1322751322751, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788042, Length=383, Percent_Identity=25.8485639686684, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789015, Length=285, Percent_Identity=27.3684210526316, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787250, Length=270, Percent_Identity=28.5185185185185, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25143874, Length=326, Percent_Identity=25.4601226993865, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25143876, Length=326, Percent_Identity=25.4601226993865, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=461, Percent_Identity=23.644251626898, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319478, Length=289, Percent_Identity=26.643598615917, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362580, Length=392, Percent_Identity=26.2755102040816, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI62472918, Length=392, Percent_Identity=26.2755102040816, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI62472926, Length=392, Percent_Identity=26.2755102040816, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI62472936, Length=392, Percent_Identity=26.2755102040816, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356737, Length=392, Percent_Identity=26.2755102040816, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55760; Mature: 55629

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNILGQNFIAGGRSALGQSLQKSLDATTGEELPYSFHQATDGEIDAAALAAKAAFAEFR
CCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHH
QLSPARRADFLDAIADELDQLGDDFVAIVCQETALPQARIQGERGRTSGQMRLFSKVLRR
HCCHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCCCHHHHCCCCCCCCHHHHHHHHHHHC
GDFVGARIDLALPDRKPLPRVDLRQYRIGVGPVAVFGASNFPLAFSTAGGDTAAALAAGC
CCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCC
PVVFKAHSGHMATADLVASAIIRAAERTQMPKGVFNMIFGNGVGEGLVKHPAIQAVGFTG
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCEEEECCC
SLNGGNALCKMAAERPQPIPVFAEMSSINPVVLLPEALQARGETVAKELAGSVVMGAGQF
CCCCCHHHHHHHHCCCCCCEEEEHHCCCCCEEECCHHHHHHHHHHHHHHHCHHEECCCCC
CTNPGVVIGLRSPAFSKFVEHLTEQMGSQAPQTMLNAGGLRSYNKGVEHLMAHPGVTHLA
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHCC
GKPQEGKQAQAQLFKADVSLLLNGDQLLQEEVFGPTTLLIEVADDAQLKDALQALRGQLT
CCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCEE
ATVIGEPADLSNYSWLQPVLEERVGRILFNGYPTGVEVCEAMVHGGPYPATSDARGTSVG
EEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
TLAIDRFLRPVCYQNLADSQLPPALQNANPLGLRRLVNGEWSDQPVA
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PNILGQNFIAGGRSALGQSLQKSLDATTGEELPYSFHQATDGEIDAAALAAKAAFAEFR
CCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHH
QLSPARRADFLDAIADELDQLGDDFVAIVCQETALPQARIQGERGRTSGQMRLFSKVLRR
HCCHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCCCHHHHCCCCCCCCHHHHHHHHHHHC
GDFVGARIDLALPDRKPLPRVDLRQYRIGVGPVAVFGASNFPLAFSTAGGDTAAALAAGC
CCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCC
PVVFKAHSGHMATADLVASAIIRAAERTQMPKGVFNMIFGNGVGEGLVKHPAIQAVGFTG
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCEEEECCC
SLNGGNALCKMAAERPQPIPVFAEMSSINPVVLLPEALQARGETVAKELAGSVVMGAGQF
CCCCCHHHHHHHHCCCCCCEEEEHHCCCCCEEECCHHHHHHHHHHHHHHHCHHEECCCCC
CTNPGVVIGLRSPAFSKFVEHLTEQMGSQAPQTMLNAGGLRSYNKGVEHLMAHPGVTHLA
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHCC
GKPQEGKQAQAQLFKADVSLLLNGDQLLQEEVFGPTTLLIEVADDAQLKDALQALRGQLT
CCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCEE
ATVIGEPADLSNYSWLQPVLEERVGRILFNGYPTGVEVCEAMVHGGPYPATSDARGTSVG
EEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
TLAIDRFLRPVCYQNLADSQLPPALQNANPLGLRRLVNGEWSDQPVA
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]