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The map label for this gene is zurA [H]

Identifier: 66045190

GI number: 66045190

Start: 2235206

End: 2235970

Strand: Reverse

Name: zurA [H]

Synonym: Psyr_1950

Alternate gene names: 66045190

Gene position: 2235970-2235206 (Counterclockwise)

Preceding gene: 66045191

Following gene: 66045189

Centisome position: 36.69

GC content: 63.92

Gene sequence:

>765_bases
ATGACGGCTGCACAGCACCTCGACATCGTCAGCCAGGGGCCGGGCATCGAATTCAATCAGGTCAGCCTGACCCTCGGGCG
CACCACGATTCTCGATCAGGTTCACTTCAATGTGCGCGCCGGCAGCGTACACGCACTGGTCGGCCCGAACGGCGGTGGCA
AAAGTTCGCTGATCAAGACCCTGCTCGGGCAGACACCGCATCAAGGTCAGTTGAGCCTGCTGTGGCCTGCCGCTCCGGGG
CTGATCGGCTATGTTCCACAGGCGCTGGAGTTCGACCGTGGCCTGCCGATGACCGTGGACGATTTCATGGCGGCCATGTG
TCAGCGACGCCCGGCGTTTCTGGGCTTGTCGAAGCACTACGCGGCAGCGATTGGCGAGGCATTGGAACGGGTCGGCATGC
AGGACAAGCGCAAACGGCGCATGGGCGCGCTTTCCGGTGGCGAACGGCAGCGCGTATTGCTGGCGCAGGGGCTGATTCCT
GCGCCGCAATTGCTGGTGCTGGATGAGCCGATGTCGGCGCTGGATGAGGCGGGTATTCAGGTGTTTGAGCGGTTGTTGGG
TGACTGGCGCCGAAGCGGAGTCACGGTCCTGTGGATCGAGCATGATCTGGATGCCGTCAGGCGTCTGGCCGATCAGGTCA
CAGGGCTCAACCGACGCATCCTGTTCGATGAACCGGCCGCCACCGCGCTGACCCCGGAACGGCTGCTGACCCTGTTTTCC
GCGCACCCGCGCACGATGGATAGCAGCGCCGGGAGGATCGCGTAA

Upstream 100 bases:

>100_bases
TGTCGCACATTTCCTATGGCGAGTACACCGCCGACAAGTACGAAAAGGAAATGGCCGGCAACCTCGACACGGTGGTACGT
GCCATTCAGGAGTCGGGCGC

Downstream 100 bases:

>100_bases
TGGATTACGAAACCTTTCGCCTGTTCATTCAGGGTCTCGCCTCGTCCGGTTACCTGCCCGAGGCGCTGGCCTACGGTTTT
GTGGTCAACGCCCTGCTCGC

Product: ABC transporter

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTAAQHLDIVSQGPGIEFNQVSLTLGRTTILDQVHFNVRAGSVHALVGPNGGGKSSLIKTLLGQTPHQGQLSLLWPAAPG
LIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKHYAAAIGEALERVGMQDKRKRRMGALSGGERQRVLLAQGLIP
APQLLVLDEPMSALDEAGIQVFERLLGDWRRSGVTVLWIEHDLDAVRRLADQVTGLNRRILFDEPAATALTPERLLTLFS
AHPRTMDSSAGRIA

Sequences:

>Translated_254_residues
MTAAQHLDIVSQGPGIEFNQVSLTLGRTTILDQVHFNVRAGSVHALVGPNGGGKSSLIKTLLGQTPHQGQLSLLWPAAPG
LIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKHYAAAIGEALERVGMQDKRKRRMGALSGGERQRVLLAQGLIP
APQLLVLDEPMSALDEAGIQVFERLLGDWRRSGVTVLWIEHDLDAVRRLADQVTGLNRRILFDEPAATALTPERLLTLFS
AHPRTMDSSAGRIA
>Mature_253_residues
TAAQHLDIVSQGPGIEFNQVSLTLGRTTILDQVHFNVRAGSVHALVGPNGGGKSSLIKTLLGQTPHQGQLSLLWPAAPGL
IGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKHYAAAIGEALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPA
PQLLVLDEPMSALDEAGIQVFERLLGDWRRSGVTVLWIEHDLDAVRRLADQVTGLNRRILFDEPAATALTPERLLTLFSA
HPRTMDSSAGRIA

Specific function: Involved in a zinc uptake transport system (Probable) [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1788165, Length=227, Percent_Identity=36.5638766519824, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787164, Length=208, Percent_Identity=33.6538461538462, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786398, Length=236, Percent_Identity=30.0847457627119, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081834, Length=205, Percent_Identity=34.1463414634146, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081791, Length=214, Percent_Identity=31.7757009345794, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789891, Length=241, Percent_Identity=31.1203319502075, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790544, Length=255, Percent_Identity=24.7058823529412, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789873, Length=204, Percent_Identity=31.8627450980392, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787712, Length=210, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786563, Length=191, Percent_Identity=31.9371727748691, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786345, Length=212, Percent_Identity=32.5471698113208, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=218, Percent_Identity=30.2752293577982, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790739, Length=245, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789593, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787089, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788053, Length=200, Percent_Identity=34, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788002, Length=246, Percent_Identity=28.4552845528455, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789672, Length=250, Percent_Identity=27.2, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=210, Percent_Identity=28.0952380952381, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788506, Length=225, Percent_Identity=32.4444444444444, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=28.0172413793103, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786319, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789962, Length=198, Percent_Identity=29.7979797979798, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790190, Length=216, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789864, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994943, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787792, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790467, Length=210, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788897, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788210, Length=213, Percent_Identity=24.8826291079812, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787041, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788450, Length=225, Percent_Identity=27.1111111111111, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786975, Length=204, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI87082267, Length=202, Percent_Identity=27.7227722772277, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789751, Length=166, Percent_Identity=33.1325301204819, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693107, Length=218, Percent_Identity=27.9816513761468, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=243, Percent_Identity=29.2181069958848, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24662800, Length=214, Percent_Identity=28.9719626168224, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85726357, Length=231, Percent_Identity=29.004329004329, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27580; Mature: 27449

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAQHLDIVSQGPGIEFNQVSLTLGRTTILDQVHFNVRAGSVHALVGPNGGGKSSLIKT
CCCHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHH
LLGQTPHQGQLSLLWPAAPGLIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKHY
HHCCCCCCCCEEEECCCCCCHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AAAIGEALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPAPQLLVLDEPMSALDEAGIQ
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHCCCCCCCEEEECCCHHHHHHHHHH
VFERLLGDWRRSGVTVLWIEHDLDAVRRLADQVTGLNRRILFDEPAATALTPERLLTLFS
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHCCHHHHHHHHH
AHPRTMDSSAGRIA
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TAAQHLDIVSQGPGIEFNQVSLTLGRTTILDQVHFNVRAGSVHALVGPNGGGKSSLIKT
CCHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHH
LLGQTPHQGQLSLLWPAAPGLIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKHY
HHCCCCCCCCEEEECCCCCCHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AAAIGEALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPAPQLLVLDEPMSALDEAGIQ
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHCCCCCCCEEEECCCHHHHHHHHHH
VFERLLGDWRRSGVTVLWIEHDLDAVRRLADQVTGLNRRILFDEPAATALTPERLLTLFS
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCHHCCHHHHHHHHH
AHPRTMDSSAGRIA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]