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The map label for this gene is dppA [H]

Identifier: 66045914

GI number: 66045914

Start: 3249496

End: 3250998

Strand: Direct

Name: dppA [H]

Synonym: Psyr_2678

Alternate gene names: 66045914

Gene position: 3249496-3250998 (Clockwise)

Preceding gene: 66045913

Following gene: 66045915

Centisome position: 53.33

GC content: 59.02

Gene sequence:

>1503_bases
ATGAAAATCGCACGCGTCGTGACAGGAACATTGTTATTGCTGGCCGCCAACGCTGCCTTCGCCGAATCGACGTTGCGCAT
CGGCATTCAGGACGATCCCGATGTGCTGGATCCGCACCGTTCGCGCACCTACTCCGGCCGCCTGGTCTACACCGCGCTGT
GCGACAAACTGGTGGACGTCAACCCGGACCTGACCTACTCGCCGCAACTGGCCACCGCCTGGAACTGGAGCGAAGACGGT
AAAACCCTGACCATGACGTTGCGCGAAGGCGTGACGTACCACGATGGCGAACCTTTTGATGCCGCCTCGGTGAAGTTCAA
CCTTGATCGCGCCCGCACCCTCCCCGACTCCCTGCGCAAAAGCGAGCTGGCCTCGGTGGACAGCGTCGAGGTGATTGACG
CAAAAACTGTCGCCATCAAGCTCAAGCAAGCCGATGCCACGCTGGTTTCGCAACTGTCGGACCGTGCCGGGATGATGCTC
GCGCCGAAAGCCGCGCAAGGTGAGTTCGCCTCCAACCCGGTCTGCTCCGGCCCTTACAAATTCGTGCAGCGCGTGCAGCA
GGATCGAATCGTACTGGAGCGTTTTGACAACTACTGGAATAAACAGGCTTATCACTTCGACAAAGTGGTGTTCCTGCCGA
TTCCGGACACCTCGGTGCGCCTGGCCAACCTGCGCTCCGGCGATCTGGACATCATCGAGCGCGTGGCGCCAACCGATGTG
AAAACCGTCAAGGGCGACAGCAAGCTGGCGATCTACAACACACCGGGCCTGGGCTACATGCAACTGATGTTCAACATCGG
CAATGGTGAAAAAGCCAACTCGCCGATGGGCAAGGACAAGCGCGTACGCAAGGCGTTTGAGCTGTCCATCGACCGCGATG
CCATTAATCAGGTGGTGTTCGAGGGTCTGTACGCACCAAGCGCTCAGCCGTTCCCGAAAAACAGCCCGTATTACGACAAG
GAACTGCCGATCCCTACTCGCGATATCGAGAAAAGCAAAGCGCTGCTGGCGCAGGCCGGCGTGAAACTGCCGTTGGCGGT
GGACCTGAAAGTGGCCAACAACCCCATCGCGCAACAGGTCGGGCAGATCATTCAGGCCATGGCTGAAGAAGCGGGCTTCA
AGGTCAACCTGATTGCCACGGAATACGCGACGATGCTCAGCGAACAGGCGAGTGGCAACTTCCAGATCGGCATGAGCGCC
TGGTCGGGTCGTCCTGATCCGGATGGCGACATCCATCAGTTCGTGACCTGCAAAGGCGGCCAGAACGACGGCAAGTACTG
CAACGCCAGACTCGACGAACTGCTCAACAAGGCGCGCACCGTGAACGACGTTGCACAACGCCAGGCGCTGTACAACGACG
CGCTGCGCTTGCTGGCCGATGAAGTACCCACCGCCTACCTGTATTTCGACCCGCGAATCATTGCCATGCGTAACAACGTG
ACCGGTTTTGTCCCTAACCCGGACGGTCTGATTCGTCTGAACAATGTCGCGTTCAAGCCATGA

Upstream 100 bases:

>100_bases
CAGGCAGCGCCACGCTGATCCTTCCGACACCCAGCGCTGCCTACACCCAGCGCCTGAATCTGTTCAAGCACCATCAATCC
CTTGCAGTGGAGAGCCAGCC

Downstream 100 bases:

>100_bases
CTGACGGGCGCACCTGCGAGGTTCCGGTATGCTGATGTTCATCCTGCGACGCCTGCTCAGCTCGATACCGACGCTGATTC
TGGTTTCGCTGTTCGTCTTC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKIARVVTGTLLLLAANAAFAESTLRIGIQDDPDVLDPHRSRTYSGRLVYTALCDKLVDVNPDLTYSPQLATAWNWSEDG
KTLTMTLREGVTYHDGEPFDAASVKFNLDRARTLPDSLRKSELASVDSVEVIDAKTVAIKLKQADATLVSQLSDRAGMML
APKAAQGEFASNPVCSGPYKFVQRVQQDRIVLERFDNYWNKQAYHFDKVVFLPIPDTSVRLANLRSGDLDIIERVAPTDV
KTVKGDSKLAIYNTPGLGYMQLMFNIGNGEKANSPMGKDKRVRKAFELSIDRDAINQVVFEGLYAPSAQPFPKNSPYYDK
ELPIPTRDIEKSKALLAQAGVKLPLAVDLKVANNPIAQQVGQIIQAMAEEAGFKVNLIATEYATMLSEQASGNFQIGMSA
WSGRPDPDGDIHQFVTCKGGQNDGKYCNARLDELLNKARTVNDVAQRQALYNDALRLLADEVPTAYLYFDPRIIAMRNNV
TGFVPNPDGLIRLNNVAFKP

Sequences:

>Translated_500_residues
MKIARVVTGTLLLLAANAAFAESTLRIGIQDDPDVLDPHRSRTYSGRLVYTALCDKLVDVNPDLTYSPQLATAWNWSEDG
KTLTMTLREGVTYHDGEPFDAASVKFNLDRARTLPDSLRKSELASVDSVEVIDAKTVAIKLKQADATLVSQLSDRAGMML
APKAAQGEFASNPVCSGPYKFVQRVQQDRIVLERFDNYWNKQAYHFDKVVFLPIPDTSVRLANLRSGDLDIIERVAPTDV
KTVKGDSKLAIYNTPGLGYMQLMFNIGNGEKANSPMGKDKRVRKAFELSIDRDAINQVVFEGLYAPSAQPFPKNSPYYDK
ELPIPTRDIEKSKALLAQAGVKLPLAVDLKVANNPIAQQVGQIIQAMAEEAGFKVNLIATEYATMLSEQASGNFQIGMSA
WSGRPDPDGDIHQFVTCKGGQNDGKYCNARLDELLNKARTVNDVAQRQALYNDALRLLADEVPTAYLYFDPRIIAMRNNV
TGFVPNPDGLIRLNNVAFKP
>Mature_500_residues
MKIARVVTGTLLLLAANAAFAESTLRIGIQDDPDVLDPHRSRTYSGRLVYTALCDKLVDVNPDLTYSPQLATAWNWSEDG
KTLTMTLREGVTYHDGEPFDAASVKFNLDRARTLPDSLRKSELASVDSVEVIDAKTVAIKLKQADATLVSQLSDRAGMML
APKAAQGEFASNPVCSGPYKFVQRVQQDRIVLERFDNYWNKQAYHFDKVVFLPIPDTSVRLANLRSGDLDIIERVAPTDV
KTVKGDSKLAIYNTPGLGYMQLMFNIGNGEKANSPMGKDKRVRKAFELSIDRDAINQVVFEGLYAPSAQPFPKNSPYYDK
ELPIPTRDIEKSKALLAQAGVKLPLAVDLKVANNPIAQQVGQIIQAMAEEAGFKVNLIATEYATMLSEQASGNFQIGMSA
WSGRPDPDGDIHQFVTCKGGQNDGKYCNARLDELLNKARTVNDVAQRQALYNDALRLLADEVPTAYLYFDPRIIAMRNNV
TGFVPNPDGLIRLNNVAFKP

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=529, Percent_Identity=26.6540642722117, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787052, Length=498, Percent_Identity=26.3052208835341, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789887, Length=478, Percent_Identity=27.1966527196653, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081878, Length=504, Percent_Identity=25.7936507936508, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787551, Length=490, Percent_Identity=26.734693877551, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787762, Length=501, Percent_Identity=24.9500998003992, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1787495, Length=479, Percent_Identity=24.8434237995825, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789397, Length=514, Percent_Identity=23.7354085603113, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 55194; Mature: 55194

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIARVVTGTLLLLAANAAFAESTLRIGIQDDPDVLDPHRSRTYSGRLVYTALCDKLVDV
CCCHHHHHHHHHHHHCCCHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCC
NPDLTYSPQLATAWNWSEDGKTLTMTLREGVTYHDGEPFDAASVKFNLDRARTLPDSLRK
CCCCCCCCCCCEEECCCCCCCEEEEEEECCCEECCCCCCCCCEEEEECHHHHCCHHHHHH
SELASVDSVEVIDAKTVAIKLKQADATLVSQLSDRAGMMLAPKAAQGEFASNPVCSGPYK
HHHCCCCCEEEEECEEEEEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHH
FVQRVQQDRIVLERFDNYWNKQAYHFDKVVFLPIPDTSVRLANLRSGDLDIIERVAPTDV
HHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCEEEECCCCCCHHHHHHCCCCCC
KTVKGDSKLAIYNTPGLGYMQLMFNIGNGEKANSPMGKDKRVRKAFELSIDRDAINQVVF
EEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
EGLYAPSAQPFPKNSPYYDKELPIPTRDIEKSKALLAQAGVKLPLAVDLKVANNPIAQQV
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHH
GQIIQAMAEEAGFKVNLIATEYATMLSEQASGNFQIGMSAWSGRPDPDGDIHQFVTCKGG
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
QNDGKYCNARLDELLNKARTVNDVAQRQALYNDALRLLADEVPTAYLYFDPRIIAMRNNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCC
TGFVPNPDGLIRLNNVAFKP
EEECCCCCCEEEECCEECCC
>Mature Secondary Structure
MKIARVVTGTLLLLAANAAFAESTLRIGIQDDPDVLDPHRSRTYSGRLVYTALCDKLVDV
CCCHHHHHHHHHHHHCCCHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCC
NPDLTYSPQLATAWNWSEDGKTLTMTLREGVTYHDGEPFDAASVKFNLDRARTLPDSLRK
CCCCCCCCCCCEEECCCCCCCEEEEEEECCCEECCCCCCCCCEEEEECHHHHCCHHHHHH
SELASVDSVEVIDAKTVAIKLKQADATLVSQLSDRAGMMLAPKAAQGEFASNPVCSGPYK
HHHCCCCCEEEEECEEEEEEEECCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHH
FVQRVQQDRIVLERFDNYWNKQAYHFDKVVFLPIPDTSVRLANLRSGDLDIIERVAPTDV
HHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCEEEECCCCCCHHHHHHCCCCCC
KTVKGDSKLAIYNTPGLGYMQLMFNIGNGEKANSPMGKDKRVRKAFELSIDRDAINQVVF
EEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
EGLYAPSAQPFPKNSPYYDKELPIPTRDIEKSKALLAQAGVKLPLAVDLKVANNPIAQQV
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHH
GQIIQAMAEEAGFKVNLIATEYATMLSEQASGNFQIGMSAWSGRPDPDGDIHQFVTCKGG
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
QNDGKYCNARLDELLNKARTVNDVAQRQALYNDALRLLADEVPTAYLYFDPRIIAMRNNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCC
TGFVPNPDGLIRLNNVAFKP
EEECCCCCCEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]