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The map label for this gene is lolC [H]

Identifier: 66045147

GI number: 66045147

Start: 2181325

End: 2182569

Strand: Direct

Name: lolC [H]

Synonym: Psyr_1906

Alternate gene names: 66045147

Gene position: 2181325-2182569 (Clockwise)

Preceding gene: 66045146

Following gene: 161486732

Centisome position: 35.8

GC content: 61.61

Gene sequence:

>1245_bases
ATGTTCAGACCGTTACCCATCTTCATCGGCATGCGCTATACCCGCGCCAAACGCCGCAAAAGCTTCATCTCGTTCATTTC
GATGACCTCGATGATCGGTCTGGCACTCGGTGTCCTGGCGATGATCGTGGTGCTGTCGGTCATGAACGGTTTCCAGCGGG
AAATGAGCTCGCGGATTCTCGGCATGGTGCCGCACGCGGTGATTGCCGGTAGCACTCCGGTCGATGACTGGAAACCGCTG
GCCGACGCGGCGCTGAAAAACCCTGAAGTGACCGCTGCCGTGCCGTTCACCGACATGGAAGGCATGCTCTCCTACAAGGG
CTCGATGCAGCCGATCCAGATCAGCGGCGTAGACCCGGCGCTGGAACATGAGGTGTCGATCGTCACGCAGCACATCACCC
GCGGAAACCTCGAAGACCTCAAGCCGGGCGAGTTCGGCGTAGTGCTCGGCGACATCACCGCGCGCCGCTTTCGCCTGAGC
ATCGGCGACAAGCTGACCCTGATCGTCCCGGAAGTCAGCAGCGCTCCTGGCGGCATCACGCCGCGCATGCAACGCCTGAC
CGTCGTGGGTATCTTCAAGGTCGGTGCCGAACTGGATGGTTCGATGGGCCTGATCAACATCGCCGATGCGGCGCAGATGC
AACGCTGGCAGCCCAATCAGGTTCAGGGCGTGCGGCTGGCGCTCAAGGATCTGTACAAGGCACCCCAGGTGTCCACCGCC
ATTGCCGCCGGTCTGGGTGAGGGCTATCGCGCCGATGACTGGACCCACACCCAGGGCAGCCTGTTCAGCGCCATGAAGAT
GGAAAAGACCATGATCGGTCTGTTGCTGCTGATGATCGTCGCCGTGGCAGCGTTCAACATCATTGCCACGCTGATCATGG
TGGTCAACGACAAGGGCGCAGACATCGCCATCCTGCGCACCATCGGCGCCACGCCGCGGCAGATCATGGCGATCTTCGTG
GTTCAGGGCACCGTCATCGGCATCGTCGGTACCTTGATCGGCGGCATCCTGGGGATTATTGCGGCGCTGAACGTCAGCAG
CCTGGTGGGCTGGGTCGAGCGGGTCAGCGGTCAGCACATCTTCAGTTCCGATGTGTACTTCATCAGCAACCTGCCTTCCG
AACTGCAGGCCGGTGACGTGCTGCTGATCTGCAGTGCCGGGTTTATCCTGAGCTTTCTGGCGACCATCTACCCTGCGTGG
CGCGCCGCGCAGATCCAGCCAGCGCACGCACTGCGTTACGAGTGA

Upstream 100 bases:

>100_bases
AGACGGCCGCCTCGTCGAGGCCTGATCGACCCGGCCCGGCGCAATTCATCGCGTCGGGTTCCAGTTTTTATACGGTGTAT
TTTTCCACGGTGCTTCGCGA

Downstream 100 bases:

>100_bases
CGGGGCCTGAGTCACCTTCGTCGAGGCCGCAGGGCGGCCTGCGAGGGTGGCGGGGCAGAGCGGATTTTCGCTGAAAGCCC
CAGGCAAACGCTATAAACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MFRPLPIFIGMRYTRAKRRKSFISFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRILGMVPHAVIAGSTPVDDWKPL
ADAALKNPEVTAAVPFTDMEGMLSYKGSMQPIQISGVDPALEHEVSIVTQHITRGNLEDLKPGEFGVVLGDITARRFRLS
IGDKLTLIVPEVSSAPGGITPRMQRLTVVGIFKVGAELDGSMGLINIADAAQMQRWQPNQVQGVRLALKDLYKAPQVSTA
IAAGLGEGYRADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGADIAILRTIGATPRQIMAIFV
VQGTVIGIVGTLIGGILGIIAALNVSSLVGWVERVSGQHIFSSDVYFISNLPSELQAGDVLLICSAGFILSFLATIYPAW
RAAQIQPAHALRYE

