Click here to switch to the map view.

The map label for this gene is soxB [H]

Identifier: 66045464

GI number: 66045464

Start: 2585630

End: 2586871

Strand: Reverse

Name: soxB [H]

Synonym: Psyr_2224

Alternate gene names: 66045464

Gene position: 2586871-2585630 (Counterclockwise)

Preceding gene: 66045465

Following gene: 66045463

Centisome position: 42.45

GC content: 62.0

Gene sequence:

>1242_bases
ATGCCTTTCAACCTATTGAAATACGGGCTCAGCTCGCAGTACCCGGTCGAGGTGGATCTGCCTGCGCCCAAGGAACTGAA
GTCCTCCTACGACGTGGTGATCATCGGCGGCGGCGGGCATGGCCTGGCCACCGCTTACTACCTGTCGAAATACCACGGCA
TCACTAATATTGCTGTGCTGGAAAAAGGTTACCTGGGCGGCGGCAATACGGCACGCAACACGGCGGTGATCCGCTCCAAT
TACCTGACCAGCGAAGGCGTGAAGTTCTATACCGAGTCGGTGAAGATGTTTCAGGGCCTGTCCAACGAGTTCGACTTCAA
CATCATGTACTCCGAGCGCGGCCAACTGACCCTGGCGCACACCGACGCCACGGTCAGGTCGTTCCGCCAGCGCGCCGAGG
TCAACAAGCATTTCGGTGGCCGCACCGAGATGATCGACCGCCAGCAGATCCGCGAGCTGGTGCCGAGCCTCAATCTGGAC
CCCGGCCATCTGCCGGTGCTCGCCGGCCTGTGGCACATCGACGGTGGCACCGCCCGGCATGACGCGGTCGCCTGGGGTTA
CGCCAGGCAGGCGGCCAAGCGTGGAGTGGAGATTCATCAACTGACCGAAGTGCAGGAACTAGTGATCGAGAACGGCACCC
TCACTGCGGTGAAGACCAATCGCGGCACCATCCAGTGCGGCTGCGCCGTGCAGGCGGTGGCGGGCATGAGTTCGCAGATG
ATGAAGAAAGCCGGGATCCGCTCGCCGATCCAGACCTTCCCGTTGCAGGCGATGGTCACGCAACCCTTCAAGCCGTTCCT
CGACCCGCTGGTGAGTTCGTCCGCCCTGCACTGCTATGTGCAGCAGACCAGCCGTGGCGAAGTGGTGTTTGGCGGTGGCT
CTGATCCCTACCCGTTGTTCAACAGCCGCTCGACGCTGGAGCTCAAGGAAAGCCTGCTGGCCCACGCCATCGAGATGTTT
CCGTTTCTGGCCAACGCCAAACTGATGCGCCAATGGGCCGGGATCACCGACATGACCCCGGATTACAGCCCGATCATGGG
CCTTTCGCCGGTCCGGAATTACTACCTGGACGCGGGCTGGGGCACCTGGGGCTTCAAGGCCACACCGATCTGCGGCAAGA
CCATGGCCGAACTGGTGGCCAGCGGCGGCAAAGTGCCCGAGTTGATCAGGCCGTTCGCGCTCGACCGCTTCTCGACCTTT
CAGCAAGTCAACGAAATGGGCGCAACAGCGGCCAGCCACTGA

Upstream 100 bases:

>100_bases
CCGGCGGAGTCGGCCCGATGACTATCGCCTTTCTGATGAAAAACACCGTGACTGCTGCCCGGCAGCAGGCCCACGCGCAA
CGCAGCCAACCGGAGGCCGT

Downstream 100 bases:

>100_bases
CGGAGAGCGACACATGAAAATCATGACCTGCCCGCTCAACGGGCCGCGCAACATCAGCGAGTTCACCTACGGCGGAGAAT
TCAAACACATGCCCGACCCG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MPFNLLKYGLSSQYPVEVDLPAPKELKSSYDVVIIGGGGHGLATAYYLSKYHGITNIAVLEKGYLGGGNTARNTAVIRSN
YLTSEGVKFYTESVKMFQGLSNEFDFNIMYSERGQLTLAHTDATVRSFRQRAEVNKHFGGRTEMIDRQQIRELVPSLNLD
PGHLPVLAGLWHIDGGTARHDAVAWGYARQAAKRGVEIHQLTEVQELVIENGTLTAVKTNRGTIQCGCAVQAVAGMSSQM
MKKAGIRSPIQTFPLQAMVTQPFKPFLDPLVSSSALHCYVQQTSRGEVVFGGGSDPYPLFNSRSTLELKESLLAHAIEMF
PFLANAKLMRQWAGITDMTPDYSPIMGLSPVRNYYLDAGWGTWGFKATPICGKTMAELVASGGKVPELIRPFALDRFSTF
QQVNEMGATAASH

Sequences:

>Translated_413_residues
MPFNLLKYGLSSQYPVEVDLPAPKELKSSYDVVIIGGGGHGLATAYYLSKYHGITNIAVLEKGYLGGGNTARNTAVIRSN
YLTSEGVKFYTESVKMFQGLSNEFDFNIMYSERGQLTLAHTDATVRSFRQRAEVNKHFGGRTEMIDRQQIRELVPSLNLD
PGHLPVLAGLWHIDGGTARHDAVAWGYARQAAKRGVEIHQLTEVQELVIENGTLTAVKTNRGTIQCGCAVQAVAGMSSQM
MKKAGIRSPIQTFPLQAMVTQPFKPFLDPLVSSSALHCYVQQTSRGEVVFGGGSDPYPLFNSRSTLELKESLLAHAIEMF
PFLANAKLMRQWAGITDMTPDYSPIMGLSPVRNYYLDAGWGTWGFKATPICGKTMAELVASGGKVPELIRPFALDRFSTF
QQVNEMGATAASH
>Mature_412_residues
PFNLLKYGLSSQYPVEVDLPAPKELKSSYDVVIIGGGGHGLATAYYLSKYHGITNIAVLEKGYLGGGNTARNTAVIRSNY
LTSEGVKFYTESVKMFQGLSNEFDFNIMYSERGQLTLAHTDATVRSFRQRAEVNKHFGGRTEMIDRQQIRELVPSLNLDP
GHLPVLAGLWHIDGGTARHDAVAWGYARQAAKRGVEIHQLTEVQELVIENGTLTAVKTNRGTIQCGCAVQAVAGMSSQMM
KKAGIRSPIQTFPLQAMVTQPFKPFLDPLVSSSALHCYVQQTSRGEVVFGGGSDPYPLFNSRSTLELKESLLAHAIEMFP
FLANAKLMRQWAGITDMTPDYSPIMGLSPVRNYYLDAGWGTWGFKATPICGKTMAELVASGGKVPELIRPFALDRFSTFQ
QVNEMGATAASH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=399, Percent_Identity=27.3182957393484, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI197927446, Length=378, Percent_Identity=21.957671957672, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI21361378, Length=378, Percent_Identity=21.957671957672, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI24797151, Length=418, Percent_Identity=23.6842105263158, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20130091, Length=417, Percent_Identity=22.5419664268585, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45269; Mature: 45138

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNLLKYGLSSQYPVEVDLPAPKELKSSYDVVIIGGGGHGLATAYYLSKYHGITNIAVL
CCHHHHHHCCCCCCCEEEECCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEE
EKGYLGGGNTARNTAVIRSNYLTSEGVKFYTESVKMFQGLSNEFDFNIMYSERGQLTLAH
ECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEE
TDATVRSFRQRAEVNKHFGGRTEMIDRQQIRELVPSLNLDPGHLPVLAGLWHIDGGTARH
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEHEEECCCCCCCH
DAVAWGYARQAAKRGVEIHQLTEVQELVIENGTLTAVKTNRGTIQCGCAVQAVAGMSSQM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEECHHHHHHHCCHHHH
MKKAGIRSPIQTFPLQAMVTQPFKPFLDPLVSSSALHCYVQQTSRGEVVFGGGSDPYPLF
HHHHCCCCCHHHCCHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCEEECCCCCCCCCC
NSRSTLELKESLLAHAIEMFPFLANAKLMRQWAGITDMTPDYSPIMGLSPVRNYYLDAGW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEEECCC
GTWGFKATPICGKTMAELVASGGKVPELIRPFALDRFSTFQQVNEMGATAASH
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PFNLLKYGLSSQYPVEVDLPAPKELKSSYDVVIIGGGGHGLATAYYLSKYHGITNIAVL
CHHHHHHCCCCCCCEEEECCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEE
EKGYLGGGNTARNTAVIRSNYLTSEGVKFYTESVKMFQGLSNEFDFNIMYSERGQLTLAH
ECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEE
TDATVRSFRQRAEVNKHFGGRTEMIDRQQIRELVPSLNLDPGHLPVLAGLWHIDGGTARH
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEHEEECCCCCCCH
DAVAWGYARQAAKRGVEIHQLTEVQELVIENGTLTAVKTNRGTIQCGCAVQAVAGMSSQM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEECHHHHHHHCCHHHH
MKKAGIRSPIQTFPLQAMVTQPFKPFLDPLVSSSALHCYVQQTSRGEVVFGGGSDPYPLF
HHHHCCCCCHHHCCHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCEEECCCCCCCCCC
NSRSTLELKESLLAHAIEMFPFLANAKLMRQWAGITDMTPDYSPIMGLSPVRNYYLDAGW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEEECCC
GTWGFKATPICGKTMAELVASGGKVPELIRPFALDRFSTFQQVNEMGATAASH
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]