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The map label for this gene is lolC [H]

Identifier: 66045145

GI number: 66045145

Start: 2179308

End: 2180558

Strand: Direct

Name: lolC [H]

Synonym: Psyr_1904

Alternate gene names: 66045145

Gene position: 2179308-2180558 (Clockwise)

Preceding gene: 66045142

Following gene: 66045146

Centisome position: 35.76

GC content: 60.35

Gene sequence:

>1251_bases
ATGTTCAGACCTCTTTTTGTATTTATCGGCACGCGCTACACCCGTGCGAAGCGACGCAATCATTTTGTTTCCTTCATCTC
CCTGACCTCCATGATCGGCCTCGCCCTGGGCGTTGTGGTCATGATAGTCGTGTTATCGGTGATGAACGGTTTCGATCACG
AAATGCGTACCCGCGTGCTCGGCATGGTGCCGCACGCGACCATCGAATCGGCTGACCCGATCACCGACTGGCGCGGTCTG
GCCGCGAAGGTTCAGGAAAACCCGCAGGTGCTGGCCGTTGCGCCGTTCACCCAGATGCAGGGCTTGCTGACCCACGACGG
CAAGGTCCAGAAAGTGCTGCTCAACGGTATCGACCCGCTTGAAGAGCGCAAGGTCTCGATCATTGACCACTTCATCAAGC
AGGGCCAGCTCGACAGTCTGTCGCCCGGCAGCTTCGGCATCATGATCGGCGACAAGGCCGCGGCCAAGCTGGGCGTCGGC
ATCGGCGACAAGCTGACCTTCGTTGCGCCTGAAGTGACGGTGACGCCAGCCGGGATGTTCCCGCGCATGAAGCGCTTCGA
GGTGACCGGCATCTTTCACGTCGGCGCCGGCGAAATCGACGGCTTCCTGGGGCTGACCAACCTTGATGACCTGGGCCGTC
TGCACCGCTGGAAGCCCAATCAGGTGCAGGGCCTGCGTCTCAAGTTCGACGACCTGTTCGCCGCGCCACGCACTTCGTGG
GAAATCGCGCAGAAGCTGGGCGAAAACAACTTCTACTCGCGTGACTGGACGCGCACCCACGGCAACCTGTATCAGGCCAT
CCGCATGGAAAAAGCCATGATCGGTCTGTTGCTGCTGCTGATCGTGGCGGTGGCGGCCTTCAACATCATTTCCACGCTGG
TGATGGTGGTCAATGACAAGAAGGGCGACATCGCGATTCTGCGTACCCTGGGTGCTACGCCGCGACAGATCATGGCGATA
TTCATGGTCCAGGGCACGGTGATCGGCGTGGTTGGCACGCTGATCGGCGCGGCACTGGGGATTCTGGCGGCGCTCAATGT
CAGTGCTGCCATTGCTGCACTCGAAGGGCTGATCGGCCACAAGTTTCTCAACGCCGACGTCTACTTCATTGATTACCTGC
CTTCGCAACTGATGGCCCAGGACGTGTTCCAGGTCTGTGGTGCAGCGTTGGTCCTGAGTTTCCTCGCCACCCTGTATCCC
GCCTGGCGTGCTGCGCGCACCCAGCCGGCGGAGGCGTTACGTTATGAGTGA

Upstream 100 bases:

>100_bases
CGAACCCAAGCTAGCGGCGGTGGTCAGAGAGTTTCGAGTGTAAAGCTGCACGTCAAGGCCCGCCACACGGACGTCCTCAT
TCCTGCGAACAAATTCCTAC

Downstream 100 bases:

>100_bases
GTCGGGCATGTCTGATAAAGCAGTATTGAGTTGCCGCAACCTGGGTAAATCCTACGAGGAAGGCCCGGAGTCGGTGGTGG
TGTTGTCCGGCCTGCAGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFRPLFVFIGTRYTRAKRRNHFVSFISLTSMIGLALGVVVMIVVLSVMNGFDHEMRTRVLGMVPHATIESADPITDWRGL
AAKVQENPQVLAVAPFTQMQGLLTHDGKVQKVLLNGIDPLEERKVSIIDHFIKQGQLDSLSPGSFGIMIGDKAAAKLGVG
IGDKLTFVAPEVTVTPAGMFPRMKRFEVTGIFHVGAGEIDGFLGLTNLDDLGRLHRWKPNQVQGLRLKFDDLFAAPRTSW
EIAQKLGENNFYSRDWTRTHGNLYQAIRMEKAMIGLLLLLIVAVAAFNIISTLVMVVNDKKGDIAILRTLGATPRQIMAI
FMVQGTVIGVVGTLIGAALGILAALNVSAAIAALEGLIGHKFLNADVYFIDYLPSQLMAQDVFQVCGAALVLSFLATLYP
AWRAARTQPAEALRYE

Sequences:

>Translated_416_residues
MFRPLFVFIGTRYTRAKRRNHFVSFISLTSMIGLALGVVVMIVVLSVMNGFDHEMRTRVLGMVPHATIESADPITDWRGL
AAKVQENPQVLAVAPFTQMQGLLTHDGKVQKVLLNGIDPLEERKVSIIDHFIKQGQLDSLSPGSFGIMIGDKAAAKLGVG
IGDKLTFVAPEVTVTPAGMFPRMKRFEVTGIFHVGAGEIDGFLGLTNLDDLGRLHRWKPNQVQGLRLKFDDLFAAPRTSW
EIAQKLGENNFYSRDWTRTHGNLYQAIRMEKAMIGLLLLLIVAVAAFNIISTLVMVVNDKKGDIAILRTLGATPRQIMAI
FMVQGTVIGVVGTLIGAALGILAALNVSAAIAALEGLIGHKFLNADVYFIDYLPSQLMAQDVFQVCGAALVLSFLATLYP
AWRAARTQPAEALRYE
>Mature_416_residues
MFRPLFVFIGTRYTRAKRRNHFVSFISLTSMIGLALGVVVMIVVLSVMNGFDHEMRTRVLGMVPHATIESADPITDWRGL
AAKVQENPQVLAVAPFTQMQGLLTHDGKVQKVLLNGIDPLEERKVSIIDHFIKQGQLDSLSPGSFGIMIGDKAAAKLGVG
IGDKLTFVAPEVTVTPAGMFPRMKRFEVTGIFHVGAGEIDGFLGLTNLDDLGRLHRWKPNQVQGLRLKFDDLFAAPRTSW
EIAQKLGENNFYSRDWTRTHGNLYQAIRMEKAMIGLLLLLIVAVAAFNIISTLVMVVNDKKGDIAILRTLGATPRQIMAI
FMVQGTVIGVVGTLIGAALGILAALNVSAAIAALEGLIGHKFLNADVYFIDYLPSQLMAQDVFQVCGAALVLSFLATLYP
AWRAARTQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=38.8888888888889, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=38.6091127098321, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45529; Mature: 45529

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPLFVFIGTRYTRAKRRNHFVSFISLTSMIGLALGVVVMIVVLSVMNGFDHEMRTRVL
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPHATIESADPITDWRGLAAKVQENPQVLAVAPFTQMQGLLTHDGKVQKVLLNGIDPL
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCHHHHHHHCCCCCH
EERKVSIIDHFIKQGQLDSLSPGSFGIMIGDKAAAKLGVGIGDKLTFVAPEVTVTPAGMF
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCCEEEECCCEEECCCCCC
PRMKRFEVTGIFHVGAGEIDGFLGLTNLDDLGRLHRWKPNQVQGLRLKFDDLFAAPRTSW
CCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCHH
EIAQKLGENNFYSRDWTRTHGNLYQAIRMEKAMIGLLLLLIVAVAAFNIISTLVMVVNDK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGDIAILRTLGATPRQIMAIFMVQGTVIGVVGTLIGAALGILAALNVSAAIAALEGLIGH
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFLNADVYFIDYLPSQLMAQDVFQVCGAALVLSFLATLYPAWRAARTQPAEALRYE
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MFRPLFVFIGTRYTRAKRRNHFVSFISLTSMIGLALGVVVMIVVLSVMNGFDHEMRTRVL
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPHATIESADPITDWRGLAAKVQENPQVLAVAPFTQMQGLLTHDGKVQKVLLNGIDPL
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCHHHHHHHCCCCCH
EERKVSIIDHFIKQGQLDSLSPGSFGIMIGDKAAAKLGVGIGDKLTFVAPEVTVTPAGMF
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCCEEEECCCEEECCCCCC
PRMKRFEVTGIFHVGAGEIDGFLGLTNLDDLGRLHRWKPNQVQGLRLKFDDLFAAPRTSW
CCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCHH
EIAQKLGENNFYSRDWTRTHGNLYQAIRMEKAMIGLLLLLIVAVAAFNIISTLVMVVNDK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGDIAILRTLGATPRQIMAIFMVQGTVIGVVGTLIGAALGILAALNVSAAIAALEGLIGH
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFLNADVYFIDYLPSQLMAQDVFQVCGAALVLSFLATLYPAWRAARTQPAEALRYE
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]