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The map label for this gene is ppnK [H]

Identifier: 66044930

GI number: 66044930

Start: 1893879

End: 1894769

Strand: Direct

Name: ppnK [H]

Synonym: Psyr_1685

Alternate gene names: 66044930

Gene position: 1893879-1894769 (Clockwise)

Preceding gene: 66044929

Following gene: 66044931

Centisome position: 31.08

GC content: 62.4

Gene sequence:

>891_bases
ATGGAGCAATTTCGCAATATCGGCATCATCGGTCGCCTGGGCAGTGTTCAGGTGCTCGAGACCGTTCGCCGACTCAAGAG
ATTCCTGCTGGACCGCCACCTGCACGTCATTCTCGAAGAGACGATCGCCGAGGTCCTGCCCGGTCATGGCCTGCAGACCT
CATCGCGCAAGATGCTCGGCGAGGTCTGCGACATGGTCATTGTGGTCGGTGGCGACGGCAGTCTGCTGGGCGCGGCGCGG
GCACTGGCCCGGCATAACGTTCCGGTGCTGGGCATCAACCGTGGCAGCCTGGGCTTTCTGACCGACATCCGCCCCGACGA
GCTGGAGGTCAAATGCGCCGAAGTGCTCGACGGGCATTACCTGGTGGAAAACCGCTTTCTGCTCCAGGCCGAAGTGCGTC
GCCACGGCGAGGCCATCGGTCAGGGCGATGCGCTCAACGACGTGGTGCTGCACCCCGGCAAGTCCACGCGCATGATCGAG
TTCGAGATCTACATCGACGGTCAGTTCGTGTGCAGTCAGAAGGCCGACGGCCTGATCGTCGCCACGCCAACCGGTTCGAC
CGCCTACGCGCTGTCGGCAGGCGGGCCGATCATGCACCCCAAGCTCGATGCCATCGTCATTGTGCCGATGTACCCGCATA
CCTTGTCCGGGCGGCCCATCGTGGTCGACGGCAACAGCGAGCTGAAAATCGTGGTGTCCAAGGACATGACCATTTACCCG
CAAGTGTCGTGCGACGGCCAGAATCACTTCACCTGCGCGCCGGGTGACACCATTACGGTCAGCAAGAAGCCGCAGAAACT
GCGTCTGATCCATCCGTTGGATCACAACTATTACGAGGTCTGCCGCACCAAGCTCGGCTGGGGCAGCAAGCTCGGCGGCG
GGGGCGATTAA

Upstream 100 bases:

>100_bases
AGGTCCGCGAAACCCTTTTTAAACCCCGGTTTGCTGCTGTCAGGCCCTTTCGCCCATAATCACGTTTTTAAAGTCGTATC
GAACCCGCAGCAGGAGCCTC

Downstream 100 bases:

>100_bases
TGCTCGATCCGGCGCGTGGCTATGATCTGATCGGTGACGTGCACGGGTGTGCCCATACCCTCGAGCACTTGCTGGAGCTT
CTCGGTTACCGTCTGCAGGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MEQFRNIGIIGRLGSVQVLETVRRLKRFLLDRHLHVILEETIAEVLPGHGLQTSSRKMLGEVCDMVIVVGGDGSLLGAAR
ALARHNVPVLGINRGSLGFLTDIRPDELEVKCAEVLDGHYLVENRFLLQAEVRRHGEAIGQGDALNDVVLHPGKSTRMIE
FEIYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDMTIYP
QVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSKLGGGGD

Sequences:

>Translated_296_residues
MEQFRNIGIIGRLGSVQVLETVRRLKRFLLDRHLHVILEETIAEVLPGHGLQTSSRKMLGEVCDMVIVVGGDGSLLGAAR
ALARHNVPVLGINRGSLGFLTDIRPDELEVKCAEVLDGHYLVENRFLLQAEVRRHGEAIGQGDALNDVVLHPGKSTRMIE
FEIYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDMTIYP
QVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSKLGGGGD
>Mature_296_residues
MEQFRNIGIIGRLGSVQVLETVRRLKRFLLDRHLHVILEETIAEVLPGHGLQTSSRKMLGEVCDMVIVVGGDGSLLGAAR
ALARHNVPVLGINRGSLGFLTDIRPDELEVKCAEVLDGHYLVENRFLLQAEVRRHGEAIGQGDALNDVVLHPGKSTRMIE
FEIYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDMTIYP
QVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSKLGGGGD

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=325, Percent_Identity=28.6153846153846, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1788968, Length=293, Percent_Identity=46.7576791808874, Blast_Score=274, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=31.6666666666667, Blast_Score=129, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=30.1652892561983, Blast_Score=128, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6325068, Length=219, Percent_Identity=32.8767123287671, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI161077047, Length=224, Percent_Identity=38.3928571428571, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573830, Length=224, Percent_Identity=38.3928571428571, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573828, Length=224, Percent_Identity=38.3928571428571, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573826, Length=224, Percent_Identity=38.3928571428571, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573832, Length=224, Percent_Identity=38.3928571428571, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24653422, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281363323, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281363321, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI20129957, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24653424, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32242; Mature: 32242

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFRNIGIIGRLGSVQVLETVRRLKRFLLDRHLHVILEETIAEVLPGHGLQTSSRKMLG
CCCHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EVCDMVIVVGGDGSLLGAARALARHNVPVLGINRGSLGFLTDIRPDELEVKCAEVLDGHY
HHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHCCEE
LVENRFLLQAEVRRHGEAIGQGDALNDVVLHPGKSTRMIEFEIYIDGQFVCSQKADGLIV
EEECEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEEECCEEEECCCCCCEEE
ATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDMTIYP
ECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEECCEEEEE
QVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSKLGGGGD
EEEECCCCCEEECCCCEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEQFRNIGIIGRLGSVQVLETVRRLKRFLLDRHLHVILEETIAEVLPGHGLQTSSRKMLG
CCCHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EVCDMVIVVGGDGSLLGAARALARHNVPVLGINRGSLGFLTDIRPDELEVKCAEVLDGHY
HHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHCCEE
LVENRFLLQAEVRRHGEAIGQGDALNDVVLHPGKSTRMIEFEIYIDGQFVCSQKADGLIV
EEECEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEEECCEEEECCCCCCEEE
ATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDMTIYP
ECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEECCEEEEE
QVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSKLGGGGD
EEEECCCCCEEECCCCEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA