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The map label for this gene is umuD [H]

Identifier: 66044672

GI number: 66044672

Start: 1612506

End: 1612940

Strand: Direct

Name: umuD [H]

Synonym: Psyr_1424

Alternate gene names: 66044672

Gene position: 1612506-1612940 (Clockwise)

Preceding gene: 66044668

Following gene: 66044673

Centisome position: 26.46

GC content: 52.18

Gene sequence:

>435_bases
ATGAGCGTAGTCATTCTTGGTCCGTTGTCTGAAGGGGGTATCAAGCTACCGCTCTACTCATTTCAGGTGCCAGCTGGGTT
TGCTTCTCCCGCTGTCGATTACATCGAGAAGCACGTGTCCCTAGACGAACTGGCCGAGGTACGGGCACCGCATGTCTACC
TGGCGAAAATTCTCGGAGACAGCATGATTGGGGCAGGTATTTTTGATAAGGATTTGATCGTCGTTGATCGCAGTCGCACT
GCCGAGCATGGAGAGATCGTTGTGGCAGCGCTTAATAATTCGGAACCGATTTGCAAGCGGCTGTTCATGATGGATGGGGT
TGTCAAACTTCAATCCGAAAATAGTGCCTACCCGTCCAAGCACATCCTGGAGGGTGACAACCTCGTCATCTGGGGCGTAG
TGAACTACAGCATGCGCCGTCATGGAAAAGCGTGA

Upstream 100 bases:

>100_bases
ATGTCACTCGTCGAAAATGCCTTTCAGTACGATTGACCGCGCGCGGGCCAAAGAGTTAACTGTATATATATACAGCTAAC
TTTATAGAAAGGTCTTCATC

Downstream 100 bases:

>100_bases
GGCTGTCTTCGCGCTAATCGACTGCAATTGCTTCTATGCCAGCTGCGAGCGTGTTTTTCGTCCAGATCTGGAGAAAACGC
CCATCGTGGTACTCAGCAAT

Product: peptidase S24, S26A and S26B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSVVILGPLSEGGIKLPLYSFQVPAGFASPAVDYIEKHVSLDELAEVRAPHVYLAKILGDSMIGAGIFDKDLIVVDRSRT
AEHGEIVVAALNNSEPICKRLFMMDGVVKLQSENSAYPSKHILEGDNLVIWGVVNYSMRRHGKA

Sequences:

>Translated_144_residues
MSVVILGPLSEGGIKLPLYSFQVPAGFASPAVDYIEKHVSLDELAEVRAPHVYLAKILGDSMIGAGIFDKDLIVVDRSRT
AEHGEIVVAALNNSEPICKRLFMMDGVVKLQSENSAYPSKHILEGDNLVIWGVVNYSMRRHGKA
>Mature_143_residues
SVVILGPLSEGGIKLPLYSFQVPAGFASPAVDYIEKHVSLDELAEVRAPHVYLAKILGDSMIGAGIFDKDLIVVDRSRTA
EHGEIVVAALNNSEPICKRLFMMDGVVKLQSENSAYPSKHILEGDNLVIWGVVNYSMRRHGKA

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=121, Percent_Identity=42.1487603305785, Blast_Score=86, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 15704; Mature: 15573

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVILGPLSEGGIKLPLYSFQVPAGFASPAVDYIEKHVSLDELAEVRAPHVYLAKILGD
CEEEEEECCCCCCEECEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCC
SMIGAGIFDKDLIVVDRSRTAEHGEIVVAALNNSEPICKRLFMMDGVVKLQSENSAYPSK
HHHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCC
HILEGDNLVIWGVVNYSMRRHGKA
EEECCCCEEEEEEECCHHHHCCCC
>Mature Secondary Structure 
SVVILGPLSEGGIKLPLYSFQVPAGFASPAVDYIEKHVSLDELAEVRAPHVYLAKILGD
EEEEEECCCCCCEECEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCC
SMIGAGIFDKDLIVVDRSRTAEHGEIVVAALNNSEPICKRLFMMDGVVKLQSENSAYPSK
HHHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCC
HILEGDNLVIWGVVNYSMRRHGKA
EEECCCCEEEEEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]