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The map label for this gene is aroF [H]

Identifier: 66045313

GI number: 66045313

Start: 2418254

End: 2419342

Strand: Reverse

Name: aroF [H]

Synonym: Psyr_2073

Alternate gene names: 66045313

Gene position: 2419342-2418254 (Counterclockwise)

Preceding gene: 66045318

Following gene: 66045311

Centisome position: 39.7

GC content: 60.15

Gene sequence:

>1089_bases
ATGAGTAACACGATGGCTGATTTACCGATTGACGACCTCAACGTTGCCTCCAACGAGACTCTGATCACTCCGGATCAGCT
CAAGCGCGACATCCCCCTGACCGATGCTGCCCTGCAGACCGTCAGCCAGGGCCGCGAAGTGATTCGCAACATTCTCGATG
GCCATGACCACCGCCTGTTCATCGTGATCGGCCCGTGCTCGATCCACGACCTCAAGGCAGCCAAGGAGTACGCCGAGCGT
CTCAAGGCGCTGGCGGCGGAAGTGTCTGACACGCTGTATCTGGTGATGCGCGTCTACTTCGAGAAGCCGCGCACCACGGT
GGGCTGGAAAGGCCTGATCAACGACCCGTACCTGGATGACTCGTTCAAGATCCAGGATGGCCTGCACATCGGTCGCCAGT
TGCTGCTGGATCTGGCCGAGATGGGTCTGCCCACCGCCACCGAAGCCCTGGACCCGATCTCCCCGCAGTATCTGCAGGAC
CTGATCAGCTGGTCGGCAATCGGCGCGCGCACCACAGAATCCCAGACTCACCGCGAGATGGCTTCGGGCCTGTCCTCGGC
AGTCGGTTTCAAGAACGGTACCGACGGCGGCCTGACGGTTGCCATCAACGCCTTGCAATCGGTGTCGAGCCCGCATCGTT
TCCTGGGTATCAACCAGGAAGGCGGCGTGTCGATCGTGACCACCAAAGGCAATGCCTACGGTCATGTGGTGCTGCGCGGC
GGCAACGGCAAGCCCAACTATGACTCGGTCAGCGTTGCGCTCTGCGAGCAGGCGCTGAACAAGTCCGGCATTCGCCCGAA
CATCATGGTCGACTGCAGCCATGCCAACTCCAACAAGGACCCGGCGCTGCAACCGCTGGTGATGGAAAACGTCGCCAACC
AGATCCTGGAAGGCAACGAATCGATCATCGGCCTGATGGTCGAGAGCCATTTGAACTGGGGCTGCCAGGCGATTCCCAAG
GACCTGTCGGAATTGCAGTACGGCGTGTCGATTACCGATGCCTGCATCGATTGGCAAAGCACTGAAAAGACCCTGCGCAG
CATGCACGCGAAACTCAAGGATGTGCTGCCAGCTCGCAAGCGCAAGTAA

Upstream 100 bases:

>100_bases
GAACAGCGCGATAACGCGCTAAGGTTCGGCTCCCCGCTGCGCTCAAACCAGCTGGACACCGCCGCACGGGGGACCGTTGG
CGGCCAGTACCCGCGACCTG

Downstream 100 bases:

>100_bases
TTGCCTGACGGACTGCACTGCAATAACGAAAACGCCGAGCAAATGCTCGGCGTTTTTTTATGCTGACTGTCGGTAGCTAC
AGGTCGTCAGAGCTTGGCGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSNTMADLPIDDLNVASNETLITPDQLKRDIPLTDAALQTVSQGREVIRNILDGHDHRLFIVIGPCSIHDLKAAKEYAER
LKALAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQD
LISWSAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRG
GNGKPNYDSVSVALCEQALNKSGIRPNIMVDCSHANSNKDPALQPLVMENVANQILEGNESIIGLMVESHLNWGCQAIPK
DLSELQYGVSITDACIDWQSTEKTLRSMHAKLKDVLPARKRK

Sequences:

>Translated_362_residues
MSNTMADLPIDDLNVASNETLITPDQLKRDIPLTDAALQTVSQGREVIRNILDGHDHRLFIVIGPCSIHDLKAAKEYAER
LKALAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQD
LISWSAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRG
GNGKPNYDSVSVALCEQALNKSGIRPNIMVDCSHANSNKDPALQPLVMENVANQILEGNESIIGLMVESHLNWGCQAIPK
DLSELQYGVSITDACIDWQSTEKTLRSMHAKLKDVLPARKRK
>Mature_361_residues
SNTMADLPIDDLNVASNETLITPDQLKRDIPLTDAALQTVSQGREVIRNILDGHDHRLFIVIGPCSIHDLKAAKEYAERL
KALAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQDL
ISWSAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGG
NGKPNYDSVSVALCEQALNKSGIRPNIMVDCSHANSNKDPALQPLVMENVANQILEGNESIIGLMVESHLNWGCQAIPKD
LSELQYGVSITDACIDWQSTEKTLRSMHAKLKDVLPARKRK

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=350, Percent_Identity=59.4285714285714, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1786969, Length=343, Percent_Identity=54.5189504373178, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1787996, Length=338, Percent_Identity=47.3372781065089, Blast_Score=322, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6319726, Length=352, Percent_Identity=49.4318181818182, Blast_Score=348, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6320240, Length=358, Percent_Identity=46.927374301676, Blast_Score=336, Evalue=4e-93,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39462; Mature: 39331

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTMADLPIDDLNVASNETLITPDQLKRDIPLTDAALQTVSQGREVIRNILDGHDHRLF
CCCCCCCCCCCCCCCCCCCCEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
IVIGPCSIHDLKAAKEYAERLKALAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDD
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREM
CCEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
ASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRG
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEEC
GNGKPNYDSVSVALCEQALNKSGIRPNIMVDCSHANSNKDPALQPLVMENVANQILEGNE
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
SIIGLMVESHLNWGCQAIPKDLSELQYGVSITDACIDWQSTEKTLRSMHAKLKDVLPARK
CEEEEEEHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
RK
CC
>Mature Secondary Structure 
SNTMADLPIDDLNVASNETLITPDQLKRDIPLTDAALQTVSQGREVIRNILDGHDHRLF
CCCCCCCCCCCCCCCCCCCEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
IVIGPCSIHDLKAAKEYAERLKALAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDD
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFKIQDGLHIGRQLLLDLAEMGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREM
CCEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
ASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRG
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEEC
GNGKPNYDSVSVALCEQALNKSGIRPNIMVDCSHANSNKDPALQPLVMENVANQILEGNE
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
SIIGLMVESHLNWGCQAIPKDLSELQYGVSITDACIDWQSTEKTLRSMHAKLKDVLPARK
CEEEEEEHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
RK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]