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The map label for this gene is hsaB [H]

Identifier: 66045642

GI number: 66045642

Start: 2787445

End: 2787930

Strand: Reverse

Name: hsaB [H]

Synonym: Psyr_2406

Alternate gene names: 66045642

Gene position: 2787930-2787445 (Counterclockwise)

Preceding gene: 66045643

Following gene: 66045641

Centisome position: 45.75

GC content: 58.85

Gene sequence:

>486_bases
ATGATAGAACCCGGTATTTACAAAGAAGTCATGGCGTCATTCCCTTCGGGCGTGACCATCGTCACCACCCTGGACCCTGA
GGGCAATCTGGTCGGCATTACTGCCAGCGCATTCAGCGCGCTGTCCATCGACCCGGCACTGGTGCTGTTCTGCCCCAACT
ACGAATCGGACACTTACCCGGTGTTGCGCGACAGCAGGAAATTCGCGATTCACCTGCTGTCTGCCGATCAGCAGACAGAA
GCCTATGCGTTTGCCAGCAAGGGCAAGGACAAGACCAAGGGCATCGAGTGGCAGTTGAGCGAGCTGGGTAACCCGCTGCT
GGGCAACTCCACAGCGATCATCGAGTGTGAACTGTGGCGCGAATACGACGGCGGCGATCACGCGATCATTGTCGGCGCGG
TAAAAAATCTGATCCTGCCCGCGACGCCGGTCACACCGATGGTCTATCACCGGGGCAAGATGGGCGCACTGCCGGCCATC
GTCTGA

Upstream 100 bases:

>100_bases
GACTCCGTGCTGGCCTACACCGAACTGAAAACGGTGTGGATCAACCTTTCGCAGGCGCCCATGCCTGATCCATTTGTCAT
GCGTTAACGAGGCCGCTGCG

Downstream 100 bases:

>100_bases
GGCGGCGCAGGGCGGTTTTGGTGGTTGCAGGCACGGGCGTGATAAACTCGGCCGCGACCCGGGTTCATCCGTCCGGGCCA
TGCAGCAGCCCGCGCAGTGT

Product: flavin reductase-like

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MIEPGIYKEVMASFPSGVTIVTTLDPEGNLVGITASAFSALSIDPALVLFCPNYESDTYPVLRDSRKFAIHLLSADQQTE
AYAFASKGKDKTKGIEWQLSELGNPLLGNSTAIIECELWREYDGGDHAIIVGAVKNLILPATPVTPMVYHRGKMGALPAI
V

Sequences:

>Translated_161_residues
MIEPGIYKEVMASFPSGVTIVTTLDPEGNLVGITASAFSALSIDPALVLFCPNYESDTYPVLRDSRKFAIHLLSADQQTE
AYAFASKGKDKTKGIEWQLSELGNPLLGNSTAIIECELWREYDGGDHAIIVGAVKNLILPATPVTPMVYHRGKMGALPAI
V
>Mature_161_residues
MIEPGIYKEVMASFPSGVTIVTTLDPEGNLVGITASAFSALSIDPALVLFCPNYESDTYPVLRDSRKFAIHLLSADQQTE
AYAFASKGKDKTKGIEWQLSELGNPLLGNSTAIIECELWREYDGGDHAIIVGAVKNLILPATPVTPMVYHRGKMGALPAI
V

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=145, Percent_Identity=24.8275862068966, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 17353; Mature: 17353

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEPGIYKEVMASFPSGVTIVTTLDPEGNLVGITASAFSALSIDPALVLFCPNYESDTYP
CCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEHHCCEEEECCCEEEEECCCCCCCCCC
VLRDSRKFAIHLLSADQQTEAYAFASKGKDKTKGIEWQLSELGNPLLGNSTAIIECELWR
EEECCCEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEHHHCCCCCCCCCEEEEEEEEEE
EYDGGDHAIIVGAVKNLILPATPVTPMVYHRGKMGALPAIV
CCCCCCCEEEEEEHHHHCCCCCCCCHHEEECCCCCCCCCCC
>Mature Secondary Structure
MIEPGIYKEVMASFPSGVTIVTTLDPEGNLVGITASAFSALSIDPALVLFCPNYESDTYP
CCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEHHCCEEEECCCEEEEECCCCCCCCCC
VLRDSRKFAIHLLSADQQTEAYAFASKGKDKTKGIEWQLSELGNPLLGNSTAIIECELWR
EEECCCEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEHHHCCCCCCCCCEEEEEEEEEE
EYDGGDHAIIVGAVKNLILPATPVTPMVYHRGKMGALPAIV
CCCCCCCEEEEEEHHHHCCCCCCCCHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]