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The map label for this gene is galE [H]

Identifier: 66045940

GI number: 66045940

Start: 3285422

End: 3286450

Strand: Direct

Name: galE [H]

Synonym: Psyr_2704

Alternate gene names: 66045940

Gene position: 3285422-3286450 (Clockwise)

Preceding gene: 66045934

Following gene: 66045943

Centisome position: 53.92

GC content: 59.09

Gene sequence:

>1029_bases
ATGATTCTGGTTACCGGTGGTGCGGGATACATTGGCGCTCACATCGCGCTCGAGTTGCTTGAAGATGGCCGCGATGTCGT
CGTGCTTGATAACTTGTGCAACAGTTCGCGAGAGCCGTTAAGACGGATAGAGGAACTCTGCGGGCGACAGGTTGCGTTCA
TCCACGGCGACGTGCGCAGCAAAGCGACGTTGCACCGGCTGTTCGCTCAGTACCCTGTCAAGGCAGTGGTGCATTGCGCC
GGACTCAAGGCGGTGGGCGAAAGCGTTCGAGAGCCGCTGCGCTATTTCGAGACCAACGTGAGCGGCAGCGTCAACTTGTG
TCAGGCAATGGCAGAAGCAGGCGTGTTCGACCTGTTATTCAGCTCATCCGCGACGGTTTACGGCGGGTGTGAGCAAATGC
CGCTGGATGAGAACTGCCCACTGGGTTTACCGACCAATCCTTACGGGCACTCCAAACTGATGGCCGAGCATGTGATGCAA
AGCGTCGCCCGCTCGGATCCACGCTGGTCCATCGGTCTGCTGCGCTACTTCAACCCCATTGGTGCGCATCCGTCCGGCCT
GCTGGGCGAGTCACCCTGCAACACGCCGAACAACCTGTTGCCCTTCCTGCTGCAGGTTGCCAATCGACTACGCCCTGCCC
TGCACATATTCGGCAGTGACTACCCCACGCTGGACGGAACAGGTGTGCGTGATTACCTTCATGTGATGGATCTGGCCGAG
GGACACCTGAAGGCGCTGGACAAAATTCATGACGAACGTGGCGTATCCGTCTGGAATCTGGGCACAGGACAGGGTTATTC
GGTGCTTGAGGTGGTGCACGCCTTCGAACGTATCTCCGGCAAAGCTGTGCCGTTGATCTTTGAACCACGCCGGCCCGGAG
ACATTGCAGCATGCTGGTCCGATCCGGGAAAAGCAGCGCGCGAGCTGGATTGGCGGGCCAGGTTCAACCTTGATTCGATG
CTCACCGACGCCTGGCGCTGGCAGTGCATGAACCCTCAGGGTTACAGGCCGACAGCGCTGGTCAGTTGA

Upstream 100 bases:

>100_bases
TCGCAAGCGAGGCTCCTCTGTCGTCCTGTTGAGAAAGGTCACGACGACGAGCCGTCAGCTCGCTTCTTGCCGAGGCGGCG
AAAATCCAGGGAGGACAATC

Downstream 100 bases:

>100_bases
ATTTTATCCAGACGTGTTGCCAGACGTGCTGAACGATCATCACGTTATCGTGACGCCTGCCAGCAAGCGCATGCTAGAAG
TTGGCCGGTGTGTTGGCGCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MILVTGGAGYIGAHIALELLEDGRDVVVLDNLCNSSREPLRRIEELCGRQVAFIHGDVRSKATLHRLFAQYPVKAVVHCA
GLKAVGESVREPLRYFETNVSGSVNLCQAMAEAGVFDLLFSSSATVYGGCEQMPLDENCPLGLPTNPYGHSKLMAEHVMQ
SVARSDPRWSIGLLRYFNPIGAHPSGLLGESPCNTPNNLLPFLLQVANRLRPALHIFGSDYPTLDGTGVRDYLHVMDLAE
GHLKALDKIHDERGVSVWNLGTGQGYSVLEVVHAFERISGKAVPLIFEPRRPGDIAACWSDPGKAARELDWRARFNLDSM
LTDAWRWQCMNPQGYRPTALVS

