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The map label for this gene is udg [H]

Identifier: 66045932

GI number: 66045932

Start: 3272446

End: 3273840

Strand: Direct

Name: udg [H]

Synonym: Psyr_2696

Alternate gene names: 66045932

Gene position: 3272446-3273840 (Clockwise)

Preceding gene: 66045931

Following gene: 66045934

Centisome position: 53.7

GC content: 60.57

Gene sequence:

>1395_bases
ATGAAAATCAGCGTTTTCGGTAGCGGATATGTCGGCCTGGTACAAGCGACCGTGCTTGCCGAAGTCGGCCACGATGTGGT
CTGCATGGACATCGATCAGGCCAAAATCGACCAGTTGCGTCAGGGCCAGGTGCATATCTACGAGCCTGGCCTGGCCAATC
TGGTACGTGAAAACCTCGACCAGCAGCGCCTGTGCTTCACCACCGACGAGCAGCTGGCAGTGGAACATGCCGAGGTCCTG
TTCATTGCGGTAGGCACGCCGTCCCGAGCCGATGGCTCCGCCGACCTGAGCGGCTTTTTCGCGGTGGGCGAAGCCATCGC
CCGGCATCGACGCGAACCGCTGATCATCGTCGAGAAGTCCACCGTGCCGGTCGGCAGTGGCGACGCCTTGCGCAGCCACA
TCGACAAGGCGCTGCGTCAGGCGGGCCGGCTGTTGCAGTTCGATATCGTCTCCAATCCGGAGTTTCTCAAGGAGGGCTCG
GCGGTCAACGATTGCCGGCGCCCGGACCGTATTGTCATCGGCTGCGAAAATGAAGCGGTGCGCAACGTCATGCGCGAGCT
GTATGCACCGTTCAACCGCAATCATGAGCGGATCATGTTCATGGACCTGCGCAGCGCCGAACTGACCAAGTACGCCGCCA
ACTGCATGCTGGCAACCAAGATCAGCTTCATCAACCAGATCGCCGAACTGGCCGAGCATCTGGGCGCGGACGTCGAGTCG
GTGCGGTTGGGCATTGGCGCCGACTCACGCATCGGTTACGACTTCATCTACCCCGGTTGCGGTTACGGCGGTTCGTGTTT
TGGCAAAGACATCCGTGCGTTGATTCACAGCGCCCGGGAGGCCCATTGCTCCAACGATCTGCTGTCGGTGGTCGAGGCGA
TCAACGAACGGCAGAAGAACAAACTCTTCGAGCGGGTCAACGCGTTCTATCAGGGCGACCTGCGCGGCAAGACCTTTGCC
CTGTGGGGGCTGGCGTTCAAACCCAACACCGACGACATGCGCGATGCCCCCAGCCGCGTGCTCATGGAAGCGTTGTGGGA
GGCTGGCGCCAGCGTGCGGGCGTTCGACCCCGAGGCCATGCAGGAAACCCAGCGTATTTATGGCCATCGCAAGGACCTGA
TGCTCATGGGCACGCCAGAGTCGGCGCTCAATGAAGCCGATGCATTGATCGTCTGCACCGAATGGCAACAGTTCAAAGCT
CCGGATTTCGAGTTGATCCAGCAGCGGCTGAACGCACCGGTCATCTTCGACGGGCGCAATCTGTACGACACCGAACGACT
GGCAAAACGCGGCTTCCACTACTTCCCCATCGGGCGTGGCGAGTCATGCGATCTGCCAATCCCGCAAAAACAGTGGACGG
CCTGTAACCCGCTTGTCAGCAGCCAGGTTGTGTAA

Upstream 100 bases:

>100_bases
TTCACGGTATCGAAAACTGTGGGTGTCAGCCTGATCGTGGCAGGTGTCTTGACCATCAACCTCCGGCGCCTTCCCCGGCC
ATCACCTCAGGATCTTTCCC

Downstream 100 bases:

>100_bases
CGGCCCTGCTCCGGTGGCCGTCAGTTGCCGACAGTCGCTGGAGCCTGAGTGACGAAATAGTAGATACGCTCGCCGACCTT
GACGCTGTCGACCATTCGCA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKISVFGSGYVGLVQATVLAEVGHDVVCMDIDQAKIDQLRQGQVHIYEPGLANLVRENLDQQRLCFTTDEQLAVEHAEVL
FIAVGTPSRADGSADLSGFFAVGEAIARHRREPLIIVEKSTVPVGSGDALRSHIDKALRQAGRLLQFDIVSNPEFLKEGS
AVNDCRRPDRIVIGCENEAVRNVMRELYAPFNRNHERIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADVES
VRLGIGADSRIGYDFIYPGCGYGGSCFGKDIRALIHSAREAHCSNDLLSVVEAINERQKNKLFERVNAFYQGDLRGKTFA
LWGLAFKPNTDDMRDAPSRVLMEALWEAGASVRAFDPEAMQETQRIYGHRKDLMLMGTPESALNEADALIVCTEWQQFKA
PDFELIQQRLNAPVIFDGRNLYDTERLAKRGFHYFPIGRGESCDLPIPQKQWTACNPLVSSQVV

