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The map label for this gene is argD2 [H]

Identifier: 66045594

GI number: 66045594

Start: 2734832

End: 2736034

Strand: Direct

Name: argD2 [H]

Synonym: Psyr_2358

Alternate gene names: 66045594

Gene position: 2734832-2736034 (Clockwise)

Preceding gene: 66045592

Following gene: 66045595

Centisome position: 44.88

GC content: 62.68

Gene sequence:

>1203_bases
ATGACCGCCACCTGCCTGATGAGCACTTACCAACCTCTGGCCCTGAGCTTCACACATGGTCTGGGCACACGTCTGTGGGA
CCATAGCGGACGCGAGTACCTGGACGCCGTGGCGGGCGTAGCCGTGACCAACGTGGGGCACTCGCATCCACTGCTGGTCG
AGGCGATTCGCGATCAGGCGGGCCTGCTGTTGCACACCTCCAACCTGTACACCATCGACTGGCAGAAACGCCTGGCGCAG
AAACTGACGGCCTTGTCAGGGCTGGACGCGGTGTTTTTCAACAACTCCGGTGCCGAGGCCAACGAGACTGCGCTCAAGCT
GGCGCGCCTGCATGGCTGGCACAAGTACATCGAACGGCCTTTGGTCGTGGTCATGGAAAACGCCTTCCACGGCCGCACCC
TGGGCACATTGTCGGCCAGTGACGGGCCGGCCGTACGCCTGGGTTTCAGTACCTTGCCGGGCGATTACATCAAAGTGCCC
TTTGGCGATCTGGCAGCGTTCGACAAGGTTTGTACGACGTATGGGCATCGGATCTGCGCCGTGCTGGTCGAACCGATTCA
GGGCGAGGGCGGCGCGCAGGTGGCACCCGCCGGGTATCTCAAGGCCTTGAGGGAGCGTTGCACACGGCGTGACTGGCTGT
TGATGCTCGACGAAATCCAGACCGGTATGGGCCGGACAGGCAAGTGGTTTGCCTTTCAGCATGAGGGCATCGTTCCCGAC
GTCATGACCCTGGCCAAGGGGTTGGGCAACGGTATACCGATTGGTGCTTGCCTGGCACGGGGCAGGGCGGCGCAACTGTT
CACGCCCGGCAGCCACGGCAGCACCTTCGGCGGTAATCCGCTGGCCTGTCGGGTCGGCTGCACGGTGATCGACATCATCG
AACGGCAGGTGCTGGTGGAAAACGCCGCACTGCAAGGCCGGCAGTTGCTGGAAGGGCTGCGCACTGCGCTGGGTGCCCAC
CCGAACGTGCTGGAAGTTCGTGGCCAGGGTTTGATGATAGGGATCGAGTTACGCCAGGCGATACCCGAACTGACACGCAT
CGCAGCCGAGCAACATGGCCTGTTGATCAATGTCACCCGGGGCAAAATCATCCGCCTGTTACCGCCCTTGGTGCTGGACG
CCGCTGAAGTGGGGCAGATTGTCCAAGGCCTGACGGCGAGCCTCGACAGCGCCTGTGATCGGTCGTTTGCACGCTCTGCC
TGA

Upstream 100 bases:

>100_bases
CAATCCTGGCTTTAAAATGATTGAAGTATTTCGCTGTTTATCCATTTGAGGTGGTTAACGATACTGCAAAAACCGAAACA
TACCCAAGGAACTTCACCTC

Downstream 100 bases:

>100_bases
CGCAACGGATTAAGGAAAAGGACTACATCGGGCTGTACCGGGATGACCCATATGCGGTAGAACAGATCAGCATCGTGTCG
GTCTGTACGCGATGGCTACC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT 2 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTATCLMSTYQPLALSFTHGLGTRLWDHSGREYLDAVAGVAVTNVGHSHPLLVEAIRDQAGLLLHTSNLYTIDWQKRLAQ
KLTALSGLDAVFFNNSGAEANETALKLARLHGWHKYIERPLVVVMENAFHGRTLGTLSASDGPAVRLGFSTLPGDYIKVP
FGDLAAFDKVCTTYGHRICAVLVEPIQGEGGAQVAPAGYLKALRERCTRRDWLLMLDEIQTGMGRTGKWFAFQHEGIVPD
VMTLAKGLGNGIPIGACLARGRAAQLFTPGSHGSTFGGNPLACRVGCTVIDIIERQVLVENAALQGRQLLEGLRTALGAH
PNVLEVRGQGLMIGIELRQAIPELTRIAAEQHGLLINVTRGKIIRLLPPLVLDAAEVGQIVQGLTASLDSACDRSFARSA

Sequences:

>Translated_400_residues
MTATCLMSTYQPLALSFTHGLGTRLWDHSGREYLDAVAGVAVTNVGHSHPLLVEAIRDQAGLLLHTSNLYTIDWQKRLAQ
KLTALSGLDAVFFNNSGAEANETALKLARLHGWHKYIERPLVVVMENAFHGRTLGTLSASDGPAVRLGFSTLPGDYIKVP
FGDLAAFDKVCTTYGHRICAVLVEPIQGEGGAQVAPAGYLKALRERCTRRDWLLMLDEIQTGMGRTGKWFAFQHEGIVPD
VMTLAKGLGNGIPIGACLARGRAAQLFTPGSHGSTFGGNPLACRVGCTVIDIIERQVLVENAALQGRQLLEGLRTALGAH
PNVLEVRGQGLMIGIELRQAIPELTRIAAEQHGLLINVTRGKIIRLLPPLVLDAAEVGQIVQGLTASLDSACDRSFARSA
>Mature_399_residues
TATCLMSTYQPLALSFTHGLGTRLWDHSGREYLDAVAGVAVTNVGHSHPLLVEAIRDQAGLLLHTSNLYTIDWQKRLAQK
LTALSGLDAVFFNNSGAEANETALKLARLHGWHKYIERPLVVVMENAFHGRTLGTLSASDGPAVRLGFSTLPGDYIKVPF
GDLAAFDKVCTTYGHRICAVLVEPIQGEGGAQVAPAGYLKALRERCTRRDWLLMLDEIQTGMGRTGKWFAFQHEGIVPDV
MTLAKGLGNGIPIGACLARGRAAQLFTPGSHGSTFGGNPLACRVGCTVIDIIERQVLVENAALQGRQLLEGLRTALGAHP
NVLEVRGQGLMIGIELRQAIPELTRIAAEQHGLLINVTRGKIIRLLPPLVLDAAEVGQIVQGLTASLDSACDRSFARSA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=35.8778625954198, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI284507298, Length=307, Percent_Identity=37.4592833876222, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI24119277, Length=409, Percent_Identity=32.2738386308068, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI13994255, Length=421, Percent_Identity=30.4038004750594, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI37574042, Length=398, Percent_Identity=30.4020100502513, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI226442705, Length=397, Percent_Identity=28.9672544080605, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=29.8941798941799, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI188536080, Length=412, Percent_Identity=25.9708737864078, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=412, Percent_Identity=25.9708737864078, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=412, Percent_Identity=25.9708737864078, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=40.1574803149606, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=39.8009950248756, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=37.0843989769821, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=34.0153452685422, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789016, Length=400, Percent_Identity=30.75, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1786991, Length=404, Percent_Identity=31.1881188118812, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=28.6144578313253, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=34.8404255319149, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=34.338747099768, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=261, Percent_Identity=36.0153256704981, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=30.3398058252427, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=32.7044025157233, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=381, Percent_Identity=24.4094488188976, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=381, Percent_Identity=37.2703412073491, Blast_Score=229, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=34.8258706467662, Blast_Score=222, Evalue=8e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=420, Percent_Identity=27.6190476190476, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=436, Percent_Identity=24.3119266055046, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=36.0313315926893, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI161085790, Length=454, Percent_Identity=30.3964757709251, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI28574759, Length=428, Percent_Identity=30.607476635514, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=29.0476190476191, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI281366494, Length=376, Percent_Identity=24.468085106383, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24667139, Length=376, Percent_Identity=24.468085106383, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24667143, Length=376, Percent_Identity=24.468085106383, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42988; Mature: 42857

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATCLMSTYQPLALSFTHGLGTRLWDHSGREYLDAVAGVAVTNVGHSHPLLVEAIRDQA
CCCHHHHHCCCCHHEEEHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
GLLLHTSNLYTIDWQKRLAQKLTALSGLDAVFFNNSGAEANETALKLARLHGWHKYIERP
CEEEEECCEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LVVVMENAFHGRTLGTLSASDGPAVRLGFSTLPGDYIKVPFGDLAAFDKVCTTYGHRICA
EEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHEEE
VLVEPIQGEGGAQVAPAGYLKALRERCTRRDWLLMLDEIQTGMGRTGKWFAFQHEGIVPD
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
VMTLAKGLGNGIPIGACLARGRAAQLFTPGSHGSTFGGNPLACRVGCTVIDIIERQVLVE
HHHHHHHCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
NAALQGRQLLEGLRTALGAHPNVLEVRGQGLMIGIELRQAIPELTRIAAEQHGLLINVTR
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCEEEEECC
GKIIRLLPPLVLDAAEVGQIVQGLTASLDSACDRSFARSA
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATCLMSTYQPLALSFTHGLGTRLWDHSGREYLDAVAGVAVTNVGHSHPLLVEAIRDQA
CCHHHHHCCCCHHEEEHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
GLLLHTSNLYTIDWQKRLAQKLTALSGLDAVFFNNSGAEANETALKLARLHGWHKYIERP
CEEEEECCEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LVVVMENAFHGRTLGTLSASDGPAVRLGFSTLPGDYIKVPFGDLAAFDKVCTTYGHRICA
EEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHEEE
VLVEPIQGEGGAQVAPAGYLKALRERCTRRDWLLMLDEIQTGMGRTGKWFAFQHEGIVPD
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
VMTLAKGLGNGIPIGACLARGRAAQLFTPGSHGSTFGGNPLACRVGCTVIDIIERQVLVE
HHHHHHHCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
NAALQGRQLLEGLRTALGAHPNVLEVRGQGLMIGIELRQAIPELTRIAAEQHGLLINVTR
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCEEEEECC
GKIIRLLPPLVLDAAEVGQIVQGLTASLDSACDRSFARSA
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]