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The map label for this gene is arlS [H]

Identifier: 66045610

GI number: 66045610

Start: 2752948

End: 2754252

Strand: Reverse

Name: arlS [H]

Synonym: Psyr_2374

Alternate gene names: 66045610

Gene position: 2754252-2752948 (Counterclockwise)

Preceding gene: 66045611

Following gene: 66045605

Centisome position: 45.2

GC content: 61.07

Gene sequence:

>1305_bases
ATGATTGACTTCGCTCGCCGACGTGGCAGCCTGCATCGCCTCGTCAGCGTGATAATTCTCGGTTTCGGGCTGCTGATGAC
CACCGGCCTGACCACCCTCGCGTTCATGAGCCAGGACCTTGTTGATCATCCGATCTGGAAGGATCTGCTTGAGACCGCGA
CCGCCAACACGCTTGCAGACGACGTGCTGCCCGCGGCGCAGAAAGACGCCAGGATCCAGGTCTGGAAACTGTCAGGCAGC
ACGCCGGCAGCCGGCATGCCGCCCTCTCTCGCTGCACTCGCACCTGGCTATTACAGTGAGGGCGATCTGGACCGCCAGGA
CGCTGACAATGGCGATCGCGACTATGCGGTGCTGGTGACCTCGCTTGGCAGAGAGCGCCTGATCGCCGCCATCGACATCA
GCGATCTGGAGCGGGAGCAGAACTTCATCGCGCTGGTGGGGGCGATGTTTCTGGTACTCAATCTGATTCTGATCATTGCT
GTGATCGCCTGGTTGTACGTGCGCCTGCATCTTCCGGTTCAGGGGCTGGCACTGGGCATGAAGCAACTCGACCCGGAGCG
CCCCGCCCAGCGATTGCCAGTGCACTACGCTCAGGAAGAGCTCAAGGACATTGCCTGCGGAATCAACGCGCACCTGGAAC
GGGTCGAACAATTCATGGCCCGCGAACGCGCGCTGCTGGATCAGGCCAGCCACGAATTCCGCACGCCTATCGCCGTGATC
AGCGGTGCGCTGGATATCCTCGCCAGGCAAAAACTGCCGCCGCGTGCAGCGCCGCCACTGCAACGCATGCGAGCCACCGT
GGAAAACCTGACGGAAATCATGGTTGCGCTGCTTTACCTGTCGCGTGAGCCGTTGACCTCCAACCGGGATGACCCGATCG
AGCTTGATCGTCTGCTGCCCGGCCTGGTCAAGGATCATGAGCATTTGCTCGACGGCAAGCCGGTGAAGTTCTCGGTGCAG
ATCCACCAGACCCTGACTCTGCACGTGCCGGAAGCAATGCTACGCATTGCCGTCGGCAATCTGTTGCGCAATGCGGCAGA
TAACACCTACGACGGCACCATCGCTGTGCGACTCAAGGATGATGTGTTGAGCGTGACCGATTCGGGTGAAGGGTTCGACA
CCGAGCAGGCTTCCCGGCATTACCTGTCGCTGCTGAGGAACCCGATCAGGACGGGCAGTGGCAAAGGCCTCGGGCTGTTT
CTGGTGCGACGTATCTGTGAACGCTTTCAGTGGACACTGACGCTGGAGTCAATGCCGACGCTGGGCACCCGGGCAGGACT
CGACTTCCGCAGTCGGCCGGTTTGA

Upstream 100 bases:

>100_bases
ATGCACCTGCTCAGAAAAACCATTGATGGCGAGCGTGCTGCCGGGCAAAAATTGCTGCATACCGTGCAGGGCATCGGTTT
TCGTCTGTGCGTGTGCGCAC

Downstream 100 bases:

>100_bases
CCCGCAATAAAAAGCCCCTGCCATACATAGACAAGGGCTCTTTAACTGCGCTGGCCGGTCAGCGGCGCTTCATGCGGTCG
ATGATCACCGCCAGCAACAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLADDVLPAAQKDARIQVWKLSGS
TPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVTSLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIA
VIAWLYVRLHLPVQGLALGMKQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLPGLVKDHEHLLDGKPVKFSVQ
IHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKDDVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLF
LVRRICERFQWTLTLESMPTLGTRAGLDFRSRPV

Sequences:

>Translated_434_residues
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLADDVLPAAQKDARIQVWKLSGS
TPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVTSLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIA
VIAWLYVRLHLPVQGLALGMKQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLPGLVKDHEHLLDGKPVKFSVQ
IHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKDDVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLF
LVRRICERFQWTLTLESMPTLGTRAGLDFRSRPV
>Mature_434_residues
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLADDVLPAAQKDARIQVWKLSGS
TPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVTSLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIA
VIAWLYVRLHLPVQGLALGMKQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLPGLVKDHEHLLDGKPVKFSVQ
IHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKDDVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLF
LVRRICERFQWTLTLESMPTLGTRAGLDFRSRPV

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=28.3185840707965, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=324, Percent_Identity=27.4691358024691, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790551, Length=244, Percent_Identity=26.6393442622951, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48153; Mature: 48153

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLAD
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DVLPAAQKDARIQVWKLSGSTPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVT
HHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
SLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIAVIAWLYVRLHLPVQGLALGM
HCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
HHCCCCCHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GLVKDHEHLLDGKPVKFSVQIHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKD
HHHHHHHHHHCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLFLVRRICERFQWTLTLESMPT
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEECCCCC
LGTRAGLDFRSRPV
CCCCCCCCCCCCCC
>Mature Secondary Structure
MIDFARRRGSLHRLVSVIILGFGLLMTTGLTTLAFMSQDLVDHPIWKDLLETATANTLAD
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DVLPAAQKDARIQVWKLSGSTPAAGMPPSLAALAPGYYSEGDLDRQDADNGDRDYAVLVT
HHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
SLGRERLIAAIDISDLEREQNFIALVGAMFLVLNLILIIAVIAWLYVRLHLPVQGLALGM
HCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KQLDPERPAQRLPVHYAQEELKDIACGINAHLERVEQFMARERALLDQASHEFRTPIAVI
HHCCCCCHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SGALDILARQKLPPRAAPPLQRMRATVENLTEIMVALLYLSREPLTSNRDDPIELDRLLP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GLVKDHEHLLDGKPVKFSVQIHQTLTLHVPEAMLRIAVGNLLRNAADNTYDGTIAVRLKD
HHHHHHHHHHCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DVLSVTDSGEGFDTEQASRHYLSLLRNPIRTGSGKGLGLFLVRRICERFQWTLTLESMPT
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEECCCCC
LGTRAGLDFRSRPV
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA