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The map label for this gene is yeiG [H]

Identifier: 66044616

GI number: 66044616

Start: 1551681

End: 1552526

Strand: Direct

Name: yeiG [H]

Synonym: Psyr_1368

Alternate gene names: 66044616

Gene position: 1551681-1552526 (Clockwise)

Preceding gene: 66044615

Following gene: 66044617

Centisome position: 25.46

GC content: 60.05

Gene sequence:

>846_bases
ATGCCTTTGGAAAATATTTCCTGTCAAAAGAGTTTCGGCGGCTGGCACAAGCGCTACAAGCACCACTCCCAGGTGCTGGG
CTGCGACATGGTGTTTGCCGTCTATCTGCCACCGCAGGCGGAGCAGGGCGGCAAGCTGCCGGTGTTGTACTGGCTGTCCG
GCCTGACCTGTACGGATGAAAATTTCATGCAGAAAGCCGCCGCCCATCGACTGGCGGCCGAGTTGGGCATCATCATCGTG
GCGCCTGATACCAGTCCGCGTGGTGCCGACGTGGCAGATGACCCTGACGGCGCCTGGGACTTCGGTCAAGGCGCGGGCTT
CTACCTCAACGCTACCGAGCAGCCTTATGCACGGCATTACCAAATGCATGATTACGTGGTCAAGGAGCTGCCGGCGCTGA
TCGAGGGGCATTTTCCGGCGTCACAGGTGCGCAGTATCAGCGGGCACTCGATGGGCGGTCACGGGGCGCTGGTCTGCGCA
TTGCGTAATCCGGGTCGCTATCGGTCGGTGTCGGCGTTCTCGCCGATCAGTAATCCGATCGATTGCCCATGGGGGCAAAA
GGCATTCTCGCGTTATCTGGGCGAAGACCGTTCCCGCTGGCGCGAATGGGATGCCAGCGTGTTGATTGCGCAGGCGTCCG
AAAAGCTGCCGACGCTGGTCGATCAGGGCGATCGTGACGATTTTCTGGTCAATCAGCTCAAGCCTGAGGCGCTGGTTCAG
GCGGCCAAGGCTGCGGACTATCCGCTGACCCTGCGCATGCAGCCAGGCTACGACCACAGCTATTTCTTCATCGCCAGCTT
CATTGAGGACCATCTCAGGCATCACGCTGCAGCCTTGAACAGCTAA

Upstream 100 bases:

>100_bases
TTAAGGAGCAGCGGCAAGCTGTCAGCTCCAAGCGGCAAGCACGAAGGTCTCTTACCTGCTTGTAGCTTGCGGCTTATAGC
TTGCAGCTGGAGGACATCAC

Downstream 100 bases:

>100_bases
CGCGCGCCAAAGCAGGTAGAATCACGCCCTGACTTTTTTCAGGGCGTTTTTTTATGCGTATTGGCCATGGCTATGATGTG
CACCGTTTTGCTGAAGGCGA

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPLENISCQKSFGGWHKRYKHHSQVLGCDMVFAVYLPPQAEQGGKLPVLYWLSGLTCTDENFMQKAAAHRLAAELGIIIV
APDTSPRGADVADDPDGAWDFGQGAGFYLNATEQPYARHYQMHDYVVKELPALIEGHFPASQVRSISGHSMGGHGALVCA
LRNPGRYRSVSAFSPISNPIDCPWGQKAFSRYLGEDRSRWREWDASVLIAQASEKLPTLVDQGDRDDFLVNQLKPEALVQ
AAKAADYPLTLRMQPGYDHSYFFIASFIEDHLRHHAAALNS

Sequences:

>Translated_281_residues
MPLENISCQKSFGGWHKRYKHHSQVLGCDMVFAVYLPPQAEQGGKLPVLYWLSGLTCTDENFMQKAAAHRLAAELGIIIV
APDTSPRGADVADDPDGAWDFGQGAGFYLNATEQPYARHYQMHDYVVKELPALIEGHFPASQVRSISGHSMGGHGALVCA
LRNPGRYRSVSAFSPISNPIDCPWGQKAFSRYLGEDRSRWREWDASVLIAQASEKLPTLVDQGDRDDFLVNQLKPEALVQ
AAKAADYPLTLRMQPGYDHSYFFIASFIEDHLRHHAAALNS
>Mature_280_residues
PLENISCQKSFGGWHKRYKHHSQVLGCDMVFAVYLPPQAEQGGKLPVLYWLSGLTCTDENFMQKAAAHRLAAELGIIIVA
PDTSPRGADVADDPDGAWDFGQGAGFYLNATEQPYARHYQMHDYVVKELPALIEGHFPASQVRSISGHSMGGHGALVCAL
RNPGRYRSVSAFSPISNPIDCPWGQKAFSRYLGEDRSRWREWDASVLIAQASEKLPTLVDQGDRDDFLVNQLKPEALVQA
AKAADYPLTLRMQPGYDHSYFFIASFIEDHLRHHAAALNS

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=284, Percent_Identity=54.9295774647887, Blast_Score=332, Evalue=3e-91,
Organism=Escherichia coli, GI1788477, Length=279, Percent_Identity=58.7813620071685, Blast_Score=337, Evalue=5e-94,
Organism=Escherichia coli, GI1786551, Length=278, Percent_Identity=53.2374100719424, Blast_Score=303, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=50.179211469534, Blast_Score=268, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6322393, Length=286, Percent_Identity=43.7062937062937, Blast_Score=237, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45551932, Length=285, Percent_Identity=50.5263157894737, Blast_Score=294, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24648347, Length=285, Percent_Identity=50.5263157894737, Blast_Score=294, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31213; Mature: 31082

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLENISCQKSFGGWHKRYKHHSQVLGCDMVFAVYLPPQAEQGGKLPVLYWLSGLTCTDE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCCCCCH
NFMQKAAAHRLAAELGIIIVAPDTSPRGADVADDPDGAWDFGQGAGFYLNATEQPYARHY
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
QMHDYVVKELPALIEGHFPASQVRSISGHSMGGHGALVCALRNPGRYRSVSAFSPISNPI
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
DCPWGQKAFSRYLGEDRSRWREWDASVLIAQASEKLPTLVDQGDRDDFLVNQLKPEALVQ
CCCCCHHHHHHHHCHHHHHHHHHCHHEEEEHHHHHCCHHHCCCCCCCHHHHHCCHHHHHH
AAKAADYPLTLRMQPGYDHSYFFIASFIEDHLRHHAAALNS
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLENISCQKSFGGWHKRYKHHSQVLGCDMVFAVYLPPQAEQGGKLPVLYWLSGLTCTDE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCCCCCH
NFMQKAAAHRLAAELGIIIVAPDTSPRGADVADDPDGAWDFGQGAGFYLNATEQPYARHY
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
QMHDYVVKELPALIEGHFPASQVRSISGHSMGGHGALVCALRNPGRYRSVSAFSPISNPI
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
DCPWGQKAFSRYLGEDRSRWREWDASVLIAQASEKLPTLVDQGDRDDFLVNQLKPEALVQ
CCCCCHHHHHHHHCHHHHHHHHHCHHEEEEHHHHHCCHHHCCCCCCCHHHHHCCHHHHHH
AAKAADYPLTLRMQPGYDHSYFFIASFIEDHLRHHAAALNS
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA