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The map label for this gene is prpE [H]

Identifier: 66044931

GI number: 66044931

Start: 1894769

End: 1895734

Strand: Direct

Name: prpE [H]

Synonym: Psyr_1686

Alternate gene names: 66044931

Gene position: 1894769-1895734 (Clockwise)

Preceding gene: 66044930

Following gene: 66044932

Centisome position: 31.09

GC content: 61.8

Gene sequence:

>966_bases
ATGCTCGATCCGGCGCGTGGCTATGATCTGATCGGTGACGTGCACGGGTGTGCCCATACCCTCGAGCACTTGCTGGAGCT
TCTCGGTTACCGTCTGCAGGCTGGCGTGTGGCGCCATCCCGAGCGCATCGTCATTTTCCTCGGCGACATCATCGACCGCG
GCCCGCGTATCCGCGAATCGCTGCACATCGTGCGCGACATGGTCCAGGCCGGTCAGGCGTTGTGCATCATGGGCAACCAT
GAGTTCAACGCGCTGGGCTGGGTGACACCGGCCCTGTCCGAAAGCGGTCATCAGTTCGTGCGCGAGCACACCCCGCGTCA
TGCGCGGCTGATCGGCGAGACCCTGGCGCAGTTCGAGCAATATCCGGATGAGTGGAGCGAGTTCGTCAACTGGTTCTACG
AGTTACCGCTGTACCTCGATGCCGGTCGCTTCAGGGTGGTGCACGCCTGCTGGGATGCGACCCTGATCGATCCGCTGCGT
GGCCTGCATGGTACGGGGTGTATCGATAAGCATTTCGTCCAGGCATCGGCAGTGCCCGGCAGCTTCGCCAGCAATGTCTT
CAATCGTCTGCTGCGTGGCACCGACATGCGCCTGCCGCACGGCCTGACCCTGACTGGCGGTGATGGCCTGACCCGCGAAT
TCTTCCGCACCAAGTTCTGGGAGGATGATCCGCAGACTTACGGCGACGTGGTCTTTCAGCCGGACGCCTTGCCCGAAGGG
GTTGCCAAGACGCCATTGACCACGTCGGAAAAGAACGCCTTGCTGCGGTATGGCATCAATGAGCCGCTGCTGTTTGTCGG
TCATTACTGGCGCAGCGGCATCCCTGCGCCTATCCGGCCGAACCTGGCCTGTCTGGATTACAGCGCCGTGCTCTACGGCA
AACTGGTCGCCTATCGGCTTGACCAGGAAACACAGATCGATCCGGACAAATTCGTCTGGGTCGACGTGCAGCGTCCCGAG
GTTTGA

Upstream 100 bases:

>100_bases
CGCAGAAACTGCGTCTGATCCATCCGTTGGATCACAACTATTACGAGGTCTGCCGCACCAAGCTCGGCTGGGGCAGCAAG
CTCGGCGGCGGGGGCGATTA

Downstream 100 bases:

>100_bases
TAATGAGTCCTGTAGCTGTCCTGCGTTTGCCGCTGACCACCGACCTGAGCGGTTTTGTCAGGCTGTTGCTGCGCTTGCAG
ATTCCTCACCGGGTCAGTGA

Product: metallophosphoesterase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLDPARGYDLIGDVHGCAHTLEHLLELLGYRLQAGVWRHPERIVIFLGDIIDRGPRIRESLHIVRDMVQAGQALCIMGNH
EFNALGWVTPALSESGHQFVREHTPRHARLIGETLAQFEQYPDEWSEFVNWFYELPLYLDAGRFRVVHACWDATLIDPLR
GLHGTGCIDKHFVQASAVPGSFASNVFNRLLRGTDMRLPHGLTLTGGDGLTREFFRTKFWEDDPQTYGDVVFQPDALPEG
VAKTPLTTSEKNALLRYGINEPLLFVGHYWRSGIPAPIRPNLACLDYSAVLYGKLVAYRLDQETQIDPDKFVWVDVQRPE
V

Sequences:

>Translated_321_residues
MLDPARGYDLIGDVHGCAHTLEHLLELLGYRLQAGVWRHPERIVIFLGDIIDRGPRIRESLHIVRDMVQAGQALCIMGNH
EFNALGWVTPALSESGHQFVREHTPRHARLIGETLAQFEQYPDEWSEFVNWFYELPLYLDAGRFRVVHACWDATLIDPLR
GLHGTGCIDKHFVQASAVPGSFASNVFNRLLRGTDMRLPHGLTLTGGDGLTREFFRTKFWEDDPQTYGDVVFQPDALPEG
VAKTPLTTSEKNALLRYGINEPLLFVGHYWRSGIPAPIRPNLACLDYSAVLYGKLVAYRLDQETQIDPDKFVWVDVQRPE
V
>Mature_321_residues
MLDPARGYDLIGDVHGCAHTLEHLLELLGYRLQAGVWRHPERIVIFLGDIIDRGPRIRESLHIVRDMVQAGQALCIMGNH
EFNALGWVTPALSESGHQFVREHTPRHARLIGETLAQFEQYPDEWSEFVNWFYELPLYLDAGRFRVVHACWDATLIDPLR
GLHGTGCIDKHFVQASAVPGSFASNVFNRLLRGTDMRLPHGLTLTGGDGLTREFFRTKFWEDDPQTYGDVVFQPDALPEG
VAKTPLTTSEKNALLRYGINEPLLFVGHYWRSGIPAPIRPNLACLDYSAVLYGKLVAYRLDQETQIDPDKFVWVDVQRPE
V

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 36441; Mature: 36441

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPARGYDLIGDVHGCAHTLEHLLELLGYRLQAGVWRHPERIVIFLGDIIDRGPRIRES
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCCHHHHHH
LHIVRDMVQAGQALCIMGNHEFNALGWVTPALSESGHQFVREHTPRHARLIGETLAQFEQ
HHHHHHHHHCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDEWSEFVNWFYELPLYLDAGRFRVVHACWDATLIDPLRGLHGTGCIDKHFVQASAVPG
CCHHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
SFASNVFNRLLRGTDMRLPHGLTLTGGDGLTREFFRTKFWEDDPQTYGDVVFQPDALPEG
HHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC
VAKTPLTTSEKNALLRYGINEPLLFVGHYWRSGIPAPIRPNLACLDYSAVLYGKLVAYRL
CCCCCCCCCCCCHHEEECCCCCEEEEEHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
DQETQIDPDKFVWVDVQRPEV
CCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MLDPARGYDLIGDVHGCAHTLEHLLELLGYRLQAGVWRHPERIVIFLGDIIDRGPRIRES
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCCHHHHHH
LHIVRDMVQAGQALCIMGNHEFNALGWVTPALSESGHQFVREHTPRHARLIGETLAQFEQ
HHHHHHHHHCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDEWSEFVNWFYELPLYLDAGRFRVVHACWDATLIDPLRGLHGTGCIDKHFVQASAVPG
CCHHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
SFASNVFNRLLRGTDMRLPHGLTLTGGDGLTREFFRTKFWEDDPQTYGDVVFQPDALPEG
HHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC
VAKTPLTTSEKNALLRYGINEPLLFVGHYWRSGIPAPIRPNLACLDYSAVLYGKLVAYRL
CCCCCCCCCCCCHHEEECCCCCEEEEEHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
DQETQIDPDKFVWVDVQRPEV
CCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA