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The map label for this gene is clpX [H]

Identifier: 66044993

GI number: 66044993

Start: 1985531

End: 1986814

Strand: Direct

Name: clpX [H]

Synonym: Psyr_1748

Alternate gene names: 66044993

Gene position: 1985531-1986814 (Clockwise)

Preceding gene: 66044992

Following gene: 66044994

Centisome position: 32.58

GC content: 57.55

Gene sequence:

>1284_bases
ATGACTGACACCCGCAACGGCGAGGACAACGGCAAATTGCTCTATTGCTCCTTCTGTGGCAAAAGCCAGCATGAAGTGCG
CAAATTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGCGTCGACCTGTGCAATGACATCATCCGTGAGGAGGTGC
AGGAAGCCCAGGCCGAAAGCAGCGCGCATAAATTGCCTTCGCCCAAAGAAATCAGCGGCATCCTTGACCAGTACGTAATC
GGTCAGGAACGTGCCAAGAAGGTTCTCGCAGTAGCGGTGTACAACCACTACAAGCGTCTGAACCAGCGTGACAAGAAGAA
CGACGATGTGGAGTTGGGCAAGAGCAACATCCTGCTGATCGGCCCTACGGGCTCCGGCAAGACGCTGCTGGCCGAAACAC
TGGCCCGCCTGCTCAACGTACCGTTCACCATCGCTGACGCCACCACCCTGACCGAAGCCGGTTATGTGGGTGAGGACGTC
GAAAACATTATCCAGAAGCTGTTGCAGAAATGTGATTACGATGTAGAGAAGGCCCAGATGGGTATTGTCTACATCGACGA
AATCGACAAGATCTCGCGCAAATCCGACAACCCTTCGATCACTCGTGACGTGTCCGGTGAAGGCGTGCAGCAAGCCTTGC
TGAAACTGATCGAGGGCACCGTGGCTTCCGTTCCGCCGCAAGGTGGTCGCAAGCACCCGCAGCAGGAATTCCTGCAGGTG
GACACGCGTAATATCCTCTTTATCTGCGGTGGCGCCTTCTCGGGCCTGGAAAAGGTCATTCAGAACCGTTCCACCCGTGG
CGGCATCGGCTTCAACGCCGAGGTTCGCAGCAAGGAGGAGGGCAAGAAGGTTGGCGAGTCGCTGCGTGAAGTCGAGCCTG
ACGATCTGGTCAAGTTCGGTCTGATCCCCGAGTTCGTGGGCCGTCTGCCGGTGCTGGCAACGCTGGACGAGCTGGATGAG
GCTGCTTTGATACAGATCCTCACCGAGCCGAAGAACGCACTGACCAAGCAGTATGCCAAGCTGTTCGAGATGGAAGGTGT
GGACCTCGAGTTCCGGACCGATGCGCTGAAATCGGTCGCCCGTCGCGCGCTGGAGCGCAAGACCGGTGCCCGTGGCCTGC
GTTCGATTCTGGAAGGCGTGCTGCTCGACACCATGTATGAAATCCCGTCGCAGAGCGATGTGAGCAAGGTGGTGATCGAC
GAAAGCGTCATCGATGGCACGTCCAAGCCGCTGTTGATATACGAAAACAGCGAGCCGCCTGCCAAGGTTGCTCCCGACGC
ATAA

Upstream 100 bases:

>100_bases
CAAAATGTAGGGGGTCGGCACAACCGACCGCCTGCGGACTTGAAAAAGCCCGCAATAGCCTTCATCTTGTGTTGCAAGCC
TACCGGATTGGATCGATCGA

Downstream 100 bases:

>100_bases
ACGCATGTTCATAGGCGTGTGAAGTAATACTGAAGGGGGCCTTTTTGGTCCCCTTTTGCATTTTTAAGCCGTTCATTCGT
TTGGTATGAAGAAACTGATC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDE
AALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVARRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVID
ESVIDGTSKPLLIYENSEPPAKVAPDA

Sequences:

>Translated_427_residues
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDE
AALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVARRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVID
ESVIDGTSKPLLIYENSEPPAKVAPDA
>Mature_426_residues
TDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVIG
QERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDEA
ALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVARRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVIDE
SVIDGTSKPLLIYENSEPPAKVAPDA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=52.5525525525526, Blast_Score=324, Evalue=1e-88,
Organism=Escherichia coli, GI1786642, Length=419, Percent_Identity=77.8042959427208, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=44.5544554455446, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=314, Percent_Identity=47.4522292993631, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=47.1153846153846, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=409, Percent_Identity=39.6088019559902, Blast_Score=260, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=42.914979757085, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=40.5092592592593, Blast_Score=282, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=48.4567901234568, Blast_Score=301, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=48.4567901234568, Blast_Score=301, Evalue=8e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46957; Mature: 46826

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAES
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLI
HHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQM
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFG
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
LIPEFVGRLPVLATLDELDEAALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
RRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVIDESVIDGTSKPLLIYENSEPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
AKVAPDA
CCCCCCC
>Mature Secondary Structure 
TDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAES
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLI
HHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQM
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFG
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
LIPEFVGRLPVLATLDELDEAALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
RRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVIDESVIDGTSKPLLIYENSEPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
AKVAPDA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]