Sequences:

>Translated_464_residues
MKISVFGSGYVGLVQATVLAEVGHDVVCMDIDQAKIDQLRQGQVHIYEPGLANLVRENLDQQRLCFTTDEQLAVEHAEVL
FIAVGTPSRADGSADLSGFFAVGEAIARHRREPLIIVEKSTVPVGSGDALRSHIDKALRQAGRLLQFDIVSNPEFLKEGS
AVNDCRRPDRIVIGCENEAVRNVMRELYAPFNRNHERIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADVES
VRLGIGADSRIGYDFIYPGCGYGGSCFGKDIRALIHSAREAHCSNDLLSVVEAINERQKNKLFERVNAFYQGDLRGKTFA
LWGLAFKPNTDDMRDAPSRVLMEALWEAGASVRAFDPEAMQETQRIYGHRKDLMLMGTPESALNEADALIVCTEWQQFKA
PDFELIQQRLNAPVIFDGRNLYDTERLAKRGFHYFPIGRGESCDLPIPQKQWTACNPLVSSQVV
>Mature_464_residues
MKISVFGSGYVGLVQATVLAEVGHDVVCMDIDQAKIDQLRQGQVHIYEPGLANLVRENLDQQRLCFTTDEQLAVEHAEVL
FIAVGTPSRADGSADLSGFFAVGEAIARHRREPLIIVEKSTVPVGSGDALRSHIDKALRQAGRLLQFDIVSNPEFLKEGS
AVNDCRRPDRIVIGCENEAVRNVMRELYAPFNRNHERIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADVES
VRLGIGADSRIGYDFIYPGCGYGGSCFGKDIRALIHSAREAHCSNDLLSVVEAINERQKNKLFERVNAFYQGDLRGKTFA
LWGLAFKPNTDDMRDAPSRVLMEALWEAGASVRAFDPEAMQETQRIYGHRKDLMLMGTPESALNEADALIVCTEWQQFKA
PDFELIQQRLNAPVIFDGRNLYDTERLAKRGFHYFPIGRGESCDLPIPQKQWTACNPLVSSQVV

Specific function: Catalyzes The Oxidation Of Udp-Mannac To Udp-N- Acetylmannosaminuronic Acid (Udp-Mannaca). [C]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=470, Percent_Identity=32.9787234042553, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI296040438, Length=372, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI296040443, Length=335, Percent_Identity=33.7313432835821, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI48994968, Length=437, Percent_Identity=26.5446224256293, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788340, Length=365, Percent_Identity=28.2191780821918, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=32.8326180257511, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=35.5932203389831, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51756; Mature: 51756

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVFGSGYVGLVQATVLAEVGHDVVCMDIDQAKIDQLRQGQVHIYEPGLANLVRENLD
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECCCHHHHHHHCCC
QQRLCFTTDEQLAVEHAEVLFIAVGTPSRADGSADLSGFFAVGEAIARHRREPLIIVEKS
CCCEEECCCHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGSGDALRSHIDKALRQAGRLLQFDIVSNPEFLKEGSAVNDCRRPDRIVIGCENEAV
CCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCHHHCCCCCEEEEECCCHHH
RNVMRELYAPFNRNHERIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADVES
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRLGIGADSRIGYDFIYPGCGYGGSCFGKDIRALIHSAREAHCSNDLLSVVEAINERQKN
EEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KLFERVNAFYQGDLRGKTFALWGLAFKPNTDDMRDAPSRVLMEALWEAGASVRAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHH
QETQRIYGHRKDLMLMGTPESALNEADALIVCTEWQQFKAPDFELIQQRLNAPVIFDGRN
HHHHHHHCCCCCEEEEECCHHHHCCCCEEEEEECCHHCCCCCHHHHHHHCCCCEEECCCC
LYDTERLAKRGFHYFPIGRGESCDLPIPQKQWTACNPLVSSQVV
CCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKISVFGSGYVGLVQATVLAEVGHDVVCMDIDQAKIDQLRQGQVHIYEPGLANLVRENLD
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECCCHHHHHHHCCC
QQRLCFTTDEQLAVEHAEVLFIAVGTPSRADGSADLSGFFAVGEAIARHRREPLIIVEKS
CCCEEECCCHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGSGDALRSHIDKALRQAGRLLQFDIVSNPEFLKEGSAVNDCRRPDRIVIGCENEAV
CCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCHHHCCCCCEEEEECCCHHH
RNVMRELYAPFNRNHERIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADVES
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRLGIGADSRIGYDFIYPGCGYGGSCFGKDIRALIHSAREAHCSNDLLSVVEAINERQKN
EEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KLFERVNAFYQGDLRGKTFALWGLAFKPNTDDMRDAPSRVLMEALWEAGASVRAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHH
QETQRIYGHRKDLMLMGTPESALNEADALIVCTEWQQFKAPDFELIQQRLNAPVIFDGRN
HHHHHHHCCCCCEEEEECCHHHHCCCCEEEEEECCHHCCCCCHHHHHHHCCCCEEECCCC
LYDTERLAKRGFHYFPIGRGESCDLPIPQKQWTACNPLVSSQVV
CCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]