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The map label for this gene is aspC [H]

Identifier: 66045213

GI number: 66045213

Start: 2288809

End: 2290005

Strand: Reverse

Name: aspC [H]

Synonym: Psyr_1973

Alternate gene names: 66045213

Gene position: 2290005-2288809 (Counterclockwise)

Preceding gene: 66045215

Following gene: 66045212

Centisome position: 37.58

GC content: 61.74

Gene sequence:

>1197_bases
ATGAGCCTGTTTTCCGCTGTCGAAATGGCACCCCGCGATCCGATCCTGGGTATCAACGAAGCCTTCAACGCCGACACCCG
CAGCACCAAGGTCAACCTTGGCGTAGGCGTCTACTGTGATGAAGACGGGCGCATCCCCCTGCTGCGCGCCGTGGCCGAAG
CCGAGAAGGTCCGCGTGGCCCAGCATGCTCCGCGCGGCTACCTGCCGATCGACGGTATTGCCGCCTATGACCAGGCTGTG
CAAAAACTGTTGCTGGGCGCTGATTCGCCGCTGATCGCCTCGGGCCGCGTGCTGACCACCCAATCGGTCGGCGGCACCGG
CGCACTGAAGATCGGTGCCGACTTCCTCAAGCAGCTGCTGCCCGATGCCGTCGTCGCCATCAGCGACCCGAGCTGGGAAA
ACCACCGTGCGCTGTTCGAAACCGCAGGCTTTGCGGTGCAGAACTATCGCTACTACGACGCTGCCACTCACGACGTGAAC
CGTGCCGGCATGCTCGAAGACCTGCACAACCTGCCGAACAACTCGGTGGTGGTGTTGCATGCCTGCTGCCACAACCCGAC
CGGCGTCGACCTGAGCCTGGATGACTGGAAGAAAGTGCTGGAAGTGGTCAAGGCCAAGGGCCACGTACCGTTTCTGGACA
TGGCCTACCAAGGCTTCGGTCAGGGTATTCAGGAAGATGCGCTGGCAGTGCGCCTGTTTGCCGAGTCGGGCCTGACCTTC
TTCGCCTCCAGCTCGTTCTCCAAATCGCTGTCGCTGTATGGCGAACGCGTCGGCGCGCTGTCGATCATCACCGAATCGAA
GGAAGAAACCACTCGCGTCCTGTCCCAGGTCAAACGCGTGATCCGTACCAACTACTCCAACCCGCCGACCCACGGTGCGA
TCATCTCCGCTGCGGTGCTTAACGACCCGACGTTGCGTGCAATGTGGGAAGAGGAACTAGGCGAAATGCGTCTGCGCATC
CAGGGCATGCGCAAGGCGATGGTCGAGCGTCTGGCTGATAACCCGGCCGGTCAGGACTTCAGCTTCGTCGCTCGCCAGTG
CGGCATGTTTTCCTACTCCGGCCTGACCGCCGAACAGGCCCAGCGCCTGCGCAGCGAGTTCGGCATCTACGCGCTGGACA
CCGGGCGTATCTGCGTGGCCGCGCTGAATCAGAAGAACATCGACGTAGTGTGTGATGCGATCAAGCAGGTTCTTTAA

Upstream 100 bases:

>100_bases
CGAGGGGATGCTCTCTATACTACGCTCTGTTTGCGCACCGCTTTGGCGCATCGAGCCTCAGCGTGTCCCCTTCCCACTCT
TCACCAAGAGCCGCCGCACC

Downstream 100 bases:

>100_bases
GTTTTAAGCTGCAAGCTGCAAGCTGCAAGCTGCAAGCTGCAAGCTGCAAGCTGCAAGCTGCAAGCAAGAGCGGTTCTGCT
TTTTCTTGAAGCTTGTAGCT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLFSAVEMAPRDPILGINEAFNADTRSTKVNLGVGVYCDEDGRIPLLRAVAEAEKVRVAQHAPRGYLPIDGIAAYDQAV
QKLLLGADSPLIASGRVLTTQSVGGTGALKIGADFLKQLLPDAVVAISDPSWENHRALFETAGFAVQNYRYYDAATHDVN
RAGMLEDLHNLPNNSVVVLHACCHNPTGVDLSLDDWKKVLEVVKAKGHVPFLDMAYQGFGQGIQEDALAVRLFAESGLTF
FASSSFSKSLSLYGERVGALSIITESKEETTRVLSQVKRVIRTNYSNPPTHGAIISAAVLNDPTLRAMWEEELGEMRLRI
QGMRKAMVERLADNPAGQDFSFVARQCGMFSYSGLTAEQAQRLRSEFGIYALDTGRICVAALNQKNIDVVCDAIKQVL

Sequences:

