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The map label for this gene is dinB

Identifier: 66044645

GI number: 66044645

Start: 1582602

End: 1583666

Strand: Direct

Name: dinB

Synonym: Psyr_1397

Alternate gene names: 66044645

Gene position: 1582602-1583666 (Clockwise)

Preceding gene: 66044642

Following gene: 66044649

Centisome position: 25.97

GC content: 60.56

Gene sequence:

>1065_bases
ATGACGCAGCGCAAAATCATCCACATCGACTGTGACTGCTTTTATGCAGCCATTGAAATGCGTGACGAGCCCGACCTCGC
CGGCAAACCGTTGGCGGTAGGCGGCTCTGCGGAGCGGCGCGGGGTGATTGCGACCTGTAATTACGAGGCGCGCGCCTATG
GCGTGCGTTCGGCCATGTCGTCCCGGCATGCGCTCAAGCTCTGCCCGGACCTGACCATCGTCAAGCCGCGCATGGATGCC
TATAAAGAAGCGTCGCGGGAAATCCACACGATCTTTCGCGATTACACCGACCTTATAGAGCCGCTGTCTCTGGATGAGGC
CTTTCTGGATGTGTCCGAGGCCGGGCACTTTTCCGGCAGCGCCACGCGCATCGCGCAGGACATCCGTCGTCGGGTCTCGA
ATCAATTGCACATCACCGTGTCGGCGGGCGTTGCGCCCAACAAGTTTCTCGCCAAGATCGCCAGCGACTGGAAAAAGCCC
AACGGGTTGTTCGTCATTACGCCGGATCAGGTCGAGGAATTCGTCGCTTCCCTGCCAGTCACCAAGCTTCATGGCGTAGG
CAAAGTCACCGCAGACAAACTCGGCCGGCTGGGTATCGTCGACTGCGCCGACCTGCGAAGCCGCAGCAAGCTCGCGCTGG
TCCGGGAGTTCGGCAGCTTCGGTGAGCGCCTCTGGAGTCTGGCGCACGGCATTGATGACCGACCGGTGCAGAATGACAGC
CGACGTCAGTCAGTCAGCGTTGAAAATACCTACGACACGGATCTGCCTGATCTGGCGGCCTGCCTGGAAAAGCTGCCCGA
CCTGCTGGAAACCTTGAGTGGCCGGATGGCCAGAATGGAAGGGCAGTACCGGCCCGGCAAGCCGTTCGTCAAGGTGAAGT
TTCATGACTTTACGCAGACGACTCTGGAGCAGTCCGGAGCCGGAAGGGATCTGGGCAGTTATGAACAGTTGCTGGCTCAG
GCGTTCGCCCGCGGTGGCAAGCCGGTCAGGTTGCTGGGCATAGGCGTGCGCCTGCACGACCTGCGTGCAGCCCATGAGCA
GCTGGAATTGTTCTCTCGACAATGA

Upstream 100 bases:

>100_bases
TTTTGACTACTTTTCGTGGCGGCCTTTCGCATCATTGGATGTTACTTGGCGGCACGAATGAGATACTGCCCGGCCATTGA
TTGCAAAATCCCATCAGGTC

Downstream 100 bases:

>100_bases
CTGGCCGCGGTTAAACGCCGCGGCCTTTCATGTTGCGGGATTTTTTTACTGGCTCTGGGCAGGAACGGCGACCAGGCGGC
CAGCGTCTCTGGCGAGCGAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTQRKIIHIDCDCFYAAIEMRDEPDLAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMSSRHALKLCPDLTIVKPRMDA
YKEASREIHTIFRDYTDLIEPLSLDEAFLDVSEAGHFSGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKP
NGLFVITPDQVEEFVASLPVTKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDS
RRQSVSVENTYDTDLPDLAACLEKLPDLLETLSGRMARMEGQYRPGKPFVKVKFHDFTQTTLEQSGAGRDLGSYEQLLAQ
AFARGGKPVRLLGIGVRLHDLRAAHEQLELFSRQ

