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The map label for this gene is gufA [H]

Identifier: 66045106

GI number: 66045106

Start: 2138075

End: 2139001

Strand: Reverse

Name: gufA [H]

Synonym: Psyr_1862

Alternate gene names: 66045106

Gene position: 2139001-2138075 (Counterclockwise)

Preceding gene: 66045116

Following gene: 66045103

Centisome position: 35.1

GC content: 64.4

Gene sequence:

>927_bases
ATGCCTACGCCCGCATCATCCCGAACGCCCTGGGCGGCCTGGTTAAACCAGCTTCAGGGCAGCCCGCTGGTAAGCCTGGG
CTTCGCCCTCGCCCTGCTGATCGTCGTCGCCCTCGGTGGCATCAGCCTTTACAACGCCTTCTATGGCACCAGTCAGGTCA
ACTTCAATCACGCCCTGCTGGGCGGTATCGCGGGTTTTCTGGCGACGGCGCTAGGCGCAGTGATGGCGGTTGCCCTGCGC
AACGTCTCGCAACGCGCTCAGGACATCATGCTCGGGTTCGCTGCGGGGATGATGCTGGCGGCCAGTTCGTTCTCGCTGAT
TCTTCCAGGCCTGGAAGCCGCCCGGGACATTACCGACAGCGGGCCGTGGGCAGCTGCGACGGTTGTCGCCGGCCTGGGGC
TGGGGGTGCTGCTGATGCTGGGGCTGGACCGGTTCACCCCGCACGAACATGAAAGCGTAGGCCGCCAGGGGCCTCATTCG
GATCGAATCAGTCGGGTCTGGCTGTTCGTGCTGGCGATCACCCTGCATAACCTGCCCGAGGGCATGGCGATTGGCGTCAG
TTTCGCCAGCGGCGACATGAACGTCGGCCTGCCATTGACCACGGCCATCGCCATTCAGGACATTCCCGAAGGTCTGGCCA
TTGCGCTGGCCCTGCGTGCGACCGGCCTGTCGGCCTTCAAGGCGATGCTGGTGGCCATCGGTTCCGGCCTCATGGAGCCG
CTGGGCTCACTGGTGGGCCTGGGCATCTCCAGCGGCTTTGCCATCGCCTACCCCTTGAGCATGGGGCTGGCGGCAGGCGC
GATGATCTTCGTGGTCTCTCATGAAGTCATCCCGGAAACCCACCGCAATGGCCATCAGACCTCGGCAACCCTGGGCCTGA
TGGGCGGCTTTGCGGTGATGATGTTTCTCGATACGGCGCTGGGTTAA

Upstream 100 bases:

>100_bases
GTTCCGTTGAACCAACCTTATATTCTCGGGCTCCCAGACGGGGTCGACTTTATATTTCAGTCACCATTGCTTCTCCCCCT
TTACAAAGGTAGCCCTATCA

Downstream 100 bases:

>100_bases
CCGCGCAAGGCTTGCAATGCAGGTGCGGCATGGATGCCGGCCGTTGCTGCCAGCTCGACTACGCGTGCTTCGTCACGGCC
ATACACCAGCACCGCTTGCA

Product: Zinc transporter ZIP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPTPASSRTPWAAWLNQLQGSPLVSLGFALALLIVVALGGISLYNAFYGTSQVNFNHALLGGIAGFLATALGAVMAVALR
NVSQRAQDIMLGFAAGMMLAASSFSLILPGLEAARDITDSGPWAAATVVAGLGLGVLLMLGLDRFTPHEHESVGRQGPHS
DRISRVWLFVLAITLHNLPEGMAIGVSFASGDMNVGLPLTTAIAIQDIPEGLAIALALRATGLSAFKAMLVAIGSGLMEP
LGSLVGLGISSGFAIAYPLSMGLAAGAMIFVVSHEVIPETHRNGHQTSATLGLMGGFAVMMFLDTALG

Sequences:

>Translated_308_residues
MPTPASSRTPWAAWLNQLQGSPLVSLGFALALLIVVALGGISLYNAFYGTSQVNFNHALLGGIAGFLATALGAVMAVALR
NVSQRAQDIMLGFAAGMMLAASSFSLILPGLEAARDITDSGPWAAATVVAGLGLGVLLMLGLDRFTPHEHESVGRQGPHS
DRISRVWLFVLAITLHNLPEGMAIGVSFASGDMNVGLPLTTAIAIQDIPEGLAIALALRATGLSAFKAMLVAIGSGLMEP
LGSLVGLGISSGFAIAYPLSMGLAAGAMIFVVSHEVIPETHRNGHQTSATLGLMGGFAVMMFLDTALG
>Mature_307_residues
PTPASSRTPWAAWLNQLQGSPLVSLGFALALLIVVALGGISLYNAFYGTSQVNFNHALLGGIAGFLATALGAVMAVALRN
VSQRAQDIMLGFAAGMMLAASSFSLILPGLEAARDITDSGPWAAATVVAGLGLGVLLMLGLDRFTPHEHESVGRQGPHSD
RISRVWLFVLAITLHNLPEGMAIGVSFASGDMNVGLPLTTAIAIQDIPEGLAIALALRATGLSAFKAMLVAIGSGLMEPL
GSLVGLGISSGFAIAYPLSMGLAAGAMIFVVSHEVIPETHRNGHQTSATLGLMGGFAVMMFLDTALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=162, Percent_Identity=38.8888888888889, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI229577422, Length=162, Percent_Identity=38.8888888888889, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1789419, Length=244, Percent_Identity=34.0163934426229, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507805, Length=314, Percent_Identity=32.1656050955414, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652846, Length=169, Percent_Identity=39.6449704142012, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 31617; Mature: 31485

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPASSRTPWAAWLNQLQGSPLVSLGFALALLIVVALGGISLYNAFYGTSQVNFNHALL
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GGIAGFLATALGAVMAVALRNVSQRAQDIMLGFAAGMMLAASSFSLILPGLEAARDITDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCC
GPWAAATVVAGLGLGVLLMLGLDRFTPHEHESVGRQGPHSDRISRVWLFVLAITLHNLPE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
GMAIGVSFASGDMNVGLPLTTAIAIQDIPEGLAIALALRATGLSAFKAMLVAIGSGLMEP
CEEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLVGLGISSGFAIAYPLSMGLAAGAMIFVVSHEVIPETHRNGHQTSATLGLMGGFAVM
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
MFLDTALG
HHHHHHCC
>Mature Secondary Structure 
PTPASSRTPWAAWLNQLQGSPLVSLGFALALLIVVALGGISLYNAFYGTSQVNFNHALL
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GGIAGFLATALGAVMAVALRNVSQRAQDIMLGFAAGMMLAASSFSLILPGLEAARDITDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCC
GPWAAATVVAGLGLGVLLMLGLDRFTPHEHESVGRQGPHSDRISRVWLFVLAITLHNLPE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
GMAIGVSFASGDMNVGLPLTTAIAIQDIPEGLAIALALRATGLSAFKAMLVAIGSGLMEP
CEEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLVGLGISSGFAIAYPLSMGLAAGAMIFVVSHEVIPETHRNGHQTSATLGLMGGFAVM
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
MFLDTALG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]