>Translated_398_residues
MSLFSAVEMAPRDPILGINEAFNADTRSTKVNLGVGVYCDEDGRIPLLRAVAEAEKVRVAQHAPRGYLPIDGIAAYDQAV
QKLLLGADSPLIASGRVLTTQSVGGTGALKIGADFLKQLLPDAVVAISDPSWENHRALFETAGFAVQNYRYYDAATHDVN
RAGMLEDLHNLPNNSVVVLHACCHNPTGVDLSLDDWKKVLEVVKAKGHVPFLDMAYQGFGQGIQEDALAVRLFAESGLTF
FASSSFSKSLSLYGERVGALSIITESKEETTRVLSQVKRVIRTNYSNPPTHGAIISAAVLNDPTLRAMWEEELGEMRLRI
QGMRKAMVERLADNPAGQDFSFVARQCGMFSYSGLTAEQAQRLRSEFGIYALDTGRICVAALNQKNIDVVCDAIKQVL
>Mature_397_residues
SLFSAVEMAPRDPILGINEAFNADTRSTKVNLGVGVYCDEDGRIPLLRAVAEAEKVRVAQHAPRGYLPIDGIAAYDQAVQ
KLLLGADSPLIASGRVLTTQSVGGTGALKIGADFLKQLLPDAVVAISDPSWENHRALFETAGFAVQNYRYYDAATHDVNR
AGMLEDLHNLPNNSVVVLHACCHNPTGVDLSLDDWKKVLEVVKAKGHVPFLDMAYQGFGQGIQEDALAVRLFAESGLTFF
ASSSFSKSLSLYGERVGALSIITESKEETTRVLSQVKRVIRTNYSNPPTHGAIISAAVLNDPTLRAMWEEELGEMRLRIQ
GMRKAMVERLADNPAGQDFSFVARQCGMFSYSGLTAEQAQRLRSEFGIYALDTGRICVAALNQKNIDVVCDAIKQVL

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=44.4444444444444, Blast_Score=347, Evalue=9e-96,
Organism=Homo sapiens, GI4504067, Length=405, Percent_Identity=40.2469135802469, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=27.0341207349081, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=50.6297229219144, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=45.2020202020202, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=41.2060301507538, Blast_Score=341, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=42.5692695214106, Blast_Score=341, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=38.3084577114428, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17569537, Length=396, Percent_Identity=31.5656565656566, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=43.6619718309859, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17550384, Length=268, Percent_Identity=33.955223880597, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.4532019704434, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=434, Percent_Identity=32.258064516129, Blast_Score=239, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=42.4623115577889, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=42.4623115577889, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=42.4552429667519, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24654046, Length=398, Percent_Identity=37.9396984924623, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI19922362, Length=398, Percent_Identity=37.9396984924623, Blast_Score=295, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43335; Mature: 43204

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVEMAPRDPILGINEAFNADTRSTKVNLGVGVYCDEDGRIPLLRAVAEAEKVRVA
CCHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QHAPRGYLPIDGIAAYDQAVQKLLLGADSPLIASGRVLTTQSVGGTGALKIGADFLKQLL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCHHHHHHHHHHHC
PDAVVAISDPSWENHRALFETAGFAVQNYRYYDAATHDVNRAGMLEDLHNLPNNSVVVLH
CCCEEEECCCCCCCHHHHHHHHCCCEECEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEE
ACCHNPTGVDLSLDDWKKVLEVVKAKGHVPFLDMAYQGFGQGIQEDALAVRLFAESGLTF
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHEEEEHHHCCCEE
FASSSFSKSLSLYGERVGALSIITESKEETTRVLSQVKRVIRTNYSNPPTHGAIISAAVL
EECCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
NDPTLRAMWEEELGEMRLRIQGMRKAMVERLADNPAGQDFSFVARQCGMFSYSGLTAEQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHH
QRLRSEFGIYALDTGRICVAALNQKNIDVVCDAIKQVL
HHHHHHCCEEEECCCCEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVEMAPRDPILGINEAFNADTRSTKVNLGVGVYCDEDGRIPLLRAVAEAEKVRVA
CHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QHAPRGYLPIDGIAAYDQAVQKLLLGADSPLIASGRVLTTQSVGGTGALKIGADFLKQLL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCHHHHHHHHHHHC
PDAVVAISDPSWENHRALFETAGFAVQNYRYYDAATHDVNRAGMLEDLHNLPNNSVVVLH
CCCEEEECCCCCCCHHHHHHHHCCCEECEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEE
ACCHNPTGVDLSLDDWKKVLEVVKAKGHVPFLDMAYQGFGQGIQEDALAVRLFAESGLTF
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHEEEEHHHCCCEE
FASSSFSKSLSLYGERVGALSIITESKEETTRVLSQVKRVIRTNYSNPPTHGAIISAAVL
EECCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
NDPTLRAMWEEELGEMRLRIQGMRKAMVERLADNPAGQDFSFVARQCGMFSYSGLTAEQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHH
QRLRSEFGIYALDTGRICVAALNQKNIDVVCDAIKQVL
HHHHHHCCEEEECCCCEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]