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The map label for this gene is insK [H]

Identifier: 66045890

GI number: 66045890

Start: 3224856

End: 3225662

Strand: Direct

Name: insK [H]

Synonym: Psyr_2654

Alternate gene names: 66045890

Gene position: 3224856-3225662 (Clockwise)

Preceding gene: 66045889

Following gene: 66045891

Centisome position: 52.92

GC content: 53.9

Gene sequence:

>807_bases
ATGTGCGCCCTTCTGACGCTGGCGGGCCTGGCGCGCAGCACGTTTTACTATCAGGCTCAGGTGCAATCCAGACCCGATCC
AGATGCAGCTCTGAAGCAGGAGATAGAGCGTGTTTATCACGAGGAGAGAGGTCTTTATGGGGCTCGGCGTATCACGGCGG
TCATTCGCAACTCAGGCACGTTGGTCAACAAGAAGGTTGTGGAGCGCTTGATGGCTGAACTGGGCCTCAGATCAGTTGTG
CGACCCAAGAAGTACCGCTCCTATAAGGGCACCGTCGGGAAAATTGCGCCGAATTTGCTGGAGCGCAAGTTCACGGCGCA
ACGCCCGAACCAGAAATGGGTGACCGATGTGACCGAGTTTAAAGTGGCCAATCGAAAGCTGTATCTCTCGCCCGTGATGG
ACCTGTACAACGGTGAGATCGTGGCGTACGAAGTGTCTACCAGGCCGTGCTTCGAGCTGGTCACCAATATGCTGGACAAG
GCTCTCCAGCAGTTGCAGGACGAGCCGAAGCTTGTGATGCACTCGGATCAGGGCTGGCAGTATCAACACGCGCAGTACCG
TCAGAAACTGGCGGTAAAGGGTGTAAAGCAAAGCATGTCTCGTAAGGGAAATTGCCTGGACAATGCCGCAATGGAAAGCT
TCTTTGGTACGCTGAAGTCCGAGTTTTTCTATTTGAAACGATTTGAAAGCATAGAAGAGCTGAAGGCAGGTCTGGATGAG
TACATCCGCTACTACAACCATGACCGCATCAAGCTGAAGCTAAACGGCTTGAGCCCCGTAAAATACAGGGCTCAGGCGGC
GAGCTAA

Upstream 100 bases:

>100_bases
TGGAGAACGCTTACCTAAAAAAGTTGGAAGAGTTGAAGGAGCAGCAACGACGGCAAAAGAAAAAGCCCTGATCGTCAAAC
AACTGAGGAACCGGTTTCCG

Downstream 100 bases:

>100_bases
AACTGTCCAACTTTCGGGGGGCAGTCCACTTTGTGGGACTGCGTGGGCCCCATGGTATATGAAACTTCGCGCGGGAAGCG
TGTAGCACTGCCGGCGATTT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERVYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNHDRIKLKLNGLSPVKYRAQAAS

Sequences:

>Translated_268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERVYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNHDRIKLKLNGLSPVKYRAQAAS
>Mature_268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERVYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNHDRIKLKLNGLSPVKYRAQAAS

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=30.0429184549356, Blast_Score=114, Evalue=7e-26,
Organism=Escherichia coli, GI1789981, Length=263, Percent_Identity=55.1330798479088, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=33.2089552238806, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=33.2089552238806, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=33.2089552238806, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=33.2089552238806, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=33.2089552238806, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30935; Mature: 30935

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERVYHEERGLYGARRITAVIRNSGT
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LVNKKVVERLMAELGLRSVVRPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEF
CHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDKALQQLQDEPKLVMHSDQGWQ
HHHCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
YQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRYYNHDRIKLKLNGLSPVKYRAQAAS
HHHHHCCCEEEEEECCCCCHHHHCCCCC
>Mature Secondary Structure
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERVYHEERGLYGARRITAVIRNSGT
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LVNKKVVERLMAELGLRSVVRPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEF
CHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDKALQQLQDEPKLVMHSDQGWQ
HHHCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
YQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRYYNHDRIKLKLNGLSPVKYRAQAAS
HHHHHCCCEEEEEECCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]