Sequences:

>Translated_354_residues
MTQRKIIHIDCDCFYAAIEMRDEPDLAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMSSRHALKLCPDLTIVKPRMDA
YKEASREIHTIFRDYTDLIEPLSLDEAFLDVSEAGHFSGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKP
NGLFVITPDQVEEFVASLPVTKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDS
RRQSVSVENTYDTDLPDLAACLEKLPDLLETLSGRMARMEGQYRPGKPFVKVKFHDFTQTTLEQSGAGRDLGSYEQLLAQ
AFARGGKPVRLLGIGVRLHDLRAAHEQLELFSRQ
>Mature_353_residues
TQRKIIHIDCDCFYAAIEMRDEPDLAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMSSRHALKLCPDLTIVKPRMDAY
KEASREIHTIFRDYTDLIEPLSLDEAFLDVSEAGHFSGSATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKPN
GLFVITPDQVEEFVASLPVTKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDSR
RQSVSVENTYDTDLPDLAACLEKLPDLLETLSGRMARMEGQYRPGKPFVKVKFHDFTQTTLEQSGAGRDLGSYEQLLAQA
FARGGKPVRLLGIGVRLHDLRAAHEQLELFSRQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=355, Percent_Identity=30.1408450704225, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI7706681, Length=356, Percent_Identity=30.0561797752809, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=31.8471337579618, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=47.2222222222222, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI5729982, Length=307, Percent_Identity=27.3615635179153, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1786425, Length=342, Percent_Identity=50.2923976608187, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI1787432, Length=205, Percent_Identity=27.8048780487805, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=399, Percent_Identity=29.5739348370927, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=260, Percent_Identity=27.6923076923077, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=337, Percent_Identity=27.0029673590504, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=37.9032258064516, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=332, Percent_Identity=28.3132530120482, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=30.8771929824561, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=30.8771929824561, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=33.6134453781513, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_PSEU2 (Q4ZWM4)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_234486.1
- HSSP:   P96022
- ProteinModelPortal:   Q4ZWM4
- SMR:   Q4ZWM4
- STRING:   Q4ZWM4
- GeneID:   3366894
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_1397
- NMPDR:   fig|205918.4.peg.1882
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QNDSRRQ
- ProtClustDB:   PRK02406
- BioCyc:   PSYR205918:PSYR_1397-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39305; Mature: 39174

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRKIIHIDCDCFYAAIEMRDEPDLAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMS
CCCCEEEEEECHHEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHH
SRHALKLCPDLTIVKPRMDAYKEASREIHTIFRDYTDLIEPLSLDEAFLDVSEAGHFSGS
CCCHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
ATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKPNGLFVITPDQVEEFVASLPV
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCH
TKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDS
HHHCCCCCCCHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RRQSVSVENTYDTDLPDLAACLEKLPDLLETLSGRMARMEGQYRPGKPFVKVKFHDFTQT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
TLEQSGAGRDLGSYEQLLAQAFARGGKPVRLLGIGVRLHDLRAAHEQLELFSRQ
HHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQRKIIHIDCDCFYAAIEMRDEPDLAGKPLAVGGSAERRGVIATCNYEARAYGVRSAMS
CCCEEEEEECHHEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHH
SRHALKLCPDLTIVKPRMDAYKEASREIHTIFRDYTDLIEPLSLDEAFLDVSEAGHFSGS
CCCHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
ATRIAQDIRRRVSNQLHITVSAGVAPNKFLAKIASDWKKPNGLFVITPDQVEEFVASLPV
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCH
TKLHGVGKVTADKLGRLGIVDCADLRSRSKLALVREFGSFGERLWSLAHGIDDRPVQNDS
HHHCCCCCCCHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RRQSVSVENTYDTDLPDLAACLEKLPDLLETLSGRMARMEGQYRPGKPFVKVKFHDFTQT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
TLEQSGAGRDLGSYEQLLAQAFARGGKPVRLLGIGVRLHDLRAAHEQLELFSRQ
HHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA