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The map label for this gene is hlyB [H]

Identifier: 66045555

GI number: 66045555

Start: 2690686

End: 2692647

Strand: Direct

Name: hlyB [H]

Synonym: Psyr_2315

Alternate gene names: 66045555

Gene position: 2690686-2692647 (Clockwise)

Preceding gene: 66045554

Following gene: 66045556

Centisome position: 44.16

GC content: 58.87

Gene sequence:

>1962_bases
ATGCTTAGAAATGCTCCTTTGAGTATGAAACTGCTGCTTATTTTAATATTCCCCCTATTGGGCTTCCTGGCCTTCGCAGG
TCTGTTCGTTGCTGACAAAAGCGAAAATCTCGGTGATATGAGGCGCGCGGTGACAGCCACCGCGGTTGCACAGAAACTGA
GTAACGTGGTCACCACCATTCAGCGTGAGCGCGGCGCCAGCGGCGTGTTTCTGGGCAGCGGCGGCAAGTCCATGCAGGAT
AAGCTGAAGGCCTTTCGTCAGGAAACCGACAAGGCGATAAGCGAGATGCGCACCCAGTCGACCGACGGTATTCCCAGCCC
CGACAAAGTCTACCGCGCACTGGATGACCTGACCGCGCTGCGCCTCAAGATCGATACGCTGGGGATCAACAACACCGAGT
CCTCTACGCGGTTCACCGACGTTATCAAAACACTCGTCGGGTTCTCCTATTCGCTGGAAGCGAGTATCGAAGATCCGGAA
ATACTGCGTGGCCTGAGTTCGCTCAACCAGTTCGTGGATATGAAGGAGCGTGCCGGTCGCGAGCGCGTACTGCTCGTTCA
GGCGTTCAACCAGAACCGCTTTGATGCGCCACTGTTATCGCGCTTCAGTCGTAACCTCGGAGAGTTCTCCGGCTACCTCG
AAGCCTTTCAACGCTGGTCCCCTGAAGTATTCAAGACCAAACTCAATGATGTCATGCAGCAGCCGGGCTCGCTGGAAGTG
GCCCGCTTGCAACGTCTGGGCTTCGATACCCCGATGGGTGATCCGCTCAACGTCAAGCCGGAAGACTGGTTCAACCTTTC
CACCGCACGTATCGACATGATGGCCAATGTAGAAGCAGAGCTTGGCCAGAACGTCGTCGGCCTGGCAACGGATGCGCGCA
GCTCCGCTCAAAGCAGCCTGTACGTGGCGGTTGCCATCGTTGTCCTGATGCTGATCGTGGTGCTGTGGCTGGCGTCGGTG
ATCATCCGCAACATCAAGGTTGCGGTTGTCGACGTGAACCGCACGCTGATGGCACTTTCCACTCGCGACCTGACCGCGCG
GACCCGCTATATCGGCAAGGATGAGTTTGGCGAGATCTCACGCAATCTTGACAACATGGCGCATCAGATCAGTGAGGTTA
TCAGCGAAATCGGCAGCGCCACGGCGCAGGTTGCCACCGCTGCCGAACAGTCTTCCGCAGTGGCGTTGCAAACCAATCAG
AACGTGGCGCAACAACGCCAGGGTACCGATCAGGTCGCTACTGCCATCAGCGAGATGAGCGCCACGGTCAAGGATGTCGC
GCGCAGCACCACCGACGCGGCCGAGATGTCGCAACGCGTCAACAGCAGCACCGTGCAGGGCAAGACCGAAATCGACAACA
CCATCGGCCTGATTCAGGAGCTCTCGGTGCAGGCTGAAGAGACTTCACGGATCATCGACGAGCTCAAGGGCGAGAGCAAC
TCGATTTCTTCGGTGCTCGATGTCATTCGTGGTGTCGCCGACCAGACCAACCTGCTGGCGCTCAACGCAGCCATCGAGGC
TGCACGTGCCGGCGAGCAGGGGCGTGGTTTCGCGGTGGTGGCCGACGAAGTACGCAATCTGGCCAAGAAGACTCAGGACT
CTACCGTCAGCATCCAGAAAATGATCGCCAACCTGCAGTCCGGCTCGGAACGCGCTGCCGCGTCGATGCAGGAAACCCTG
GGCAAGGCGCAGGAGGGTGCCAGCAACGTCGTGCGCGCTGGCGAACTGCTGGAAGAAATCGCTGAAGGCATCGCGACCAT
CAGCGACCGCAACATCCAGGTCGCTTCGGCCGCTGAAGAACAAAGCCTGGTGGCCGAGGAGATCCACCGCAACGTCGACG
ACATCAACTCGCTGGTCATCCAGGTCAGTGCCGGTGCCGAGCAGACAGCGGTCACGAGTCGTGAACTGGCCAGGCTTGCT
GAGCAGCAGCAGGGGCTGGTGGGACGGTTTAAAGTGAGCTGA

