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The map label for this gene is appB [H]

Identifier: 66045915

GI number: 66045915

Start: 3251027

End: 3251971

Strand: Direct

Name: appB [H]

Synonym: Psyr_2679

Alternate gene names: 66045915

Gene position: 3251027-3251971 (Clockwise)

Preceding gene: 66045914

Following gene: 66045916

Centisome position: 53.35

GC content: 61.27

Gene sequence:

>945_bases
ATGCTGATGTTCATCCTGCGACGCCTGCTCAGCTCGATACCGACGCTGATTCTGGTTTCGCTGTTCGTCTTCACCCTGCA
GAAGCTGCTGCCGGGTGACCCGGTGCTGGCCATGGCCGGGGAAGAGCGCGATCCGGCGGTCATGGAATACCTGCGCGACA
AATACCGGCTCGATGACCCGATCCCCTTGCAGTACCTGAACTGGGTCGGCAACGTGCTGACCGGCGACCTCGGCACATCG
CTGCGCACCGAACAAGCGGTAACCACGCTGCTGGCGTCGAAACTGCCGGTGACTATCGAACTGGCGGTGCTGGCCCTGCT
GATTGCGCTGTTGATCGGCATTCCCACCGGGATCATTTCGGCGGTGCGCAAAGGCACCGCCGTGGATTACGGGGCCAACG
TGGTGGCGCTGTCGGGGATTTCCATTCCGCACTTCTGGCTGGGCATTCTGCTGATCATGGTGTTTGCGGTGAAACTGCAG
TGGCTGCCTGCCTCCGGCTTTGTGCCGATGGGTGAGGACTTCGGGCAAAACCTGAAGACCCTGATCCTGCCAGCGTTCGT
CTTGGGTGCCGGGCTTTCGGGGATTCTCATGCGCCACACCCGCAGCGCCATGCTGGAAGTACTGCGCACCGACTACGTCC
GCACCGCCCGGGCCAAGGGGTTATTCCCCCGTACAGTCATTCTCAAGCATGCGTTGCGCAACGCGCTGATGCCTATCGTC
ACACTCACGACGCTGCTGTTCGGCGAGTTGCTCGGCGGTGCGGTGCTGACCGAACAGGTATTCAGCATCCCGGGGTTCGG
CAAAATGATCGTCGACGCCGTGTTCAACCGCGACTACGCCGTGGTGCAAGGCGTGGTGTTGTGTGTCGCGATTGGCTTCC
TGATGTTGAACCTGCTGGCCGACGTGCTTTATCGCCTGATCAACCCACGTCTGAGGACTGCCTGA

Upstream 100 bases:

>100_bases
AACAACGTGACCGGTTTTGTCCCTAACCCGGACGGTCTGATTCGTCTGAACAATGTCGCGTTCAAGCCATGACTGACGGG
CGCACCTGCGAGGTTCCGGT

Downstream 100 bases:

>100_bases
TGACCGCTATTGCCAGCCTCCCGCACAGCGCGATCCTGCCCCGCAGTCGCTCGCCTTTTCTGAAGAAATTCCTTGCCAAC
AAAGGCGCGGTACTTGGCGC

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLMFILRRLLSSIPTLILVSLFVFTLQKLLPGDPVLAMAGEERDPAVMEYLRDKYRLDDPIPLQYLNWVGNVLTGDLGTS
LRTEQAVTTLLASKLPVTIELAVLALLIALLIGIPTGIISAVRKGTAVDYGANVVALSGISIPHFWLGILLIMVFAVKLQ
WLPASGFVPMGEDFGQNLKTLILPAFVLGAGLSGILMRHTRSAMLEVLRTDYVRTARAKGLFPRTVILKHALRNALMPIV
TLTTLLFGELLGGAVLTEQVFSIPGFGKMIVDAVFNRDYAVVQGVVLCVAIGFLMLNLLADVLYRLINPRLRTA

Sequences:

>Translated_314_residues
MLMFILRRLLSSIPTLILVSLFVFTLQKLLPGDPVLAMAGEERDPAVMEYLRDKYRLDDPIPLQYLNWVGNVLTGDLGTS
LRTEQAVTTLLASKLPVTIELAVLALLIALLIGIPTGIISAVRKGTAVDYGANVVALSGISIPHFWLGILLIMVFAVKLQ
WLPASGFVPMGEDFGQNLKTLILPAFVLGAGLSGILMRHTRSAMLEVLRTDYVRTARAKGLFPRTVILKHALRNALMPIV
TLTTLLFGELLGGAVLTEQVFSIPGFGKMIVDAVFNRDYAVVQGVVLCVAIGFLMLNLLADVLYRLINPRLRTA
>Mature_314_residues
MLMFILRRLLSSIPTLILVSLFVFTLQKLLPGDPVLAMAGEERDPAVMEYLRDKYRLDDPIPLQYLNWVGNVLTGDLGTS
LRTEQAVTTLLASKLPVTIELAVLALLIALLIGIPTGIISAVRKGTAVDYGANVVALSGISIPHFWLGILLIMVFAVKLQ
WLPASGFVPMGEDFGQNLKTLILPAFVLGAGLSGILMRHTRSAMLEVLRTDYVRTARAKGLFPRTVILKHALRNALMPIV
TLTTLLFGELLGGAVLTEQVFSIPGFGKMIVDAVFNRDYAVVQGVVLCVAIGFLMLNLLADVLYRLINPRLRTA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=41.9871794871795, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=43.75, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=37.2611464968153, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1789888, Length=315, Percent_Identity=35.5555555555556, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787761, Length=314, Percent_Identity=41.0828025477707, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788504, Length=359, Percent_Identity=29.8050139275766, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34261; Mature: 34261

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMFILRRLLSSIPTLILVSLFVFTLQKLLPGDPVLAMAGEERDPAVMEYLRDKYRLDDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
IPLQYLNWVGNVLTGDLGTSLRTEQAVTTLLASKLPVTIELAVLALLIALLIGIPTGIIS
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHH
AVRKGTAVDYGANVVALSGISIPHFWLGILLIMVFAVKLQWLPASGFVPMGEDFGQNLKT
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LILPAFVLGAGLSGILMRHTRSAMLEVLRTDYVRTARAKGLFPRTVILKHALRNALMPIV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TLTTLLFGELLGGAVLTEQVFSIPGFGKMIVDAVFNRDYAVVQGVVLCVAIGFLMLNLLA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DVLYRLINPRLRTA
HHHHHHHCCHHCCC
>Mature Secondary Structure
MLMFILRRLLSSIPTLILVSLFVFTLQKLLPGDPVLAMAGEERDPAVMEYLRDKYRLDDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
IPLQYLNWVGNVLTGDLGTSLRTEQAVTTLLASKLPVTIELAVLALLIALLIGIPTGIIS
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHH
AVRKGTAVDYGANVVALSGISIPHFWLGILLIMVFAVKLQWLPASGFVPMGEDFGQNLKT
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LILPAFVLGAGLSGILMRHTRSAMLEVLRTDYVRTARAKGLFPRTVILKHALRNALMPIV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TLTTLLFGELLGGAVLTEQVFSIPGFGKMIVDAVFNRDYAVVQGVVLCVAIGFLMLNLLA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DVLYRLINPRLRTA
HHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]