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The map label for this gene is pyrF [H]

Identifier: 66045080

GI number: 66045080

Start: 2116402

End: 2117136

Strand: Direct

Name: pyrF [H]

Synonym: Psyr_1836

Alternate gene names: 66045080

Gene position: 2116402-2117136 (Clockwise)

Preceding gene: 66045077

Following gene: 66045082

Centisome position: 34.73

GC content: 64.76

Gene sequence:

>735_bases
ATGCGCGCCGATTTCGACTTACCTGAGACCACGCTCATGTCCGCCTGCCAGACTCCTGTCATCGTCGCCCTGGATTTTCC
GACCCGCGAAGCCGCCTTGCGCCTGGCTGATCAGCTCGACCCCAAACTGTGCAGGGTCAAGGTCGGCAAGGAACTGTTCA
CCAGTTGCGCGGCCGACATCGTCGAGACCCTGCGCCACAGGGGCTTCGAAGTGTTTCTGGATCTCAAATTCCACGACATC
CCCAACACCACGGCGATGGCGGTCAAGGCGGCGGCCGAGATGGGCGTGTGGATGGTCAATGTGCACTGCTCGGGCGGCTT
GCGCATGATGGCGGCCTGTCGGGAAGTGCTTGAGCAGCGCACCGGTCCACAGCCGTTGCTGATCGGCGTGACCGTTCTGA
CCAGCATGGAACGTGAAGACCTGGCCGGTATCGGCCTGGACATCGACCCGCAGGTACAGGTGCTGCGCCTTGCGGCTCTG
GCCGGGAAGGCCGGAATGGATGGTCTGGTCTGCTCGGCACTGGAAGCGCAGGCCCTGAAAGCCGCTCACCCGTCGTTGCA
ACTGGTGACGCCCGGCATCCGTCCGGCGGGCAGTGCGCAGGACGATCAGCGCCGTATCCTGACCCCTCGTCAGGCACTGG
ATGCAGGCTCTGACTACCTCGTCATCGGCCGCCCGATCAGCCAGGCGGCTGATCCGGCGAAGGCCCTGGCGGCGGTGGTT
GCCGAGCTGGCTTGA

Upstream 100 bases:

>100_bases
CGGCGATGACCGCCAGGGGTGCATGGAATTCAGAAGTCTCAGGACGCTGTTCGGGCAAATGCCGATCGATGGGTCCCGCC
TGTGCGCCGGTTCGGCTACA

Downstream 100 bases:

>100_bases
GTAGATGGATGCGTAACATCACGGCTCTACCCACAGAGTGGCGAAGAGCTGTGACGCTGCGAAAAGCCCGCGGGTTTATT
CCACTTTCAGGATCAGCTTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRADFDLPETTLMSACQTPVIVALDFPTREAALRLADQLDPKLCRVKVGKELFTSCAADIVETLRHRGFEVFLDLKFHDI
PNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQRTGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAAL
AGKAGMDGLVCSALEAQALKAAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVV
AELA

Sequences:

>Translated_244_residues
MRADFDLPETTLMSACQTPVIVALDFPTREAALRLADQLDPKLCRVKVGKELFTSCAADIVETLRHRGFEVFLDLKFHDI
PNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQRTGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAAL
AGKAGMDGLVCSALEAQALKAAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVV
AELA
>Mature_244_residues
MRADFDLPETTLMSACQTPVIVALDFPTREAALRLADQLDPKLCRVKVGKELFTSCAADIVETLRHRGFEVFLDLKFHDI
PNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQRTGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAAL
AGKAGMDGLVCSALEAQALKAAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVV
AELA

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=228, Percent_Identity=57.4561403508772, Blast_Score=250, Evalue=5e-68,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26018; Mature: 26018

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADFDLPETTLMSACQTPVIVALDFPTREAALRLADQLDPKLCRVKVGKELFTSCAADI
CCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VETLRHRGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQR
HHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHC
TGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAALAGKAGMDGLVCSALEAQALK
CCCCCEEEHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVV
HCCCCCEEECCCCCCCCCCCCCHHHHCCCHHHHCCCCCEEEEECCHHHHCCHHHHHHHHH
AELA
HHCC
>Mature Secondary Structure
MRADFDLPETTLMSACQTPVIVALDFPTREAALRLADQLDPKLCRVKVGKELFTSCAADI
CCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VETLRHRGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQR
HHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHC
TGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAALAGKAGMDGLVCSALEAQALK
CCCCCEEEHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVV
HCCCCCEEECCCCCCCCCCCCCHHHHCCCHHHHCCCCCEEEEECCHHHHCCHHHHHHHHH
AELA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA