Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 66044881

GI number: 66044881

Start: 1840313

End: 1841077

Strand: Direct

Name: kdsB [H]

Synonym: Psyr_1636

Alternate gene names: 66044881

Gene position: 1840313-1841077 (Clockwise)

Preceding gene: 66044880

Following gene: 66044882

Centisome position: 30.2

GC content: 62.75

Gene sequence:

>765_bases
ATGACCGCAGCGTTTACCGTTGTCATTCCTGCGCGCTACGGCTCCAGCCGCTTTCCGGGCAAGCCGCTGAAAACCATTGC
TGGCAAACCCATGGTTCAACTGGTCTGGGAGCAGGCCTGCAAGAGCAGCGCCGAACGCGTGGTGATTGCCACCGACGATG
CACGCATTGTCGAAGCCTGTCAGGCTTTTGGTGCCGAGGTGCTGCTGACGCGCGACGATCACAACTCCGGCACCGATCGT
CTGGCCGAGGTGGCCGCGCAATTGGGCCTGGCGGCTGACGCGATTGTCGTCAATGTGCAGGGCGACGAGCCGATGATCCC
GCCTGCGGTGATCGATCAGGTGGCGTCCAATCTGGCCGCCCATCCCGAAGCCGGCATGTCTACGCTGGCCGAGCCTATCG
ATGACGTGGCCGCGTTGTTCAATCCCAACATCGTCAAGGTGGCTACGGACATCAACGGCCTGGCGCTGACGTTCAGCCGG
GCTCCCTTGCCGTGGGCACGCGATGCGCTTGCAGCAAATCGCGACCAGCTGCCTGCCGGCGTGCCTTATCGTCGGCACAT
CGGGATCTACGCTTATCGTGCGGGTTTCCTGCATGACTTCGTCAGTTGGGGCCCGTGCTGGCTGGAAAACACCGAAAGCC
TGGAACAATTGCGGGCGCTGTGGAATGGCGTGCGAATTCACGTTGCCGACGCGCTTGAAGCGCCACCCGGTGGCGTCGAT
ACCCCCGAAGACCTGGAGCGCGTAAGGCGCTTGCTGGAGGGTTGA

Upstream 100 bases:

>100_bases
TCAGCAAGGGCGCAGGCCTTGCCTATCCGGTGCGCGACGGCATCCCGGTGATGCTCGAAAGCGAAGCTCGCACCCTGAGC
ACCGACGAGCGGCTGGAAAA

Downstream 100 bases:

>100_bases
TGCGCTTCGTCCAGTGGTCCGGGAAGGCGAGGGCATGAGCTTGCAGGTGCAATCCGCGATTTCCCTCAAGCCGTTCAATA
CGTTCGGTGTGGATGTTCAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQACKSSAERVVIATDDARIVEACQAFGAEVLLTRDDHNSGTDR
LAEVAAQLGLAADAIVVNVQGDEPMIPPAVIDQVASNLAAHPEAGMSTLAEPIDDVAALFNPNIVKVATDINGLALTFSR
APLPWARDALAANRDQLPAGVPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVD
TPEDLERVRRLLEG

Sequences:

>Translated_254_residues
MTAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQACKSSAERVVIATDDARIVEACQAFGAEVLLTRDDHNSGTDR
LAEVAAQLGLAADAIVVNVQGDEPMIPPAVIDQVASNLAAHPEAGMSTLAEPIDDVAALFNPNIVKVATDINGLALTFSR
APLPWARDALAANRDQLPAGVPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVD
TPEDLERVRRLLEG
>Mature_253_residues
TAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQACKSSAERVVIATDDARIVEACQAFGAEVLLTRDDHNSGTDRL
AEVAAQLGLAADAIVVNVQGDEPMIPPAVIDQVASNLAAHPEAGMSTLAEPIDDVAALFNPNIVKVATDINGLALTFSRA
PLPWARDALAANRDQLPAGVPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVDT
PEDLERVRRLLEG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=246, Percent_Identity=55.2845528455285, Blast_Score=267, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27333; Mature: 27202

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQACKSSAERVVIATDDARIVEAC
CCCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
QAFGAEVLLTRDDHNSGTDRLAEVAAQLGLAADAIVVNVQGDEPMIPPAVIDQVASNLAA
HHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
HPEAGMSTLAEPIDDVAALFNPNIVKVATDINGLALTFSRAPLPWARDALAANRDQLPAG
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCC
VPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVD
CCHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
TPEDLERVRRLLEG
CHHHHHHHHHHHCC
>Mature Secondary Structure 
TAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQACKSSAERVVIATDDARIVEAC
CCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
QAFGAEVLLTRDDHNSGTDRLAEVAAQLGLAADAIVVNVQGDEPMIPPAVIDQVASNLAA
HHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
HPEAGMSTLAEPIDDVAALFNPNIVKVATDINGLALTFSRAPLPWARDALAANRDQLPAG
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCC
VPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVD
CCHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
TPEDLERVRRLLEG
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA