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The map label for this gene is dppB [H]

Identifier: 66045774

GI number: 66045774

Start: 2953453

End: 2954427

Strand: Direct

Name: dppB [H]

Synonym: Psyr_2538

Alternate gene names: 66045774

Gene position: 2953453-2954427 (Clockwise)

Preceding gene: 66045773

Following gene: 66045775

Centisome position: 48.47

GC content: 60.72

Gene sequence:

>975_bases
ATGATTGGCTGGGCGCTGCGTCGGTTGACTCAGTCGTTGCTGGTCATCCTGTTGATGACGCTGGTGGTGTTCGTCGGCCT
CAATGCCATCGGCAACCCGATGGACATTCTGGTCGGTGAAGACCTCAATCAGGCCGAGCGTCTGCAGGCCATTGCGCATT
TGGGCCTTGACCAGCCGCTGTGGCAGCAGTACCTGATTTTTCTCAAGGGCGCGATTCACGGCAATCTGGGGCAAAGCTTC
GTGTATCACGAGGATGCCATGCGCCTGATTCTGCAGCGTTTGCCCGCAACCTTCGAACTGGCGTTCAGTGCCCTGTTTCT
GGCGGTGGTCATCGGTGTGCCGCTGGGCATGTTTGCCGGTATGTACCCCGAGCATCCGCTGTCCCGGTTGATGATGGCCG
CCAGCATTGTCGGCTTCTCGCTGCCAGCCTTCTGGGTGGCCTTGATGATGATCATGCTGTTCTCCATCACCCTCGGCTGG
CTGCCGGCCAGCGGCCGCGGCGAAACCCGTGAGTGGCTGGGCGTGCAATGGTCATGGCTGACGCTGGACGGTTTGCAGCA
CCTGCTATTGCCGGCGCTGAACCTGGCGCTGTTCAAGATTTCGCTGGTGCTGCGCCTGACCCGTGCGGGCGTGCGCGAAG
TGCTGCCCCAGGAATTCGTCAAGTTCGCCCGGGCCAAGGGCCTGTCACCGATGCGCGTGATGTGCATGCACGTCATGCGC
AACACCATGATTCCGGTGGTGACGGTGCTGGCCATGGAACTGGGCTCGACCATCGCCTATGCCGTGGTGACTGAAAGCAT
CTTTGCCTGGCCGGGTGCCGGCAAGCTGATTCTCGACAGCATCAACATGCTCGACCGCCCGGTGGTGGTCGCTTACCTGA
TGGTGGTCGTGGTGATTTTCGTGGTGCTCAACCTGATCGTCGACGGCTTGTATTACCTGCTGGACCCACGCGTACGCATC
GAGGCATCGCGATGA

Upstream 100 bases:

>100_bases
ACATCGCCCTGCATTTCGACACCATGCTCGATTACGCCGAGCCAGAGCTGCTGGGCGATGAGTGGGTCGTCAGCCAGCCA
GACGCCGCAGAGTTGCGCCA

Downstream 100 bases:

>100_bases
ATGTCATTGAAAAAGCCCCGATCGGCAGGACGCTGCTGCAGGCCCAATCGCCCTGGCGACGAGTGCTGACCGAGTTCTTC
AGCTCGCCCACGGCGGTGAC

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIGWALRRLTQSLLVILLMTLVVFVGLNAIGNPMDILVGEDLNQAERLQAIAHLGLDQPLWQQYLIFLKGAIHGNLGQSF
VYHEDAMRLILQRLPATFELAFSALFLAVVIGVPLGMFAGMYPEHPLSRLMMAASIVGFSLPAFWVALMMIMLFSITLGW
LPASGRGETREWLGVQWSWLTLDGLQHLLLPALNLALFKISLVLRLTRAGVREVLPQEFVKFARAKGLSPMRVMCMHVMR
NTMIPVVTVLAMELGSTIAYAVVTESIFAWPGAGKLILDSINMLDRPVVVAYLMVVVVIFVVLNLIVDGLYYLLDPRVRI
EASR

Sequences:

>Translated_324_residues
MIGWALRRLTQSLLVILLMTLVVFVGLNAIGNPMDILVGEDLNQAERLQAIAHLGLDQPLWQQYLIFLKGAIHGNLGQSF
VYHEDAMRLILQRLPATFELAFSALFLAVVIGVPLGMFAGMYPEHPLSRLMMAASIVGFSLPAFWVALMMIMLFSITLGW
LPASGRGETREWLGVQWSWLTLDGLQHLLLPALNLALFKISLVLRLTRAGVREVLPQEFVKFARAKGLSPMRVMCMHVMR
NTMIPVVTVLAMELGSTIAYAVVTESIFAWPGAGKLILDSINMLDRPVVVAYLMVVVVIFVVLNLIVDGLYYLLDPRVRI
EASR
>Mature_324_residues
MIGWALRRLTQSLLVILLMTLVVFVGLNAIGNPMDILVGEDLNQAERLQAIAHLGLDQPLWQQYLIFLKGAIHGNLGQSF
VYHEDAMRLILQRLPATFELAFSALFLAVVIGVPLGMFAGMYPEHPLSRLMMAASIVGFSLPAFWVALMMIMLFSITLGW
LPASGRGETREWLGVQWSWLTLDGLQHLLLPALNLALFKISLVLRLTRAGVREVLPQEFVKFARAKGLSPMRVMCMHVMR
NTMIPVVTVLAMELGSTIAYAVVTESIFAWPGAGKLILDSINMLDRPVVVAYLMVVVVIFVVLNLIVDGLYYLLDPRVRI
EASR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=35.0148367952522, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=35.2941176470588, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1787053, Length=322, Percent_Identity=31.3664596273292, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=31.25, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787761, Length=328, Percent_Identity=35.6707317073171, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=30.4347826086957, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788504, Length=281, Percent_Identity=25.9786476868327, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36082; Mature: 36082

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGWALRRLTQSLLVILLMTLVVFVGLNAIGNPMDILVGEDLNQAERLQAIAHLGLDQPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHHHHCCCCCHH
WQQYLIFLKGAIHGNLGQSFVYHEDAMRLILQRLPATFELAFSALFLAVVIGVPLGMFAG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
MYPEHPLSRLMMAASIVGFSLPAFWVALMMIMLFSITLGWLPASGRGETREWLGVQWSWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEH
TLDGLQHLLLPALNLALFKISLVLRLTRAGVREVLPQEFVKFARAKGLSPMRVMCMHVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTMIPVVTVLAMELGSTIAYAVVTESIFAWPGAGKLILDSINMLDRPVVVAYLMVVVVIF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLNLIVDGLYYLLDPRVRIEASR
HHHHHHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MIGWALRRLTQSLLVILLMTLVVFVGLNAIGNPMDILVGEDLNQAERLQAIAHLGLDQPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHHHHCCCCCHH
WQQYLIFLKGAIHGNLGQSFVYHEDAMRLILQRLPATFELAFSALFLAVVIGVPLGMFAG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
MYPEHPLSRLMMAASIVGFSLPAFWVALMMIMLFSITLGWLPASGRGETREWLGVQWSWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEH
TLDGLQHLLLPALNLALFKISLVLRLTRAGVREVLPQEFVKFARAKGLSPMRVMCMHVMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTMIPVVTVLAMELGSTIAYAVVTESIFAWPGAGKLILDSINMLDRPVVVAYLMVVVVIF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLNLIVDGLYYLLDPRVRIEASR
HHHHHHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]