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The map label for this gene is 66045206

Identifier: 66045206

GI number: 66045206

Start: 2277546

End: 2278940

Strand: Reverse

Name: 66045206

Synonym: Psyr_1966

Alternate gene names: NA

Gene position: 2278940-2277546 (Counterclockwise)

Preceding gene: 66045208

Following gene: 66045205

Centisome position: 37.4

GC content: 61.43

Gene sequence:

>1395_bases
ATGACAAGACCGCGTTGGAAAAAAGCTCTCTTCATCGGCCTGCCGCTGGCCCTGGCCATCAGTGCAGGTGCGGGCTTTCT
GGCCTGGAATTACTGGTCGCCAGCAGGCTACCCGGTCAAGGTTATGCAACAGGCCGACGACCTGCAGGAGCGGATCATTT
CCTTCGACAGCCACATCACCGTGCCGATGAAATTCGGCAGCGAGGGCAACGAAGCCGACAAGGACGGCTCGGGGCAATTC
GACCTGGTGAAAGCCGCGCGCGGACGCCTGTCCGGGGCTGCACTGACGGTATTCGGCTGGCCGGAGATCTGGAACGGCGA
CAACGCCCCGCATCGTCCGACACCCGGTTTCGTCGACGAAGCACGCCATCAGCAGGAAGTGCGTTACAAAATCATCACCG
GCATGGTTCGCGACTTCCCCAATCAGGTCGGCATCGCCTACACCCCGGACGACATGCGCCGCCTGCACGGCGAAGGCAAG
TTTGCGATCTTCATCAGCATGCTCAACGCTTACCCGCTGGGCAATGACCTGAGCCTGCTGGACCACTGGACCGCACGCGG
CATGCGCATGTTCGGTTTCAGTTATGTCGGCAATAACAGCTGGGCCGACTCTTCACGTCCCCTGCCCTTTCTCAATGACA
CGCCCGACGCACTGGGCGGCCTGTCGGAGATCGGCAGGCAGGCAGTGCAACGCCTCAACGATCTGGGCGTGATCATCGAC
GTGTCACAGATGTCGAGCAAGGCGCTGCAACAGGTCAGCGAGCTGAGCCGCACGCCGATGGTCGCCTCGCACTCGACGCC
GCGTGCGCTGGTGGACATCCCGCGCAACCTCAGCGACGAGGAACTGCAGCTCATCAAGCGCAGCGGCGGCGTGGTACAGA
TCGTGGCGTTTCCGGCCTATTTGAAGCCGCTGAGCCAGAAGACCCAGGACAAGCTCAACGCGCTGCGCAAGGACTTCGAC
CTGCCGCCGTTGCCGAACCTGGCCATGGCACTGATGCCCGGCGACCCGATCATCACCGTCTGGCCGGAACAACGCTTCGG
CGCCTATGCCAGCAAGCTGTACGCGATTCTCGAGGAAGAGCCCAAAGCCACGGTCAAGGACTTCGTCGACGCCATCGATT
ACACCGTCCGCAAAATCGGCATCGACCACGTCGGCATCAGCTCCGACTTCAATGATGGCGGCGGTGTGAAAGGCTTCAAT
GATGTCAGCGAAATCCGCAACGTGACGGCCGAACTGATCGAGCGCGGCTATGCCGAAGCGGATATCACCAAGCTCTGGGG
CGGCAATTTCCTGCGCGTCTGGGAGCAGGTTCAGGCTGCTGCTCGTCCGGATATGAAGCACATGAATCTCTCAAACGCCG
CTACCCGACCCTCAGGCGCAGACGCTCATGACTGA

Upstream 100 bases:

>100_bases
ATCCATGACCCCGCGCTAAATTTATCGGCGATCCGCTCGTTCTCCACCAGATAGCAACAGCCGTCGCAGGCTGCGCAACG
GTTAACCACACGAGACGGAA

Downstream 100 bases:

>100_bases
TCGCAGAACCTTCCTCAAACAGGCCGGGCTGCTCGCGGCAGCCCTGCCCCTGGGCTCCGGCCTTGCAACGGCAGCCGTGA
CGCCAGCGACTCAGCCGGCC

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF R [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTRPRWKKALFIGLPLALAISAGAGFLAWNYWSPAGYPVKVMQQADDLQERIISFDSHITVPMKFGSEGNEADKDGSGQF
DLVKAARGRLSGAALTVFGWPEIWNGDNAPHRPTPGFVDEARHQQEVRYKIITGMVRDFPNQVGIAYTPDDMRRLHGEGK
FAIFISMLNAYPLGNDLSLLDHWTARGMRMFGFSYVGNNSWADSSRPLPFLNDTPDALGGLSEIGRQAVQRLNDLGVIID
VSQMSSKALQQVSELSRTPMVASHSTPRALVDIPRNLSDEELQLIKRSGGVVQIVAFPAYLKPLSQKTQDKLNALRKDFD
LPPLPNLAMALMPGDPIITVWPEQRFGAYASKLYAILEEEPKATVKDFVDAIDYTVRKIGIDHVGISSDFNDGGGVKGFN
DVSEIRNVTAELIERGYAEADITKLWGGNFLRVWEQVQAAARPDMKHMNLSNAATRPSGADAHD

Sequences:

>Translated_464_residues
MTRPRWKKALFIGLPLALAISAGAGFLAWNYWSPAGYPVKVMQQADDLQERIISFDSHITVPMKFGSEGNEADKDGSGQF
DLVKAARGRLSGAALTVFGWPEIWNGDNAPHRPTPGFVDEARHQQEVRYKIITGMVRDFPNQVGIAYTPDDMRRLHGEGK
FAIFISMLNAYPLGNDLSLLDHWTARGMRMFGFSYVGNNSWADSSRPLPFLNDTPDALGGLSEIGRQAVQRLNDLGVIID
VSQMSSKALQQVSELSRTPMVASHSTPRALVDIPRNLSDEELQLIKRSGGVVQIVAFPAYLKPLSQKTQDKLNALRKDFD
LPPLPNLAMALMPGDPIITVWPEQRFGAYASKLYAILEEEPKATVKDFVDAIDYTVRKIGIDHVGISSDFNDGGGVKGFN
DVSEIRNVTAELIERGYAEADITKLWGGNFLRVWEQVQAAARPDMKHMNLSNAATRPSGADAHD
>Mature_463_residues
TRPRWKKALFIGLPLALAISAGAGFLAWNYWSPAGYPVKVMQQADDLQERIISFDSHITVPMKFGSEGNEADKDGSGQFD
LVKAARGRLSGAALTVFGWPEIWNGDNAPHRPTPGFVDEARHQQEVRYKIITGMVRDFPNQVGIAYTPDDMRRLHGEGKF
AIFISMLNAYPLGNDLSLLDHWTARGMRMFGFSYVGNNSWADSSRPLPFLNDTPDALGGLSEIGRQAVQRLNDLGVIIDV
SQMSSKALQQVSELSRTPMVASHSTPRALVDIPRNLSDEELQLIKRSGGVVQIVAFPAYLKPLSQKTQDKLNALRKDFDL
PPLPNLAMALMPGDPIITVWPEQRFGAYASKLYAILEEEPKATVKDFVDAIDYTVRKIGIDHVGISSDFNDGGGVKGFND
VSEIRNVTAELIERGYAEADITKLWGGNFLRVWEQVQAAARPDMKHMNLSNAATRPSGADAHD

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=289, Percent_Identity=25.9515570934256, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI193211608, Length=285, Percent_Identity=25.9649122807018, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI193211610, Length=285, Percent_Identity=25.9649122807018, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI189458885, Length=175, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4758190, Length=175, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281362638, Length=181, Percent_Identity=29.2817679558011, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281362636, Length=181, Percent_Identity=29.2817679558011, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI221475880, Length=234, Percent_Identity=24.3589743589744, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161083233, Length=256, Percent_Identity=23.828125, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000180
- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 51223; Mature: 51092

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPRWKKALFIGLPLALAISAGAGFLAWNYWSPAGYPVKVMQQADDLQERIISFDSHIT
CCCCCHHHEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
VPMKFGSEGNEADKDGSGQFDLVKAARGRLSGAALTVFGWPEIWNGDNAPHRPTPGFVDE
EEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCHHCCCCCCCCCCCCCHHHH
ARHQQEVRYKIITGMVRDFPNQVGIAYTPDDMRRLHGEGKFAIFISMLNAYPLGNDLSLL
HHHHHHHHHHHHHHHHHHCCHHCCCEECCHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHH
DHWTARGMRMFGFSYVGNNSWADSSRPLPFLNDTPDALGGLSEIGRQAVQRLNDLGVIID
HHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
VSQMSSKALQQVSELSRTPMVASHSTPRALVDIPRNLSDEELQLIKRSGGVVQIVAFPAY
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHCCCCCCHHHHHHHHHCCCEEEEEECHHH
LKPLSQKTQDKLNALRKDFDLPPLPNLAMALMPGDPIITVWPEQRFGAYASKLYAILEEE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC
PKATVKDFVDAIDYTVRKIGIDHVGISSDFNDGGGVKGFNDVSEIRNVTAELIERGYAEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
DITKLWGGNFLRVWEQVQAAARPDMKHMNLSNAATRPSGADAHD
HHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPRWKKALFIGLPLALAISAGAGFLAWNYWSPAGYPVKVMQQADDLQERIISFDSHIT
CCCCHHHEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
VPMKFGSEGNEADKDGSGQFDLVKAARGRLSGAALTVFGWPEIWNGDNAPHRPTPGFVDE
EEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCHHCCCCCCCCCCCCCHHHH
ARHQQEVRYKIITGMVRDFPNQVGIAYTPDDMRRLHGEGKFAIFISMLNAYPLGNDLSLL
HHHHHHHHHHHHHHHHHHCCHHCCCEECCHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHH
DHWTARGMRMFGFSYVGNNSWADSSRPLPFLNDTPDALGGLSEIGRQAVQRLNDLGVIID
HHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
VSQMSSKALQQVSELSRTPMVASHSTPRALVDIPRNLSDEELQLIKRSGGVVQIVAFPAY
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHCCCCCCHHHHHHHHHCCCEEEEEECHHH
LKPLSQKTQDKLNALRKDFDLPPLPNLAMALMPGDPIITVWPEQRFGAYASKLYAILEEE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC
PKATVKDFVDAIDYTVRKIGIDHVGISSDFNDGGGVKGFNDVSEIRNVTAELIERGYAEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
DITKLWGGNFLRVWEQVQAAARPDMKHMNLSNAATRPSGADAHD
HHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2536663 [H]