Click here to switch to the map view.

The map label for this gene is ruvA [H]

Identifier: 66044657

GI number: 66044657

Start: 1595560

End: 1596168

Strand: Direct

Name: ruvA [H]

Synonym: Psyr_1409

Alternate gene names: 66044657

Gene position: 1595560-1596168 (Clockwise)

Preceding gene: 66044656

Following gene: 66044658

Centisome position: 26.18

GC content: 59.93

Gene sequence:

>609_bases
GTGATTGGACGTTTACGCGGCTCTCTCGCCGAAAAGCAGCCTCCGCATCTGGTGCTGGATGTCAACGGTGTCGGCTATGA
GGTGGAAGTGCCGATGACCACCCTGTACCGGCTGCCGCATGTTGGCGAGACGGTGACTTTGCACACCCACCTGGTGGTCC
GCGAGGACGCGCACCTTTTGTACGGCTTCTACGAAAAACGCGAGCGCGAACTGTTTCGTGAGCTGATCCGGCTCAATGGC
GTCGGCCCCAAGCTGGCACTGGCGCTGATGTCCGGTCTGGAAGTCGATGAGCTGGTACGTTGCGTACAGGCGCAGGACAC
GTCGGCGCTGACGCGTATCCCCGGTGTGGGCAAGAAGACTGCCGAGCGGCTGCTGGTCGAGCTCAAGGATCGTTTCAAGG
CCTGGGAGGCCTTGCCAGGCACCTTTACGCTGGTTTCCAATGGTCCCAATCAGGCTGAGCCTGTGGCATCGGCAGAGTCC
GATGCGGTCAGCGCACTGATTTCGCTGGGCTACAAACCTCAGGAGGCGAGCAAGGCTGTCTCCGCCATCAAGGAAAAAGA
TTTGAGCAGTGCGGATCTGATTCGCCGTGCGTTGAAGGGGATGGGTTAA

Upstream 100 bases:

>100_bases
CGCTTGCGGCTCTAGAGGCATTATATGTCCGCTTATTTTCTATGATGACGGTGTTCAACTTCTTCGCGCGAGCGACAGGC
AACACGAAAGGATCTGAAAC

Downstream 100 bases:

>100_bases
GTGATAGACGCCGACCGTCTGATAACTGCCACTGGTGGCCGTGATCGTGATGAACAGATGGACCGCGCGATTCGGCCACT
GAGCCTTGCGGATTACATCG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MIGRLRGSLAEKQPPHLVLDVNGVGYEVEVPMTTLYRLPHVGETVTLHTHLVVREDAHLLYGFYEKRERELFRELIRLNG
VGPKLALALMSGLEVDELVRCVQAQDTSALTRIPGVGKKTAERLLVELKDRFKAWEALPGTFTLVSNGPNQAEPVASAES
DAVSALISLGYKPQEASKAVSAIKEKDLSSADLIRRALKGMG

Sequences:

>Translated_202_residues
MIGRLRGSLAEKQPPHLVLDVNGVGYEVEVPMTTLYRLPHVGETVTLHTHLVVREDAHLLYGFYEKRERELFRELIRLNG
VGPKLALALMSGLEVDELVRCVQAQDTSALTRIPGVGKKTAERLLVELKDRFKAWEALPGTFTLVSNGPNQAEPVASAES
DAVSALISLGYKPQEASKAVSAIKEKDLSSADLIRRALKGMG
>Mature_202_residues
MIGRLRGSLAEKQPPHLVLDVNGVGYEVEVPMTTLYRLPHVGETVTLHTHLVVREDAHLLYGFYEKRERELFRELIRLNG
VGPKLALALMSGLEVDELVRCVQAQDTSALTRIPGVGKKTAERLLVELKDRFKAWEALPGTFTLVSNGPNQAEPVASAES
DAVSALISLGYKPQEASKAVSAIKEKDLSSADLIRRALKGMG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=55.3921568627451, Blast_Score=217, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22124; Mature: 22124

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGSLAEKQPPHLVLDVNGVGYEVEVPMTTLYRLPHVGETVTLHTHLVVREDAHLL
CCCCHHCHHHCCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCEEEEEEEEEEECCCHHH
YGFYEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSALTRIPGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERLLVELKDRFKAWEALPGTFTLVSNGPNQAEPVASAESDAVSALISLGYKPQEASKAV
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
SAIKEKDLSSADLIRRALKGMG
HHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIGRLRGSLAEKQPPHLVLDVNGVGYEVEVPMTTLYRLPHVGETVTLHTHLVVREDAHLL
CCCCHHCHHHCCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCEEEEEEEEEEECCCHHH
YGFYEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSALTRIPGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERLLVELKDRFKAWEALPGTFTLVSNGPNQAEPVASAESDAVSALISLGYKPQEASKAV
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
SAIKEKDLSSADLIRRALKGMG
HHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA