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The map label for this gene is nadA [H]

Identifier: 66044788

GI number: 66044788

Start: 1735836

End: 1736894

Strand: Direct

Name: nadA [H]

Synonym: Psyr_1542

Alternate gene names: 66044788

Gene position: 1735836-1736894 (Clockwise)

Preceding gene: 66044787

Following gene: 66044790

Centisome position: 28.49

GC content: 60.81

Gene sequence:

>1059_bases
ATGACACAGATCTCCGAACGTTTCCTGGTGCAGGCGCATCTCGATGCCAAACAGCCCAGGACGTTGAGCCCGGCAGAGCA
GGCGCGTTACCGTGCCGACATTGCTGCTGAACTCAAGAAGCAGGACGCCGTGCTGGTTGCTCACTATTACTGTGATCCGG
TTATCCAGGCGCTGGCCGAGGAGACCGGTGGCTGCGTGGCCGACTCCCTGGAAATGGCGCGCTTCAGCAATAACCACGCG
GCCAGCACTGTATTGGTGGCGGGTGTGCGTTTCATGGGCGAAACCGCGAAGATCCTCAACCCGGAAAAACGCGTGTTCAT
GCCGACGCTTGAAGCCACCTGCTCGCTTGACGTGGGGTGCCCGGTCGACGAGTTTTCCGCCTTTTGCGACCAGCACCCGG
AACGTACCGTGGTGGTGTATGCCAACACCTCGGCAGCCGTCAAAGCCCGCGCGGACTGGGTGGTGACCTCAGGCTGTGCG
CTGGAAATCGTTGAGAGCCTGATGGACAACGGTGAGAAAATCATCTGGGCGCCAGACAAGCACCTGGGTCGCTACATCCA
GCGTGAAACCGGTGCCGACATGCTGTTGTGGGACGGTGCCTGCATCGTTCACGAAGAGTTCAAGTCCAAGCAGCTCGAAG
ACATGAAAGCCCTGTACCCCGAGGCGGCGATTCTGGTTCACCCGGAGTCGCCGGAAGCGGTCATCGAGCTGGCTGACGTG
GTCGGCTCGACCAGTCAGATGATTGCGGCAGCGCAACGCCTGCCCAACAAGACGTTCATCGTTGCCACTGACCGGGGCAT
CTTCTACAAGATGCAGCAGCTGTGCCCGGACAAGATCTTCATCGAGGCGCCTACGGCCGGCAACGGCGCGGCGTGCCGGA
GTTGTGCACATTGCCCATGGATGGCGATGAATACGCTTGAACGCACCTTGCAGTGCCTGCGTGAGGGCAGTAACGAGATA
TTCGTCGACCCGGCGCTGATCCCCCATGCTGTACGCCCCTTGCAGCGCATGCTGGACTTCACTCAGGCAGCGCGTTTGCG
ACAGGCCGGCAACGCCTGA

Upstream 100 bases:

>100_bases
CTTTGTACAGATGGCGCAGCCTCTGTCAGGCTTTTTTTATTGCCTGTATTTCGGGTGTAAACTTGCCTTTCGCGCACTGG
CGCTTTCAGGTCCCGTGAAC

Downstream 100 bases:

>100_bases
CAGCGGTCATGAAAAAGCCCGACTGAAGCGTCGGGCTTTTCATTGTTGTACGTGTCAAGCCGTCTTGCGACGCCGGACGA
TCAGTTCATCATGTCCTTGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTQISERFLVQAHLDAKQPRTLSPAEQARYRADIAAELKKQDAVLVAHYYCDPVIQALAEETGGCVADSLEMARFSNNHA
ASTVLVAGVRFMGETAKILNPEKRVFMPTLEATCSLDVGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSGCA
LEIVESLMDNGEKIIWAPDKHLGRYIQRETGADMLLWDGACIVHEEFKSKQLEDMKALYPEAAILVHPESPEAVIELADV
VGSTSQMIAAAQRLPNKTFIVATDRGIFYKMQQLCPDKIFIEAPTAGNGAACRSCAHCPWMAMNTLERTLQCLREGSNEI
FVDPALIPHAVRPLQRMLDFTQAARLRQAGNA

Sequences:

>Translated_352_residues
MTQISERFLVQAHLDAKQPRTLSPAEQARYRADIAAELKKQDAVLVAHYYCDPVIQALAEETGGCVADSLEMARFSNNHA
ASTVLVAGVRFMGETAKILNPEKRVFMPTLEATCSLDVGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSGCA
LEIVESLMDNGEKIIWAPDKHLGRYIQRETGADMLLWDGACIVHEEFKSKQLEDMKALYPEAAILVHPESPEAVIELADV
VGSTSQMIAAAQRLPNKTFIVATDRGIFYKMQQLCPDKIFIEAPTAGNGAACRSCAHCPWMAMNTLERTLQCLREGSNEI
FVDPALIPHAVRPLQRMLDFTQAARLRQAGNA
>Mature_351_residues
TQISERFLVQAHLDAKQPRTLSPAEQARYRADIAAELKKQDAVLVAHYYCDPVIQALAEETGGCVADSLEMARFSNNHAA
STVLVAGVRFMGETAKILNPEKRVFMPTLEATCSLDVGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSGCAL
EIVESLMDNGEKIIWAPDKHLGRYIQRETGADMLLWDGACIVHEEFKSKQLEDMKALYPEAAILVHPESPEAVIELADVV
GSTSQMIAAAQRLPNKTFIVATDRGIFYKMQQLCPDKIFIEAPTAGNGAACRSCAHCPWMAMNTLERTLQCLREGSNEIF
VDPALIPHAVRPLQRMLDFTQAARLRQAGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=332, Percent_Identity=67.4698795180723, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38752; Mature: 38621

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQISERFLVQAHLDAKQPRTLSPAEQARYRADIAAELKKQDAVLVAHYYCDPVIQALAE
CCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
ETGGCVADSLEMARFSNNHAASTVLVAGVRFMGETAKILNPEKRVFMPTLEATCSLDVGC
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCHHEEEECHHHHEEECCCC
PVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSGCALEIVESLMDNGEKIIWAPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECCHHHHHHHHHHCCCCEEEECCCH
HLGRYIQRETGADMLLWDGACIVHEEFKSKQLEDMKALYPEAAILVHPESPEAVIELADV
HHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
VGSTSQMIAAAQRLPNKTFIVATDRGIFYKMQQLCPDKIFIEAPTAGNGAACRSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCCH
MAMNTLERTLQCLREGSNEIFVDPALIPHAVRPLQRMLDFTQAARLRQAGNA
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQISERFLVQAHLDAKQPRTLSPAEQARYRADIAAELKKQDAVLVAHYYCDPVIQALAE
CCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
ETGGCVADSLEMARFSNNHAASTVLVAGVRFMGETAKILNPEKRVFMPTLEATCSLDVGC
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCHHEEEECHHHHEEECCCC
PVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSGCALEIVESLMDNGEKIIWAPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECCHHHHHHHHHHCCCCEEEECCCH
HLGRYIQRETGADMLLWDGACIVHEEFKSKQLEDMKALYPEAAILVHPESPEAVIELADV
HHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
VGSTSQMIAAAQRLPNKTFIVATDRGIFYKMQQLCPDKIFIEAPTAGNGAACRSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCCH
MAMNTLERTLQCLREGSNEIFVDPALIPHAVRPLQRMLDFTQAARLRQAGNA
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]