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The map label for this gene is insK [H]

Identifier: 66045215

GI number: 66045215

Start: 2292586

End: 2293392

Strand: Reverse

Name: insK [H]

Synonym: Psyr_1975

Alternate gene names: 66045215

Gene position: 2293392-2292586 (Counterclockwise)

Preceding gene: 66045216

Following gene: 66045213

Centisome position: 37.64

GC content: 53.28

Gene sequence:

>807_bases
ATGTGCGCCCTTCTGACGCTGGCGGGCCTGGCGCGCAGCACGTTTTACTATCAGGCTCAGGTGCAATCCAGACCCGATCC
AGATGCTGCTCTAAAGCAGGAGATAGAGCGGATTTATCACGAGGAGAGAGGTCTTTATGGAGCTCGGCGCATCACGGCGG
TTATCCGCAACTCAGGCACGTTGGTCAACAAGAAGGTTGTGGAGCGATTGATGGCTGAATTGGGCCTGAGATCAGTTGTG
CGACCCAAGAAGTACCGCTCCTATAAGGGCACCGTCGGGAAAATTGCGCCGAATTTGCTGGAGCGCAAGTTCACGGCGCA
ACGCCCGAACCAGAAATGGGTGACCGATGTGACAGAGTTTAAAGTGGCCAATCGAAAGCTGTATCTCTCGCCCGTGATGG
ACCTGTACAACGGTGAGATCGTGGCGTACGAAGTGTCTACCAGGCCGTGCTTCGAGCTGGTCACCAATATGCTGGACAAG
GCTCTCCAGCAGTTGCAGGACGAGCCGAAGCTTGTGATGCACTCGGATCAGGGCTGGCAGTATCAACACGCGCAGTACCG
TCAGAAACTGGCGGTAAAGGGTGTAAAGCAAAGCATGTCTCGTAAGGGAAATTGCCTGGACAATGCCGCAATGGAAAGCT
TCTTTGGTACGCTGAAGTCCGAGTTTTTCTATTTGAAACGATTTGAAAGCATAGAAGAGCTGAAGGCAGGTCTGGATGAG
TACATCCGCTACTACAACAATGACCGCATCAAGCTGAAGCTAAACGGCTTGAGCCCCGTAAAATACAGGGCTCAGGCGGC
GAGCTAA

Upstream 100 bases:

>100_bases
TGGAGAACGCTTACCTAAAAAAGTTGGAAGAGTTGAAGGAGCAGCAACGACGGCAAAAGAAAAAGCCCTGATCGTCAAAC
AACTGAGGAACCGGTTTCCG

Downstream 100 bases:

>100_bases
AACTGTCCAACTTTCGGGGGGCAGTCCACCGCGTGGGAATGCAGTTCGTGACGCTCCGCGTCACACGGCAGTTCTGTCAG
GTGGATTGAGATTTGACAAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERIYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNNDRIKLKLNGLSPVKYRAQAAS

Sequences:

>Translated_268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERIYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNNDRIKLKLNGLSPVKYRAQAAS
>Mature_268_residues
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERIYHEERGLYGARRITAVIRNSGTLVNKKVVERLMAELGLRSVV
RPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEFKVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDK
ALQQLQDEPKLVMHSDQGWQYQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
YIRYYNNDRIKLKLNGLSPVKYRAQAAS

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=30.4721030042918, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1789981, Length=263, Percent_Identity=55.5133079847909, Blast_Score=313, Evalue=7e-87,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30926; Mature: 30926

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERIYHEERGLYGARRITAVIRNSGT
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LVNKKVVERLMAELGLRSVVRPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEF
CHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDKALQQLQDEPKLVMHSDQGWQ
HHHCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
YQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRYYNNDRIKLKLNGLSPVKYRAQAAS
HHHHHCCCEEEEEECCCCCHHHHCCCCC
>Mature Secondary Structure
MCALLTLAGLARSTFYYQAQVQSRPDPDAALKQEIERIYHEERGLYGARRITAVIRNSGT
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LVNKKVVERLMAELGLRSVVRPKKYRSYKGTVGKIAPNLLERKFTAQRPNQKWVTDVTEF
CHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KVANRKLYLSPVMDLYNGEIVAYEVSTRPCFELVTNMLDKALQQLQDEPKLVMHSDQGWQ
HHHCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
YQHAQYRQKLAVKGVKQSMSRKGNCLDNAAMESFFGTLKSEFFYLKRFESIEELKAGLDE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRYYNNDRIKLKLNGLSPVKYRAQAAS
HHHHHCCCEEEEEECCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]