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The map label for this gene is murB [H]

Identifier: 66044882

GI number: 66044882

Start: 1841112

End: 1842131

Strand: Direct

Name: murB [H]

Synonym: Psyr_1637

Alternate gene names: 66044882

Gene position: 1841112-1842131 (Clockwise)

Preceding gene: 66044881

Following gene: 66044884

Centisome position: 30.21

GC content: 60.98

Gene sequence:

>1020_bases
ATGAGCTTGCAGGTGCAATCCGCGATTTCCCTCAAGCCGTTCAATACGTTCGGTGTGGATGTTCAGGCCCGGTTGTTTGC
CGAAGCGCACAGCGATGATGATGTTCGCGAGGCGCTGGCCTACTCTGCCAGGCATGACGTGCCGCTGCTGGTGATTGGCG
GTGGCAGCAACCTGCTGCTCAGCGCTGACGTGCAGTCGCTGGTGGTGCGCATGGCCAGCCGCGGCATTCGCATCGTGCAC
GAGGACTGTCTTGAGTCGATTGTCGAGGCAGAAGCTGGCGAGCCCTGGCATCCGTTCGTGCAGTCCTGTCTGGAGCTGGG
GCTGGCCGGGCTGGAAAACCTCAGTCTGATCCCAGGCACCGTTGGCGCGGCACCCATGCAGAACATCGGTGCTTATGGCG
TCGAGATCAAGGATGTCTTCCATAGCCTGACTGCGCTGGATCGTGAAACCGGCGAATTGCGCGAGTTTTCTCTGCAGGAC
TGTGCGTTCGGCTACCGCGACAGCGTGTTCAAGCATCAGGTCGCGCGCTGGTTGATCCTGCGTGTGCGTTTCAAGCTCAG
TCGCGTAGCTCGCCTGCACCTCGAATATGGCCCGGTTCGTCAGCGTCTCGACGAGCAGGGTATCGATCGGCCGACGCCGT
TCGATGTCAGCCGTGCGATCTGCGCCATTCGCAGTGAAAAGCTGCCTGACCCTGCGGTGCTGGGCAATGCCGGCAGTTTC
TTCAAAAACCCGATTATCGCTGCCGAACTGTACGCGACGATCAAACAGCAGCACCCAGGCGTGGTCGGCTACCCGCAGGA
CGATGGCCAAGTGAAGCTGGCGGCCGGGTGGCTGATCGAGCAGGCGGGCTGGAAGGGCTATCGCGATGGTGATGCCGGCG
TGCACAAGCTCCAGTCGCTGGTGCTGGTCAACTATGGGCAGGCCAGCGGCCTGCAGCTACTAAGTCTGGCGCGCCGTATC
CAGACCGATATCGCTGAACGTTTTGGTGTCGAGCTGGAAATGGAGCCGAACCTCTACTGA

Upstream 100 bases:

>100_bases
GCGCCACCCGGTGGCGTCGATACCCCCGAAGACCTGGAGCGCGTAAGGCGCTTGCTGGAGGGTTGATGCGCTTCGTCCAG
TGGTCCGGGAAGGCGAGGGC

Downstream 100 bases:

>100_bases
TAGCCTGGGGATGGTCTCTTGTGAGAGGGAGCTCGCTCGCGAAGAGATCAGATCAAGCGCCGCGTATTGAAGATGAGCGT
GGTGCAAGCCTCAATCAACG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLLSADVQSLVVRMASRGIRIVH
EDCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGTVGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQD
CAFGYRDSVFKHQVARWLILRVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSF
FKNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSLVLVNYGQASGLQLLSLARRI
QTDIAERFGVELEMEPNLY

Sequences:

>Translated_339_residues
MSLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLLSADVQSLVVRMASRGIRIVH
EDCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGTVGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQD
CAFGYRDSVFKHQVARWLILRVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSF
FKNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSLVLVNYGQASGLQLLSLARRI
QTDIAERFGVELEMEPNLY
>Mature_338_residues
SLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLLSADVQSLVVRMASRGIRIVHE
DCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGTVGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQDC
AFGYRDSVFKHQVARWLILRVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSFF
KNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSLVLVNYGQASGLQLLSLARRIQ
TDIAERFGVELEMEPNLY

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=327, Percent_Identity=42.5076452599388, Blast_Score=254, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37312; Mature: 37181

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLL
CCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEE
SADVQSLVVRMASRGIRIVHEDCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGT
EHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
VGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQDCAFGYRDSVFKHQVARWLIL
CCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHH
FKNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSL
HHCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHH
VLVNYGQASGLQLLSLARRIQTDIAERFGVELEMEPNLY
HHEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC
>Mature Secondary Structure 
SLQVQSAISLKPFNTFGVDVQARLFAEAHSDDDVREALAYSARHDVPLLVIGGGSNLLL
CCCCCCCCEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEE
SADVQSLVVRMASRGIRIVHEDCLESIVEAEAGEPWHPFVQSCLELGLAGLENLSLIPGT
EHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
VGAAPMQNIGAYGVEIKDVFHSLTALDRETGELREFSLQDCAFGYRDSVFKHQVARWLIL
CCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RVRFKLSRVARLHLEYGPVRQRLDEQGIDRPTPFDVSRAICAIRSEKLPDPAVLGNAGSF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHH
FKNPIIAAELYATIKQQHPGVVGYPQDDGQVKLAAGWLIEQAGWKGYRDGDAGVHKLQSL
HHCCHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHH
VLVNYGQASGLQLLSLARRIQTDIAERFGVELEMEPNLY
HHEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA