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The map label for this gene is cobM [H]

Identifier: 66046251

GI number: 66046251

Start: 3615461

End: 3616210

Strand: Direct

Name: cobM [H]

Synonym: Psyr_3020

Alternate gene names: 66046251

Gene position: 3615461-3616210 (Clockwise)

Preceding gene: 66046250

Following gene: 66046253

Centisome position: 59.33

GC content: 63.33

Gene sequence:

>750_bases
TTGACTGTCTATTTCATCGGCGCAGGCCCTGGCGATCCCGAGCTGATCACCGTCAAGGGCCAACGCCTGATTCGCAGCTG
CCCGGTCATTATCTACGCAGGCTCGCTGGTGCCCCTCGCCGTTCTGGAGGGCCATCAGGCCGTGCAGGTGACCAACAGCG
CCGAGCTGCACCTGGAGCAGATCATCGATCTGATCAAGCGCGCGCACGCACAAGGCCAGGATGTGGCACGCGTGCACTCC
GGGGACCCAAGCCTGTATGGCGCTATCGGCGAGCAGATCCGCCATCTGCGCGAACTGAACATTCCGTTCGAAATCATTCC
GGGGGTCACCGCGACCGCTGCCTGCGCTGCGCTGCTGGGCGTCGAGCTGACCCTGCCGGACGTTTCGCAGAGCGTGATTC
TGACCCGCTATGCCGACAAGACCTCAATGCCCAGCGGCGAGGAACTGGCCAGCCTGGCCAGCCATCGGGCAACCATGGCG
ATTCATCTGGGAGTGAACAACCTGCAGCGGATCGTCGAGGAGCTCATGCCACATTACGGCGCCGATTGCCCGATTGCAGT
GGTGCACCGCGCCAGCTGGCCGGACCAGGACTGGGCCGTTGGCACGCTGGCGGATATTGAGGAAAAGGTACAGGCCAAGG
GCTTTCGCCGTACCGCACTGATTCTGGTCGGACGTGTGCTTGCCGATGACACCTTCAGCGAGTCCTCGCTGTACCGCGCC
GGGCATGCCCACTTGTTCAGGCCGGTGTAG

Upstream 100 bases:

>100_bases
TGATCGAACGGCAGAAAAGCGCGCAGGCCACATTTGCCTTGGCAATCAGCCCTGCGCACAGCGGATAATCTCCCCGCGCT
CATTCACCCCGGAGAATTCA

Downstream 100 bases:

>100_bases
CCAGGCTGCGCTGAGCGCTAGCGCATGGCGTCATGAAAGGCATGCCGACGCTAAGCGCTGGCACGCCTTTCAGCATTGAC
TCCCTCAGGCAGCCGCCTCA

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTVYFIGAGPGDPELITVKGQRLIRSCPVIIYAGSLVPLAVLEGHQAVQVTNSAELHLEQIIDLIKRAHAQGQDVARVHS
GDPSLYGAIGEQIRHLRELNIPFEIIPGVTATAACAALLGVELTLPDVSQSVILTRYADKTSMPSGEELASLASHRATMA
IHLGVNNLQRIVEELMPHYGADCPIAVVHRASWPDQDWAVGTLADIEEKVQAKGFRRTALILVGRVLADDTFSESSLYRA
GHAHLFRPV

Sequences:

>Translated_249_residues
MTVYFIGAGPGDPELITVKGQRLIRSCPVIIYAGSLVPLAVLEGHQAVQVTNSAELHLEQIIDLIKRAHAQGQDVARVHS
GDPSLYGAIGEQIRHLRELNIPFEIIPGVTATAACAALLGVELTLPDVSQSVILTRYADKTSMPSGEELASLASHRATMA
IHLGVNNLQRIVEELMPHYGADCPIAVVHRASWPDQDWAVGTLADIEEKVQAKGFRRTALILVGRVLADDTFSESSLYRA
GHAHLFRPV
>Mature_248_residues
TVYFIGAGPGDPELITVKGQRLIRSCPVIIYAGSLVPLAVLEGHQAVQVTNSAELHLEQIIDLIKRAHAQGQDVARVHSG
DPSLYGAIGEQIRHLRELNIPFEIIPGVTATAACAALLGVELTLPDVSQSVILTRYADKTSMPSGEELASLASHRATMAI
HLGVNNLQRIVEELMPHYGADCPIAVVHRASWPDQDWAVGTLADIEEKVQAKGFRRTALILVGRVLADDTFSESSLYRAG
HAHLFRPV

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=235, Percent_Identity=32.3404255319149, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322922, Length=232, Percent_Identity=26.2931034482759, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26929; Mature: 26798

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGDPELITVKGQRLIRSCPVIIYAGSLVPLAVLEGHQAVQVTNSAELHLEQ
CEEEEEECCCCCCCEEEECCHHHHHHCCEEEEECCCHHHHHHCCCCEEEECCCHHHHHHH
IIDLIKRAHAQGQDVARVHSGDPSLYGAIGEQIRHLRELNIPFEIIPGVTATAACAALLG
HHHHHHHHHCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHC
VELTLPDVSQSVILTRYADKTSMPSGEELASLASHRATMAIHLGVNNLQRIVEELMPHYG
CEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHC
ADCPIAVVHRASWPDQDWAVGTLADIEEKVQAKGFRRTALILVGRVLADDTFSESSLYRA
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHC
GHAHLFRPV
CCCCCCCCC
>Mature Secondary Structure 
TVYFIGAGPGDPELITVKGQRLIRSCPVIIYAGSLVPLAVLEGHQAVQVTNSAELHLEQ
EEEEEECCCCCCCEEEECCHHHHHHCCEEEEECCCHHHHHHCCCCEEEECCCHHHHHHH
IIDLIKRAHAQGQDVARVHSGDPSLYGAIGEQIRHLRELNIPFEIIPGVTATAACAALLG
HHHHHHHHHCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHC
VELTLPDVSQSVILTRYADKTSMPSGEELASLASHRATMAIHLGVNNLQRIVEELMPHYG
CEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHC
ADCPIAVVHRASWPDQDWAVGTLADIEEKVQAKGFRRTALILVGRVLADDTFSESSLYRA
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHC
GHAHLFRPV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]