Sequences:

>Translated_342_residues
MILVTGGAGYIGAHIALELLEDGRDVVVLDNLCNSSREPLRRIEELCGRQVAFIHGDVRSKATLHRLFAQYPVKAVVHCA
GLKAVGESVREPLRYFETNVSGSVNLCQAMAEAGVFDLLFSSSATVYGGCEQMPLDENCPLGLPTNPYGHSKLMAEHVMQ
SVARSDPRWSIGLLRYFNPIGAHPSGLLGESPCNTPNNLLPFLLQVANRLRPALHIFGSDYPTLDGTGVRDYLHVMDLAE
GHLKALDKIHDERGVSVWNLGTGQGYSVLEVVHAFERISGKAVPLIFEPRRPGDIAACWSDPGKAARELDWRARFNLDSM
LTDAWRWQCMNPQGYRPTALVS
>Mature_342_residues
MILVTGGAGYIGAHIALELLEDGRDVVVLDNLCNSSREPLRRIEELCGRQVAFIHGDVRSKATLHRLFAQYPVKAVVHCA
GLKAVGESVREPLRYFETNVSGSVNLCQAMAEAGVFDLLFSSSATVYGGCEQMPLDENCPLGLPTNPYGHSKLMAEHVMQ
SVARSDPRWSIGLLRYFNPIGAHPSGLLGESPCNTPNNLLPFLLQVANRLRPALHIFGSDYPTLDGTGVRDYLHVMDLAE
GHLKALDKIHDERGVSVWNLGTGQGYSVLEVVHAFERISGKAVPLIFEPRRPGDIAACWSDPGKAARELDWRARFNLDSM
LTDAWRWQCMNPQGYRPTALVS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=52.0348837209302, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=52.0348837209302, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=52.0348837209302, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI42516563, Length=332, Percent_Identity=25.9036144578313, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=52.9940119760479, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=26.5193370165746, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI48994969, Length=365, Percent_Identity=25.2054794520548, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=45.7725947521866, Blast_Score=327, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=45.5072463768116, Blast_Score=325, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17539532, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=46.3768115942029, Blast_Score=328, Evalue=5e-91,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=48.5380116959064, Blast_Score=355, Evalue=3e-98,
Organism=Drosophila melanogaster, GI21356223, Length=248, Percent_Identity=24.5967741935484, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37630; Mature: 37630

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGYIGAHIALELLEDGRDVVVLDNLCNSSREPLRRIEELCGRQVAFIHGDVRS
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCHHH
KATLHRLFAQYPVKAVVHCAGLKAVGESVREPLRYFETNVSGSVNLCQAMAEAGVFDLLF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
SSSATVYGGCEQMPLDENCPLGLPTNPYGHSKLMAEHVMQSVARSDPRWSIGLLRYFNPI
CCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCC
GAHPSGLLGESPCNTPNNLLPFLLQVANRLRPALHIFGSDYPTLDGTGVRDYLHVMDLAE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GHLKALDKIHDERGVSVWNLGTGQGYSVLEVVHAFERISGKAVPLIFEPRRPGDIAACWS
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECC
DPGKAARELDWRARFNLDSMLTDAWRWQCMNPQGYRPTALVS
CCCHHHHHCCHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCC
>Mature Secondary Structure
MILVTGGAGYIGAHIALELLEDGRDVVVLDNLCNSSREPLRRIEELCGRQVAFIHGDVRS
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCHHH
KATLHRLFAQYPVKAVVHCAGLKAVGESVREPLRYFETNVSGSVNLCQAMAEAGVFDLLF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
SSSATVYGGCEQMPLDENCPLGLPTNPYGHSKLMAEHVMQSVARSDPRWSIGLLRYFNPI
CCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCC
GAHPSGLLGESPCNTPNNLLPFLLQVANRLRPALHIFGSDYPTLDGTGVRDYLHVMDLAE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GHLKALDKIHDERGVSVWNLGTGQGYSVLEVVHAFERISGKAVPLIFEPRRPGDIAACWS
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECC
DPGKAARELDWRARFNLDSMLTDAWRWQCMNPQGYRPTALVS
CCCHHHHHCCHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]