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The map label for this gene is umuD [H]

Identifier: 66045998

GI number: 66045998

Start: 3349989

End: 3350420

Strand: Reverse

Name: umuD [H]

Synonym: Psyr_2762

Alternate gene names: 66045998

Gene position: 3350420-3349989 (Counterclockwise)

Preceding gene: 66046000

Following gene: 66045997

Centisome position: 54.98

GC content: 55.09

Gene sequence:

>432_bases
ATGAATGTCACTTACCTCGGCACCCTGGCAGAAGAGGGGGCGAAGCTCCCATGGTTCTCATCTTTGGTATCAGCAGGGTT
CCCCTCGCCGGCAGCAGACCACATCGAGAAGCATATATCGCTCGATGAGCTTTTCAGCATTCGGGCGCCGCATGTTTACC
TGGTTACTGTCTTGGGTGAGAGCATGCAGGGGGCAGGCATCCATAGTGGTGATCTTGCGATCGTAGATCGAAGCCTTGAG
GCCGAGCATGGTGATATCGTCGTTGCTGCGCTCAACGCCGAGGCCGTTTGCAAGCGGCTGCACATGCGTAATGACGTCGT
TATCCTTCAGTCAGAAAATCCGCATTTCGCACCTCGACACATCATGGAAGGCGATGAACTGTCCATCTTGGGAGTCGTTC
GTTACAGCGTGCGCGATCATGGCCGGTCATGA

Upstream 100 bases:

>100_bases
CGTCGAAAATGCCCGTCTCTACGATTGACCACGGTAAGGGCAAAGAGTTAACTGTATATGCATACAGTTAATCACTCACC
CACGAAAAACGGCGAACATC

Downstream 100 bases:

>100_bases
GAATGTCTTCGCGCTGATCGACTGCAACTGTTTTTATGCGAGCTGCGAGCGAGCTTTCCGTCCCGACCTGGCAAAGACTC
CCATCGTAGTGCTCAGTAAC

Product: peptidase S24, S26A and S26B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MNVTYLGTLAEEGAKLPWFSSLVSAGFPSPAADHIEKHISLDELFSIRAPHVYLVTVLGESMQGAGIHSGDLAIVDRSLE
AEHGDIVVAALNAEAVCKRLHMRNDVVILQSENPHFAPRHIMEGDELSILGVVRYSVRDHGRS

Sequences:

>Translated_143_residues
MNVTYLGTLAEEGAKLPWFSSLVSAGFPSPAADHIEKHISLDELFSIRAPHVYLVTVLGESMQGAGIHSGDLAIVDRSLE
AEHGDIVVAALNAEAVCKRLHMRNDVVILQSENPHFAPRHIMEGDELSILGVVRYSVRDHGRS
>Mature_143_residues
MNVTYLGTLAEEGAKLPWFSSLVSAGFPSPAADHIEKHISLDELFSIRAPHVYLVTVLGESMQGAGIHSGDLAIVDRSLE
AEHGDIVVAALNAEAVCKRLHMRNDVVILQSENPHFAPRHIMEGDELSILGVVRYSVRDHGRS

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=127, Percent_Identity=41.7322834645669, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1790476, Length=111, Percent_Identity=38.7387387387387, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 15577; Mature: 15577

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTYLGTLAEEGAKLPWFSSLVSAGFPSPAADHIEKHISLDELFSIRAPHVYLVTVLGE
CCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHCCHHHHHHCCCCCEEEEEEECC
SMQGAGIHSGDLAIVDRSLEAEHGDIVVAALNAEAVCKRLHMRNDVVILQSENPHFAPRH
CCCCCCCCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCCCCHH
IMEGDELSILGVVRYSVRDHGRS
CCCCCCEEEEEEEEEHHHCCCCC
>Mature Secondary Structure
MNVTYLGTLAEEGAKLPWFSSLVSAGFPSPAADHIEKHISLDELFSIRAPHVYLVTVLGE
CCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHCCHHHHHHCCCCCEEEEEEECC
SMQGAGIHSGDLAIVDRSLEAEHGDIVVAALNAEAVCKRLHMRNDVVILQSENPHFAPRH
CCCCCCCCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCCCCHH
IMEGDELSILGVVRYSVRDHGRS
CCCCCCEEEEEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]