Sequences:

>Translated_414_residues
MFRPLPIFIGMRYTRAKRRKSFISFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRILGMVPHAVIAGSTPVDDWKPL
ADAALKNPEVTAAVPFTDMEGMLSYKGSMQPIQISGVDPALEHEVSIVTQHITRGNLEDLKPGEFGVVLGDITARRFRLS
IGDKLTLIVPEVSSAPGGITPRMQRLTVVGIFKVGAELDGSMGLINIADAAQMQRWQPNQVQGVRLALKDLYKAPQVSTA
IAAGLGEGYRADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGADIAILRTIGATPRQIMAIFV
VQGTVIGIVGTLIGGILGIIAALNVSSLVGWVERVSGQHIFSSDVYFISNLPSELQAGDVLLICSAGFILSFLATIYPAW
RAAQIQPAHALRYE
>Mature_414_residues
MFRPLPIFIGMRYTRAKRRKSFISFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRILGMVPHAVIAGSTPVDDWKPL
ADAALKNPEVTAAVPFTDMEGMLSYKGSMQPIQISGVDPALEHEVSIVTQHITRGNLEDLKPGEFGVVLGDITARRFRLS
IGDKLTLIVPEVSSAPGGITPRMQRLTVVGIFKVGAELDGSMGLINIADAAQMQRWQPNQVQGVRLALKDLYKAPQVSTA
IAAGLGEGYRADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGADIAILRTIGATPRQIMAIFV
VQGTVIGIVGTLIGGILGIIAALNVSSLVGWVERVSGQHIFSSDVYFISNLPSELQAGDVLLICSAGFILSFLATIYPAW
RAAQIQPAHALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=412, Percent_Identity=35.4368932038835, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1787360, Length=415, Percent_Identity=36.8674698795181, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44561; Mature: 44561

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPLPIFIGMRYTRAKRRKSFISFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRIL
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVPHAVIAGSTPVDDWKPLADAALKNPEVTAAVPFTDMEGMLSYKGSMQPIQISGVDPA
HHCCHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCEEEEECCCHH
LEHEVSIVTQHITRGNLEDLKPGEFGVVLGDITARRFRLSIGDKLTLIVPEVSSAPGGIT
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCCCC
PRMQRLTVVGIFKVGAELDGSMGLINIADAAQMQRWQPNQVQGVRLALKDLYKAPQVSTA
CHHHHEEEEEEEEECCCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
IAAGLGEGYRADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DIAILRTIGATPRQIMAIFVVQGTVIGIVGTLIGGILGIIAALNVSSLVGWVERVSGQHI
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FSSDVYFISNLPSELQAGDVLLICSAGFILSFLATIYPAWRAAQIQPAHALRYE
ECCCCCEECCCCCHHCCCCEEEEECHHHHHHHHHHHCCCHHCCCCCCCHHCCCC
>Mature Secondary Structure
MFRPLPIFIGMRYTRAKRRKSFISFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRIL
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVPHAVIAGSTPVDDWKPLADAALKNPEVTAAVPFTDMEGMLSYKGSMQPIQISGVDPA
HHCCHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCEEEEECCCHH
LEHEVSIVTQHITRGNLEDLKPGEFGVVLGDITARRFRLSIGDKLTLIVPEVSSAPGGIT
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCCCC
PRMQRLTVVGIFKVGAELDGSMGLINIADAAQMQRWQPNQVQGVRLALKDLYKAPQVSTA
CHHHHEEEEEEEEECCCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
IAAGLGEGYRADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DIAILRTIGATPRQIMAIFVVQGTVIGIVGTLIGGILGIIAALNVSSLVGWVERVSGQHI
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FSSDVYFISNLPSELQAGDVLLICSAGFILSFLATIYPAWRAAQIQPAHALRYE
ECCCCCEECCCCCHHCCCCEEEEECHHHHHHHHHHHCCCHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]