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The map label for this gene is fadH [H]

Identifier: 66044920

GI number: 66044920

Start: 1882468

End: 1884507

Strand: Direct

Name: fadH [H]

Synonym: Psyr_1675

Alternate gene names: 66044920

Gene position: 1882468-1884507 (Clockwise)

Preceding gene: 66044916

Following gene: 66044921

Centisome position: 30.89

GC content: 62.89

Gene sequence:

>2040_bases
ATGACTGCTGCTCATTATCCGCACCTGCTGGCCCCGCTGGACCTGGGCTTCACGACCTTGCGCAACCGCACCCTGATGGG
CTCGATGCACACCGGTCTCGAAGAGCGGCCGGGCGGCTTCGAGCGCATGGCGACCTATTTTGCCGAACGCGCCCGTGGCG
GGGTCGGGCTGATGGTCACCGGCGGCATCGCGCCCAACGAAGAGGGCGGGGTGTATGACGGCGCGGCAAAACTCACCAAC
GCCAAAGAAGCGGAGCGCCATCGTATCGTGACCCAGGCGGTCCACGACGCTGGCGGCAAGATCTGCCTGCAGATCCTCCA
TGCCGGTCGCTACGCCTACAGCCGCAAGCAGGTCGCGCCTAGCGCCATTCAGGCGCCGATCAACCCGTTTACGCCGCGAG
AGCTGGATGAAGAGGGCATCGAAAAGCAGATCGCTGATTTCGTGACCTGCTCGACACTGGCCCGCAGTGCCGGTTATGAC
GGTGTCGAAATCATGGGCTCGGAAGGCTACTTCATCAATCAGTTCCTGGCCGCGCATACCAACCACCGGACCGACCGTTG
GGGCGGCAGCTATGAAAACCGCATGCGGCTGGCGGTCGAGATCGTCAGGCGCGTGCGTGAGGCGGTCGGGGCGCAGTTCA
TCATCATCTTTCGCCTGTCGATGCTCGATCTTGTGGAAGGCGGCAGCAGTTGGGAAGAAATCGTCGAGCTGGCCAAGGCG
GTCGAGCAGGCCGGTGCAACCCTGATCAACACCGGCATCGGCTGGCATGAGGCGCGCATTCCGACCATCGCCACCAAGGT
GCCGCGCGCCGCGTTCAGCAAGGTCACTGCCAAACTGCGCGGCTCGGTGAGCATCCCGCTGATTACCACCAACCGGATCA
ATACCCCGGAAGTTGCCGAGCGCATTCTCAGCGAAGGTGATGCGGACATGGTCTCGATGGCTCGTCCGTTTCTGGCCGAT
CCCGAGTTCGTCAACAAGGCCGCTGCGGGCCATGCCGAACGCATCAACACCTGCATCGGCTGCAACCAGGCCTGCCTCGA
CCACACCTTCGGCGGCAAGCTGACCAGCTGTCTGGTCAATCCGCGTGCCTGCCACGAGACCGAGCTCAATTACCTGCCCA
CCCTGCAGATCAGGAAAATTGCCGTAGTGGGTGCCGGGCCTGCCGGTCTGGCCGCGGCGACCGTCGCCGCACAGCGCGGG
CATGAGGTGACGCTGTTCGATTCGGCCAGCGAAATCGGCGGCCAGTTCAATATCGCCAAGCGCGTGCCGGGCAAGGAGGA
GTTCGCCGAAACGCTGCGTTACTTCCGCAACAAAGTGCAGGAGACGGGTGTTCAGTTACGTCTTGGCAATCGGGTAAAGG
CTGCAGACCTGCTGGACGCAGGCTTTGACGAGGTGATTCTGGCGACCGGCATCGCGCCGCGCACACCGGCCATCCCCGGC
ATCGATAACCCCATGGTGTTGAGCTATCTGGACGTCATATTGCAGCGCAAGCCGGTCGGACGCCGCGTGGCGGTGATAGG
CGCGGGTGGTATCGGTTTCGATGTGTCGGAATTTCTCGTGCATCAGGGCGTGGCCACCAGTCTGGATCGCGAGGCTTTCT
GGAAAGAGTGGGGCATCGATATGACGTTGCAGGCTCGCGGCGGTGTCGCCGGGGTCAAACCCGAAGTCCACGCGCCGGCA
CGCCAGGTGTTTCTGTTGCAGCGCAAGAGCTCCAAGGTGGGCGACGGCCTGGGCAAGACCACCGGCTGGATTCACCGCAC
GGGGCTCAAGAACAAACAGGTGCAGATGCTCAATGCCGTTCAGTACCTGAAAATCGACGATGCAGGGCTGCATATTCGCA
TCGGCGAAGACGGCGAGGAAAAGCTGCTGGCGGTGGATAACGTAGTGATCTGTGCCGGGCAGGACCCGTTGCGTGAGCTG
TATGACGATCTGCTCAACGCCGGGCAAAGCGTGCACCTGATTGGCGGCGCGGATGTTGCCGCAGAGCTGGACGCCAAGCG
GGCCATCGACCAGGGCTCACGTCTGGCCGCCACTCTGTGA

Upstream 100 bases:

>100_bases
TCATTGAGTGTGTGGCGGGATGCGTCTTTACTGGTGCCCATGAACCAGAGGACCCGCAGAGGTCCTTGCTATTCCGTGAT
TGACTCGATGGAGCTTCGCC

Downstream 100 bases:

>100_bases
CAGACAATGCCTGATCAAGGGTTTTGCAACGCAGCCTGCTGACCGGCGAAGACCCTGAAACGGCTTGTCTGTAAACTGCG
GCGCATGATGCTCGACGCCC

Product: NADH:flavin oxidoreductase/NADH oxidase:FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MTAAHYPHLLAPLDLGFTTLRNRTLMGSMHTGLEERPGGFERMATYFAERARGGVGLMVTGGIAPNEEGGVYDGAAKLTN
AKEAERHRIVTQAVHDAGGKICLQILHAGRYAYSRKQVAPSAIQAPINPFTPRELDEEGIEKQIADFVTCSTLARSAGYD
GVEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLAVEIVRRVREAVGAQFIIIFRLSMLDLVEGGSSWEEIVELAKA
VEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVSIPLITTNRINTPEVAERILSEGDADMVSMARPFLAD
PEFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPTLQIRKIAVVGAGPAGLAAATVAAQRG
HEVTLFDSASEIGGQFNIAKRVPGKEEFAETLRYFRNKVQETGVQLRLGNRVKAADLLDAGFDEVILATGIAPRTPAIPG
IDNPMVLSYLDVILQRKPVGRRVAVIGAGGIGFDVSEFLVHQGVATSLDREAFWKEWGIDMTLQARGGVAGVKPEVHAPA
RQVFLLQRKSSKVGDGLGKTTGWIHRTGLKNKQVQMLNAVQYLKIDDAGLHIRIGEDGEEKLLAVDNVVICAGQDPLREL
YDDLLNAGQSVHLIGGADVAAELDAKRAIDQGSRLAATL

Sequences:

>Translated_679_residues
MTAAHYPHLLAPLDLGFTTLRNRTLMGSMHTGLEERPGGFERMATYFAERARGGVGLMVTGGIAPNEEGGVYDGAAKLTN
AKEAERHRIVTQAVHDAGGKICLQILHAGRYAYSRKQVAPSAIQAPINPFTPRELDEEGIEKQIADFVTCSTLARSAGYD
GVEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLAVEIVRRVREAVGAQFIIIFRLSMLDLVEGGSSWEEIVELAKA
VEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVSIPLITTNRINTPEVAERILSEGDADMVSMARPFLAD
PEFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPTLQIRKIAVVGAGPAGLAAATVAAQRG
HEVTLFDSASEIGGQFNIAKRVPGKEEFAETLRYFRNKVQETGVQLRLGNRVKAADLLDAGFDEVILATGIAPRTPAIPG
IDNPMVLSYLDVILQRKPVGRRVAVIGAGGIGFDVSEFLVHQGVATSLDREAFWKEWGIDMTLQARGGVAGVKPEVHAPA
RQVFLLQRKSSKVGDGLGKTTGWIHRTGLKNKQVQMLNAVQYLKIDDAGLHIRIGEDGEEKLLAVDNVVICAGQDPLREL
YDDLLNAGQSVHLIGGADVAAELDAKRAIDQGSRLAATL
>Mature_678_residues
TAAHYPHLLAPLDLGFTTLRNRTLMGSMHTGLEERPGGFERMATYFAERARGGVGLMVTGGIAPNEEGGVYDGAAKLTNA
KEAERHRIVTQAVHDAGGKICLQILHAGRYAYSRKQVAPSAIQAPINPFTPRELDEEGIEKQIADFVTCSTLARSAGYDG
VEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLAVEIVRRVREAVGAQFIIIFRLSMLDLVEGGSSWEEIVELAKAV
EQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVSIPLITTNRINTPEVAERILSEGDADMVSMARPFLADP
EFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPTLQIRKIAVVGAGPAGLAAATVAAQRGH
EVTLFDSASEIGGQFNIAKRVPGKEEFAETLRYFRNKVQETGVQLRLGNRVKAADLLDAGFDEVILATGIAPRTPAIPGI
DNPMVLSYLDVILQRKPVGRRVAVIGAGGIGFDVSEFLVHQGVATSLDREAFWKEWGIDMTLQARGGVAGVKPEVHAPAR
QVFLLQRKSSKVGDGLGKTTGWIHRTGLKNKQVQMLNAVQYLKIDDAGLHIRIGEDGEEKLLAVDNVVICAGQDPLRELY
DDLLNAGQSVHLIGGADVAAELDAKRAIDQGSRLAATL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=671, Percent_Identity=64.2324888226528, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=343, Percent_Identity=30.6122448979592, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17566914, Length=320, Percent_Identity=27.5, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565138, Length=204, Percent_Identity=27.4509803921569, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=224, Percent_Identity=25.4464285714286, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=208, Percent_Identity=26.9230769230769, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=254, Percent_Identity=25.9842519685039, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=209, Percent_Identity=26.7942583732057, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=274, Percent_Identity=25.5474452554745, Blast_Score=79, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=226, Percent_Identity=28.3185840707965, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6325086, Length=224, Percent_Identity=27.6785714285714, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73307; Mature: 73176

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAHYPHLLAPLDLGFTTLRNRTLMGSMHTGLEERPGGFERMATYFAERARGGVGLMVT
CCCCCCCCHHHHHHCCHHHHHCCCEECHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GGIAPNEEGGVYDGAAKLTNAKEAERHRIVTQAVHDAGGKICLQILHAGRYAYSRKQVAP
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
SAIQAPINPFTPRELDEEGIEKQIADFVTCSTLARSAGYDGVEIMGSEGYFINQFLAAHT
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHC
NHRTDRWGGSYENRMRLAVEIVRRVREAVGAQFIIIFRLSMLDLVEGGSSWEEIVELAKA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHH
VEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVSIPLITTNRINTPEVAE
HHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
RILSEGDADMVSMARPFLADPEFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVN
HHHCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHCC
PRACHETELNYLPTLQIRKIAVVGAGPAGLAAATVAAQRGHEVTLFDSASEIGGQFNIAK
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEHH
RVPGKEEFAETLRYFRNKVQETGVQLRLGNRVKAADLLDAGFDEVILATGIAPRTPAIPG
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCC
IDNPMVLSYLDVILQRKPVGRRVAVIGAGGIGFDVSEFLVHQGVATSLDREAFWKEWGID
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
MTLQARGGVAGVKPEVHAPARQVFLLQRKSSKVGDGLGKTTGWIHRTGLKNKQVQMLNAV
EEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCEEECCCCCHHHHHHHHH
QYLKIDDAGLHIRIGEDGEEKLLAVDNVVICAGQDPLRELYDDLLNAGQSVHLIGGADVA
HEEEEECCCEEEEECCCCCCCEEEECCEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHH
AELDAKRAIDQGSRLAATL
HHHHHHHHHCCCCCEECCC
>Mature Secondary Structure 
TAAHYPHLLAPLDLGFTTLRNRTLMGSMHTGLEERPGGFERMATYFAERARGGVGLMVT
CCCCCCCHHHHHHCCHHHHHCCCEECHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GGIAPNEEGGVYDGAAKLTNAKEAERHRIVTQAVHDAGGKICLQILHAGRYAYSRKQVAP
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
SAIQAPINPFTPRELDEEGIEKQIADFVTCSTLARSAGYDGVEIMGSEGYFINQFLAAHT
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHC
NHRTDRWGGSYENRMRLAVEIVRRVREAVGAQFIIIFRLSMLDLVEGGSSWEEIVELAKA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHH
VEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVSIPLITTNRINTPEVAE
HHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
RILSEGDADMVSMARPFLADPEFVNKAAAGHAERINTCIGCNQACLDHTFGGKLTSCLVN
HHHCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHCC
PRACHETELNYLPTLQIRKIAVVGAGPAGLAAATVAAQRGHEVTLFDSASEIGGQFNIAK
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEHH
RVPGKEEFAETLRYFRNKVQETGVQLRLGNRVKAADLLDAGFDEVILATGIAPRTPAIPG
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCC
IDNPMVLSYLDVILQRKPVGRRVAVIGAGGIGFDVSEFLVHQGVATSLDREAFWKEWGID
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
MTLQARGGVAGVKPEVHAPARQVFLLQRKSSKVGDGLGKTTGWIHRTGLKNKQVQMLNAV
EEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCEEECCCCCHHHHHHHHH
QYLKIDDAGLHIRIGEDGEEKLLAVDNVVICAGQDPLRELYDDLLNAGQSVHLIGGADVA
HEEEEECCCEEEEECCCCCCCEEEECCEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHH
AELDAKRAIDQGSRLAATL
HHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]