Upstream 100 bases:

>100_bases
GATTACCGAACAGTCCCTGGCGACAAAAAAACGTCGACGCTACAGAACGTTACGCCCTGGATATTCTTTATAGAAAAGTC
TGCATGTCATGAGGTCTGCA

Downstream 100 bases:

>100_bases
CGATAAGGGGTTTGTTGGGTGTTCAGAGGCCTGGGAGCGTTAGCTCTCGGGCTTTTTTGTAGTGGTTGTCGGGCGGCAGG
AATTCGAGTGGCAGTTCTTG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MLRNAPLSMKLLLILIFPLLGFLAFAGLFVADKSENLGDMRRAVTATAVAQKLSNVVTTIQRERGASGVFLGSGGKSMQD
KLKAFRQETDKAISEMRTQSTDGIPSPDKVYRALDDLTALRLKIDTLGINNTESSTRFTDVIKTLVGFSYSLEASIEDPE
ILRGLSSLNQFVDMKERAGRERVLLVQAFNQNRFDAPLLSRFSRNLGEFSGYLEAFQRWSPEVFKTKLNDVMQQPGSLEV
ARLQRLGFDTPMGDPLNVKPEDWFNLSTARIDMMANVEAELGQNVVGLATDARSSAQSSLYVAVAIVVLMLIVVLWLASV
IIRNIKVAVVDVNRTLMALSTRDLTARTRYIGKDEFGEISRNLDNMAHQISEVISEIGSATAQVATAAEQSSAVALQTNQ
NVAQQRQGTDQVATAISEMSATVKDVARSTTDAAEMSQRVNSSTVQGKTEIDNTIGLIQELSVQAEETSRIIDELKGESN
SISSVLDVIRGVADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAKKTQDSTVSIQKMIANLQSGSERAAASMQETL
GKAQEGASNVVRAGELLEEIAEGIATISDRNIQVASAAEEQSLVAEEIHRNVDDINSLVIQVSAGAEQTAVTSRELARLA
EQQQGLVGRFKVS

Sequences:

>Translated_653_residues
MLRNAPLSMKLLLILIFPLLGFLAFAGLFVADKSENLGDMRRAVTATAVAQKLSNVVTTIQRERGASGVFLGSGGKSMQD
KLKAFRQETDKAISEMRTQSTDGIPSPDKVYRALDDLTALRLKIDTLGINNTESSTRFTDVIKTLVGFSYSLEASIEDPE
ILRGLSSLNQFVDMKERAGRERVLLVQAFNQNRFDAPLLSRFSRNLGEFSGYLEAFQRWSPEVFKTKLNDVMQQPGSLEV
ARLQRLGFDTPMGDPLNVKPEDWFNLSTARIDMMANVEAELGQNVVGLATDARSSAQSSLYVAVAIVVLMLIVVLWLASV
IIRNIKVAVVDVNRTLMALSTRDLTARTRYIGKDEFGEISRNLDNMAHQISEVISEIGSATAQVATAAEQSSAVALQTNQ
NVAQQRQGTDQVATAISEMSATVKDVARSTTDAAEMSQRVNSSTVQGKTEIDNTIGLIQELSVQAEETSRIIDELKGESN
SISSVLDVIRGVADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAKKTQDSTVSIQKMIANLQSGSERAAASMQETL
GKAQEGASNVVRAGELLEEIAEGIATISDRNIQVASAAEEQSLVAEEIHRNVDDINSLVIQVSAGAEQTAVTSRELARLA
EQQQGLVGRFKVS
>Mature_653_residues
MLRNAPLSMKLLLILIFPLLGFLAFAGLFVADKSENLGDMRRAVTATAVAQKLSNVVTTIQRERGASGVFLGSGGKSMQD
KLKAFRQETDKAISEMRTQSTDGIPSPDKVYRALDDLTALRLKIDTLGINNTESSTRFTDVIKTLVGFSYSLEASIEDPE
ILRGLSSLNQFVDMKERAGRERVLLVQAFNQNRFDAPLLSRFSRNLGEFSGYLEAFQRWSPEVFKTKLNDVMQQPGSLEV
ARLQRLGFDTPMGDPLNVKPEDWFNLSTARIDMMANVEAELGQNVVGLATDARSSAQSSLYVAVAIVVLMLIVVLWLASV
IIRNIKVAVVDVNRTLMALSTRDLTARTRYIGKDEFGEISRNLDNMAHQISEVISEIGSATAQVATAAEQSSAVALQTNQ
NVAQQRQGTDQVATAISEMSATVKDVARSTTDAAEMSQRVNSSTVQGKTEIDNTIGLIQELSVQAEETSRIIDELKGESN
SISSVLDVIRGVADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAKKTQDSTVSIQKMIANLQSGSERAAASMQETL
GKAQEGASNVVRAGELLEEIAEGIATISDRNIQVASAAEEQSLVAEEIHRNVDDINSLVIQVSAGAEQTAVTSRELARLA
EQQQGLVGRFKVS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=307, Percent_Identity=28.9902280130293, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1787690, Length=339, Percent_Identity=26.2536873156342, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=251, Percent_Identity=27.8884462151394, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=447, Percent_Identity=23.0425055928412, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=26.0736196319018, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70746; Mature: 70746

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNAPLSMKLLLILIFPLLGFLAFAGLFVADKSENLGDMRRAVTATAVAQKLSNVVTTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRERGASGVFLGSGGKSMQDKLKAFRQETDKAISEMRTQSTDGIPSPDKVYRALDDLTAL
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RLKIDTLGINNTESSTRFTDVIKTLVGFSYSLEASIEDPEILRGLSSLNQFVDMKERAGR
HEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
ERVLLVQAFNQNRFDAPLLSRFSRNLGEFSGYLEAFQRWSPEVFKTKLNDVMQQPGSLEV
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
ARLQRLGFDTPMGDPLNVKPEDWFNLSTARIDMMANVEAELGQNVVGLATDARSSAQSSL
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCEEEEECCCHHHHHHHH
YVAVAIVVLMLIVVLWLASVIIRNIKVAVVDVNRTLMALSTRDLTARTRYIGKDEFGEIS
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHCCCCHHHHHH
RNLDNMAHQISEVISEIGSATAQVATAAEQSSAVALQTNQNVAQQRQGTDQVATAISEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCHHHHHHHHHHHH
ATVKDVARSTTDAAEMSQRVNSSTVQGKTEIDNTIGLIQELSVQAEETSRIIDELKGESN
HHHHHHHHCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SISSVLDVIRGVADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAKKTQDSTVSIQK
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHH
MIANLQSGSERAAASMQETLGKAQEGASNVVRAGELLEEIAEGIATISDRNIQVASAAEE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
QSLVAEEIHRNVDDINSLVIQVSAGAEQTAVTSRELARLAEQQQGLVGRFKVS
HHHHHHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MLRNAPLSMKLLLILIFPLLGFLAFAGLFVADKSENLGDMRRAVTATAVAQKLSNVVTTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRERGASGVFLGSGGKSMQDKLKAFRQETDKAISEMRTQSTDGIPSPDKVYRALDDLTAL
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RLKIDTLGINNTESSTRFTDVIKTLVGFSYSLEASIEDPEILRGLSSLNQFVDMKERAGR
HEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
ERVLLVQAFNQNRFDAPLLSRFSRNLGEFSGYLEAFQRWSPEVFKTKLNDVMQQPGSLEV
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
ARLQRLGFDTPMGDPLNVKPEDWFNLSTARIDMMANVEAELGQNVVGLATDARSSAQSSL
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCEEEEECCCHHHHHHHH
YVAVAIVVLMLIVVLWLASVIIRNIKVAVVDVNRTLMALSTRDLTARTRYIGKDEFGEIS
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHCCCCHHHHHH
RNLDNMAHQISEVISEIGSATAQVATAAEQSSAVALQTNQNVAQQRQGTDQVATAISEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCHHHHHHHHHHHH
ATVKDVARSTTDAAEMSQRVNSSTVQGKTEIDNTIGLIQELSVQAEETSRIIDELKGESN
HHHHHHHHCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SISSVLDVIRGVADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAKKTQDSTVSIQK
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHH
MIANLQSGSERAAASMQETLGKAQEGASNVVRAGELLEEIAEGIATISDRNIQVASAAEE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
QSLVAEEIHRNVDDINSLVIQVSAGAEQTAVTSRELARLAEQQQGLVGRFKVS
HHHHHHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]