Click here to switch to the map view.

The map label for this gene is mprF [H]

Identifier: 66044644

GI number: 66044644

Start: 1578990

End: 1581632

Strand: Reverse

Name: mprF [H]

Synonym: Psyr_1396

Alternate gene names: 66044644

Gene position: 1581632-1578990 (Counterclockwise)

Preceding gene: 66044646

Following gene: 66044643

Centisome position: 25.96

GC content: 62.43

Gene sequence:

>2643_bases
ATGCGCGACAACATGTCCGATTCCAATGAAACCATTGATGCAGAGCAACCCGTCAGCCCCCCGCGCCATAACTGGCGGGA
GCTGCTGAGCAAATACCGACAGCCCATCGGGCTGGCGGTGATGCTGCTGTTGTTCAGCCTGGCCCTTATAGCCTGCCGCC
ACATGCTGGTCGAAATGGACTGGTATGCGCTGCACGACTCGCTGTTCGCAGTCCCCCTGCCCGCCCTGGGCGGTGCGCTG
CTCGCGGCAATCGTCGGCTATATCATTCTGATGGGCTATGAACTGTCCGCCAGTCGATACGCCAATGTCGACCTGCCTAT
CAAGACGCTGCTTCTCGGCGGCTTCACCTCATTTGCCATCGGCAATGCGGTCGGCCTGTCGATGCTGTCCGGTGGCTCGG
TGCGCTACAGGCTTTATTCACGCCATGGCGTAGGCGCAATTGAAATCGCCCGCATGACCGTGTTCGCCAGCCTGTCACTG
GGCTGTGCGCTGCCGCCGCTGGCTGCACTGGCCACGCTGAGCAACCTGTCAGGCGCGTCACTGGCCCTCAAGCTTCCCGT
CGACGTGCTGGCTGTAGTCGCTACAGCGGTGTTGATCGGCAGCCTGCTGCTGGCGGTGTTAATCTACCGTCGACGCCTGC
CGGAACAGGACATCCCGCACAATATTCTGGTTCGTCTCGGTCGTCGCACCTTGCGCCTGCCGGATTTGAAGCTGACGCTG
ATTCAGCTGGTGATCACCGCGCTGGACGTCGCCGCCGCAGCGATGGTGCTGTACCTGCTGCTGCCGCATGCGCCGCCGCT
GGGTGCATTCATCCTTATCTACCTGCTGGCGCTCGCTGCTGGCGTGCTCAGCCATGTGCCTGGTGGCGTCGGCGTGTTCG
AGGCGATTCTGCTCGCAGCCTTTGCCAACGAACTGGGTGCCGCCCCGCTCGCCGCTGCACTGCTGCTGTACCGCCTGATC
TACGTGATCCTGCCGCTGCTGCTGGCCTGCCTTACCCTGCTGTTCACCGAGGCTCAGCGCCTGCTACCGACCCGGCAGGC
CATGCGCGTCGCCTCAGGGCTGGCGGCACCGATTCTGGCACTACTGGTTTTCTTGTCGGGGGTGGTGCTGCTCTTCTCTG
GTGCCACCCCTGAAATCGATACCCGTCTGGAAAACGTCGGCTTCATGATCCCGCATCGACTGATCGATGCGTCGCACTTT
GGAGCCAGTCTGGTGGGCGTGCTGTGCCTGCTGCTCGCCCAGGGCCTGCGTCGCCGGCTGTCGGCTGCCTGGATGCTGAC
CTCTATCCTGCTGCTGGTAGGTGCAGTGCTGTCGATACTCAAGGGCTTCGACTGGGAAGAAGCCAGCATGCTGCTGCTGA
CCGCCTGCCTGCTGCTGACCTTCCGCCGTTCGTTCTACCGTCCAAGCCGCCTGCTAGAGCTGCCGTTCTCGCCGGTCTAC
CTGATTGCCAGCATCTGTGTGGTCGGCGCCTCGATCTGGCTGCTGCTGTTCGCCTATCAGGACGTGCCCTACAGTCACCA
GTTGTGGTGGCAGTTCACCCTCGATGCAGACGCCCCGCGCGGCCTGCGTTCGGCGCTCGGCAGCGCCGTGCTGCTGGTAG
TGGTTTCGCTGACCTGGTTACTGCGTACTGCCAGACCGGTCATCAAGCTGCCCGACGCCGAGGATCTGGACAAGGCGGCC
GAGATCCTCAAGGCCTCCAAACAGCCCGATGGCGGCCTGGTGCTGACCGGCGACAAGGCGATCCTGTTCCATCCGGCCGG
CAATGCGTTCCTGATGTACTCGCATCGCGGCCGCAGTCTGGTAGCACTTTACGACCCGATCGGCCCCACACAACAGCGTG
CCGAGCTGATCTGGCAGTTCCGCGACCTGTGCGACGTGCACCATGCGCGCCCGGTGTTCTATCAGGTACGTGCAGAAAAC
CTGCCGTTCTACATGGACATCGGTCTCACGGCCATCAAGCTGGGTGAAGAAGCGCGCGTCGACCTGCATCGCTTCGACAT
CGACGCCAAGGGCAAGGAGATGAAAGACCTGCGTTACACCTGGAACCGGGGTGGCCGCGACGGTCTTTCGCTGGAGATCT
ACGAACCGGGCCAGGCGCCGATCGACGAGCTGAAAGTGATTTCCGACGCCTGGCTGACGGGCAAGAATGTCCGCGAAAAA
GGCTTTTCGCTGGGCCGTTTCAGCACTGAGTACCTGAAGTACTTCCGCATTGCCATCGTGCACTTCCAGGGCAAGCCGGT
CGCGTTCTCCAACCTGCTGGAAACCACCAGCCCGGAACTGGCCAGCCTGGACCTGATGCGCTCCCACCCGGATGCACCCA
AGCTGACCATGGAATTCATGATGGTCGGCCTGATTCTGCATTACAAAGCCCAGGGCTACGCGCGCTTCAGCCTGGGCATG
GTGCCTTTATCGGGCCTGCAGCCACGACGCGGCGCACCCATCACCCAGCGTCTGGGTTCGATGATCTTCCGCCGTGGCGA
ACAGCTGTACAACTTCCAGGGGCTGCGTCGCTTCAAGGACAAGTTCCAGCCCGATTGGGAACCTCGTTATATGGCCGTGC
CTGCCGGACTCGATCCGCTTGTGGCACTGGCTGACACCGCCGCCCTGATTGCGGGCGGCCTGACTGGATTGGTGAAACGC
TGA

Upstream 100 bases:

>100_bases
TAGACGTTGACGCGCTAACATCCTGAAATATTTTCTGCGTAGGGATTGGTAACTTGGCTGCATACCTCCATCCTGTCGCG
CACGATCCAAGGAGTGATTG

Downstream 100 bases:

>100_bases
TGATTCGACGCTCCTGGCGCCTTTTGCTCGCAGCTCTGGTAATTGTTCTTTTAATCGTAGCGCTGGGGGTCTGGGTCTGG
ACCCGCCCCGCTCCGCCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase; Multiple peptide resistance factor [H]

Number of amino acids: Translated: 880; Mature: 880

Protein sequence:

>880_residues
MRDNMSDSNETIDAEQPVSPPRHNWRELLSKYRQPIGLAVMLLLFSLALIACRHMLVEMDWYALHDSLFAVPLPALGGAL
LAAIVGYIILMGYELSASRYANVDLPIKTLLLGGFTSFAIGNAVGLSMLSGGSVRYRLYSRHGVGAIEIARMTVFASLSL
GCALPPLAALATLSNLSGASLALKLPVDVLAVVATAVLIGSLLLAVLIYRRRLPEQDIPHNILVRLGRRTLRLPDLKLTL
IQLVITALDVAAAAMVLYLLLPHAPPLGAFILIYLLALAAGVLSHVPGGVGVFEAILLAAFANELGAAPLAAALLLYRLI
YVILPLLLACLTLLFTEAQRLLPTRQAMRVASGLAAPILALLVFLSGVVLLFSGATPEIDTRLENVGFMIPHRLIDASHF
GASLVGVLCLLLAQGLRRRLSAAWMLTSILLLVGAVLSILKGFDWEEASMLLLTACLLLTFRRSFYRPSRLLELPFSPVY
LIASICVVGASIWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSALGSAVLLVVVSLTWLLRTARPVIKLPDAEDLDKAA
EILKASKQPDGGLVLTGDKAILFHPAGNAFLMYSHRGRSLVALYDPIGPTQQRAELIWQFRDLCDVHHARPVFYQVRAEN
LPFYMDIGLTAIKLGEEARVDLHRFDIDAKGKEMKDLRYTWNRGGRDGLSLEIYEPGQAPIDELKVISDAWLTGKNVREK
GFSLGRFSTEYLKYFRIAIVHFQGKPVAFSNLLETTSPELASLDLMRSHPDAPKLTMEFMMVGLILHYKAQGYARFSLGM
VPLSGLQPRRGAPITQRLGSMIFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR

Sequences:

>Translated_880_residues
MRDNMSDSNETIDAEQPVSPPRHNWRELLSKYRQPIGLAVMLLLFSLALIACRHMLVEMDWYALHDSLFAVPLPALGGAL
LAAIVGYIILMGYELSASRYANVDLPIKTLLLGGFTSFAIGNAVGLSMLSGGSVRYRLYSRHGVGAIEIARMTVFASLSL
GCALPPLAALATLSNLSGASLALKLPVDVLAVVATAVLIGSLLLAVLIYRRRLPEQDIPHNILVRLGRRTLRLPDLKLTL
IQLVITALDVAAAAMVLYLLLPHAPPLGAFILIYLLALAAGVLSHVPGGVGVFEAILLAAFANELGAAPLAAALLLYRLI
YVILPLLLACLTLLFTEAQRLLPTRQAMRVASGLAAPILALLVFLSGVVLLFSGATPEIDTRLENVGFMIPHRLIDASHF
GASLVGVLCLLLAQGLRRRLSAAWMLTSILLLVGAVLSILKGFDWEEASMLLLTACLLLTFRRSFYRPSRLLELPFSPVY
LIASICVVGASIWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSALGSAVLLVVVSLTWLLRTARPVIKLPDAEDLDKAA
EILKASKQPDGGLVLTGDKAILFHPAGNAFLMYSHRGRSLVALYDPIGPTQQRAELIWQFRDLCDVHHARPVFYQVRAEN
LPFYMDIGLTAIKLGEEARVDLHRFDIDAKGKEMKDLRYTWNRGGRDGLSLEIYEPGQAPIDELKVISDAWLTGKNVREK
GFSLGRFSTEYLKYFRIAIVHFQGKPVAFSNLLETTSPELASLDLMRSHPDAPKLTMEFMMVGLILHYKAQGYARFSLGM
VPLSGLQPRRGAPITQRLGSMIFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
>Mature_880_residues
MRDNMSDSNETIDAEQPVSPPRHNWRELLSKYRQPIGLAVMLLLFSLALIACRHMLVEMDWYALHDSLFAVPLPALGGAL
LAAIVGYIILMGYELSASRYANVDLPIKTLLLGGFTSFAIGNAVGLSMLSGGSVRYRLYSRHGVGAIEIARMTVFASLSL
GCALPPLAALATLSNLSGASLALKLPVDVLAVVATAVLIGSLLLAVLIYRRRLPEQDIPHNILVRLGRRTLRLPDLKLTL
IQLVITALDVAAAAMVLYLLLPHAPPLGAFILIYLLALAAGVLSHVPGGVGVFEAILLAAFANELGAAPLAAALLLYRLI
YVILPLLLACLTLLFTEAQRLLPTRQAMRVASGLAAPILALLVFLSGVVLLFSGATPEIDTRLENVGFMIPHRLIDASHF
GASLVGVLCLLLAQGLRRRLSAAWMLTSILLLVGAVLSILKGFDWEEASMLLLTACLLLTFRRSFYRPSRLLELPFSPVY
LIASICVVGASIWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSALGSAVLLVVVSLTWLLRTARPVIKLPDAEDLDKAA
EILKASKQPDGGLVLTGDKAILFHPAGNAFLMYSHRGRSLVALYDPIGPTQQRAELIWQFRDLCDVHHARPVFYQVRAEN
LPFYMDIGLTAIKLGEEARVDLHRFDIDAKGKEMKDLRYTWNRGGRDGLSLEIYEPGQAPIDELKVISDAWLTGKNVREK
GFSLGRFSTEYLKYFRIAIVHFQGKPVAFSNLLETTSPELASLDLMRSHPDAPKLTMEFMMVGLILHYKAQGYARFSLGM
VPLSGLQPRRGAPITQRLGSMIFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=285, Percent_Identity=29.1228070175439, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 96579; Mature: 96579

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDNMSDSNETIDAEQPVSPPRHNWRELLSKYRQPIGLAVMLLLFSLALIACRHMLVEMD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WYALHDSLFAVPLPALGGALLAAIVGYIILMGYELSASRYANVDLPIKTLLLGGFTSFAI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHCHHHHHH
GNAVGLSMLSGGSVRYRLYSRHGVGAIEIARMTVFASLSLGCALPPLAALATLSNLSGAS
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
LALKLPVDVLAVVATAVLIGSLLLAVLIYRRRLPEQDIPHNILVRLGRRTLRLPDLKLTL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHH
IQLVITALDVAAAAMVLYLLLPHAPPLGAFILIYLLALAAGVLSHVPGGVGVFEAILLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FANELGAAPLAAALLLYRLIYVILPLLLACLTLLFTEAQRLLPTRQAMRVASGLAAPILA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVFLSGVVLLFSGATPEIDTRLENVGFMIPHRLIDASHFGASLVGVLCLLLAQGLRRRL
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAWMLTSILLLVGAVLSILKGFDWEEASMLLLTACLLLTFRRSFYRPSRLLELPFSPVY
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHH
LIASICVVGASIWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSALGSAVLLVVVSLTWL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LRTARPVIKLPDAEDLDKAAEILKASKQPDGGLVLTGDKAILFHPAGNAFLMYSHRGRSL
HHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCEEEEEECCCCEE
VALYDPIGPTQQRAELIWQFRDLCDVHHARPVFYQVRAENLPFYMDIGLTAIKLGEEARV
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEECCCHHHC
DLHRFDIDAKGKEMKDLRYTWNRGGRDGLSLEIYEPGQAPIDELKVISDAWLTGKNVREK
CHHEECCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
GFSLGRFSTEYLKYFRIAIVHFQGKPVAFSNLLETTSPELASLDLMRSHPDAPKLTMEFM
CCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH
MVGLILHYKAQGYARFSLGMVPLSGLQPRRGAPITQRLGSMIFRRGEQLYNFQGLRRFKD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
KFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
HCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDNMSDSNETIDAEQPVSPPRHNWRELLSKYRQPIGLAVMLLLFSLALIACRHMLVEMD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WYALHDSLFAVPLPALGGALLAAIVGYIILMGYELSASRYANVDLPIKTLLLGGFTSFAI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHCHHHHHH
GNAVGLSMLSGGSVRYRLYSRHGVGAIEIARMTVFASLSLGCALPPLAALATLSNLSGAS
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
LALKLPVDVLAVVATAVLIGSLLLAVLIYRRRLPEQDIPHNILVRLGRRTLRLPDLKLTL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHH
IQLVITALDVAAAAMVLYLLLPHAPPLGAFILIYLLALAAGVLSHVPGGVGVFEAILLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FANELGAAPLAAALLLYRLIYVILPLLLACLTLLFTEAQRLLPTRQAMRVASGLAAPILA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVFLSGVVLLFSGATPEIDTRLENVGFMIPHRLIDASHFGASLVGVLCLLLAQGLRRRL
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAWMLTSILLLVGAVLSILKGFDWEEASMLLLTACLLLTFRRSFYRPSRLLELPFSPVY
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHH
LIASICVVGASIWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSALGSAVLLVVVSLTWL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LRTARPVIKLPDAEDLDKAAEILKASKQPDGGLVLTGDKAILFHPAGNAFLMYSHRGRSL
HHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCEEEEEECCCCEE
VALYDPIGPTQQRAELIWQFRDLCDVHHARPVFYQVRAENLPFYMDIGLTAIKLGEEARV
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEECCCHHHC
DLHRFDIDAKGKEMKDLRYTWNRGGRDGLSLEIYEPGQAPIDELKVISDAWLTGKNVREK
CHHEECCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
GFSLGRFSTEYLKYFRIAIVHFQGKPVAFSNLLETTSPELASLDLMRSHPDAPKLTMEFM
CCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH
MVGLILHYKAQGYARFSLGMVPLSGLQPRRGAPITQRLGSMIFRRGEQLYNFQGLRRFKD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
KFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
HCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA