| Definition | Pseudomonas syringae pv. syringae B728a, complete genome. |
|---|---|
| Accession | NC_007005 |
| Length | 6,093,698 |
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The map label for this gene is kduD [H]
Identifier: 66045804
GI number: 66045804
Start: 2981841
End: 2982596
Strand: Reverse
Name: kduD [H]
Synonym: Psyr_2568
Alternate gene names: 66045804
Gene position: 2982596-2981841 (Counterclockwise)
Preceding gene: 66045805
Following gene: 66045803
Centisome position: 48.95
GC content: 64.42
Gene sequence:
>756_bases ATGTCTGAATTCTGGAACAAGGCGTTCGATCTCAATGGCCGTTGTGCGGTCATCACCGGCGGAGCAGCCGGGATTGGCCT TGCCTGTGCCAGCCTGCTGGTCGCGCGCGGCGCGCGGGTCGCACTGCTGGACCGTGACCCGGCAGTGGCCGAGGTTGCCG CCGGCCTGGGCAGCGGGCACCTCGGTATCGCGGTCGACCTGCGCCGGGTCGATCAGGTCAACAGCACCATCGACAGCGTC TTCGAGCATTTCCAGCGCATCGATTATCTGGTCAACAGTGCCGGGGTAGCCATGCTGGACAAGGCTGTCGACGTCAGCGA AGAGGCCTGGGACACGACGCTGGACATCAACCTCAAGGCCAGTTTCTTCGTCGCCCAGGCCTGCGCGCGACACATGCTCG GTCAAGGCAGCGGACGCATCGTCAATCTTGCCTCTCAGGCGGCGGTCATTGGCCTGGACCGGCACGTCGCCTACTGCGCG AGCAAGGCCGCAGTGGTCGGCATGACCAAAGTGCTGGCCATGGAGTGGGCACCACACATCAACGTCAACGCCATCTCGCC CACCATCGTCGAGACCGCGCTGGGCAAAAAAGCCTGGGCGGGCGAAGTCGGAGAACGGGCCAAAACGCAGATCCCGGCAG GCCGCTTCGCCCAGCCGGAGGAAATAGCCGGGCTGGCCCTGTACCTGCTCAGCGACGCCGCCAGCATGATCACCGGCGAA AACGTAGTGATCGACGGCGGCTACAGCATCCAGTAA
Upstream 100 bases:
>100_bases CGGCCTCTTCGCGAACAAGTTCGCTCCCACGGCCTTCGGCCAGAATCAAAAGCTAACGTGTTTGAATCTTCAAAAAAACA GCGCTACAGGAGTCATCTTC
Downstream 100 bases:
>100_bases TTCATTTTTCTGTCGTGAGGTTCATCGTCATGTCCACCGTCACCGAACGCACTGCCGAACAACTTTCACCGGTCATCCCG AAAACCATGCAGGCCGTGGT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MSEFWNKAFDLNGRCAVITGGAAGIGLACASLLVARGARVALLDRDPAVAEVAAGLGSGHLGIAVDLRRVDQVNSTIDSV FEHFQRIDYLVNSAGVAMLDKAVDVSEEAWDTTLDINLKASFFVAQACARHMLGQGSGRIVNLASQAAVIGLDRHVAYCA SKAAVVGMTKVLAMEWAPHINVNAISPTIVETALGKKAWAGEVGERAKTQIPAGRFAQPEEIAGLALYLLSDAASMITGE NVVIDGGYSIQ
Sequences:
>Translated_251_residues MSEFWNKAFDLNGRCAVITGGAAGIGLACASLLVARGARVALLDRDPAVAEVAAGLGSGHLGIAVDLRRVDQVNSTIDSV FEHFQRIDYLVNSAGVAMLDKAVDVSEEAWDTTLDINLKASFFVAQACARHMLGQGSGRIVNLASQAAVIGLDRHVAYCA SKAAVVGMTKVLAMEWAPHINVNAISPTIVETALGKKAWAGEVGERAKTQIPAGRFAQPEEIAGLALYLLSDAASMITGE NVVIDGGYSIQ >Mature_250_residues SEFWNKAFDLNGRCAVITGGAAGIGLACASLLVARGARVALLDRDPAVAEVAAGLGSGHLGIAVDLRRVDQVNSTIDSVF EHFQRIDYLVNSAGVAMLDKAVDVSEEAWDTTLDINLKASFFVAQACARHMLGQGSGRIVNLASQAAVIGLDRHVAYCAS KAAVVGMTKVLAMEWAPHINVNAISPTIVETALGKKAWAGEVGERAKTQIPAGRFAQPEEIAGLALYLLSDAASMITGEN VVIDGGYSIQ
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=36.6255144032922, Blast_Score=144, Evalue=8e-35, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=32.8063241106719, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=35.2941176470588, Blast_Score=124, Evalue=9e-29, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=34.6938775510204, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI66933014, Length=181, Percent_Identity=35.3591160220994, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.3846153846154, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=31.4285714285714, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.8548387096774, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=31.3253012048193, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=32.8125, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=34.010152284264, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI59889578, Length=222, Percent_Identity=29.7297297297297, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=32.156862745098, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI224922801, Length=188, Percent_Identity=34.0425531914894, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=29.5336787564767, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=28.9156626506024, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=32.4175824175824, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=27.9166666666667, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=32.4175824175824, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=5e-12, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=36.144578313253, Blast_Score=154, Evalue=6e-39, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=38.4920634920635, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=30.7053941908714, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=31.0077519379845, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.8897637795276, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=30.4878048780488, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=30.7392996108949, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.8367346938775, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.5140562248996, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=28.8065843621399, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=28.0334728033473, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787891, Length=239, Percent_Identity=25.5230125523013, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=29.3172690763052, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=33.4677419354839, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=33.4677419354839, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=31.7269076305221, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=32.2709163346614, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.8548387096774, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.8007662835249, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.1204819277108, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.7709923664122, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=30.952380952381, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=31.8352059925094, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=31.5217391304348, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=30.3846153846154, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=30.5343511450382, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.5454545454545, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=30.3703703703704, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=29.7297297297297, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=32.8, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.277566539924, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=29.7794117647059, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=29.1187739463602, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=30.6201550387597, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.5471698113208, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=28.1368821292776, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=28.6821705426357, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=29.7979797979798, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17568967, Length=240, Percent_Identity=25.8333333333333, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=29.6875, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.4725274725275, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=1e-22, Organism=Saccharomyces cerevisiae, GI6322861, Length=243, Percent_Identity=29.2181069958848, Blast_Score=86, Evalue=5e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=33.4677419354839, Blast_Score=125, Evalue=3e-29, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=31.1740890688259, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=32.9218106995885, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=29.6747967479675, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=33.6683417085427, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI17737361, Length=247, Percent_Identity=32.3886639676113, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI281364892, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=31.0526315789474, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21358495, Length=242, Percent_Identity=25.2066115702479, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI221510726, Length=173, Percent_Identity=29.4797687861272, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26278; Mature: 26147
Theoretical pI: Translated: 5.29; Mature: 5.29
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEFWNKAFDLNGRCAVITGGAAGIGLACASLLVARGARVALLDRDPAVAEVAAGLGSGH CCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCC LGIAVDLRRVDQVNSTIDSVFEHFQRIDYLVNSAGVAMLDKAVDVSEEAWDTTLDINLKA EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCEEEEEECH SFFVAQACARHMLGQGSGRIVNLASQAAVIGLDRHVAYCASKAAVVGMTKVLAMEWAPHI HHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC NVNAISPTIVETALGKKAWAGEVGERAKTQIPAGRFAQPEEIAGLALYLLSDAASMITGE CCCCCCHHHHHHHHCCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC NVVIDGGYSIQ EEEEECCCCCC >Mature Secondary Structure SEFWNKAFDLNGRCAVITGGAAGIGLACASLLVARGARVALLDRDPAVAEVAAGLGSGH CCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCC LGIAVDLRRVDQVNSTIDSVFEHFQRIDYLVNSAGVAMLDKAVDVSEEAWDTTLDINLKA EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCEEEEEECH SFFVAQACARHMLGQGSGRIVNLASQAAVIGLDRHVAYCASKAAVVGMTKVLAMEWAPHI HHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC NVNAISPTIVETALGKKAWAGEVGERAKTQIPAGRFAQPEEIAGLALYLLSDAASMITGE CCCCCCHHHHHHHHCCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC NVVIDGGYSIQ EEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]