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The map label for this gene is csdA [H]

Identifier: 66044583

GI number: 66044583

Start: 1513884

End: 1515125

Strand: Reverse

Name: csdA [H]

Synonym: Psyr_1335

Alternate gene names: 66044583

Gene position: 1515125-1513884 (Counterclockwise)

Preceding gene: 66044584

Following gene: 66044582

Centisome position: 24.86

GC content: 62.8

Gene sequence:

>1242_bases
ATGGCTTTGAACCCGCCTCCACACGCTGGACGAACAATGCCCCTCTTCTCTCCCTGGCGTGGCGACTTCCCCGCCATCGC
CGCCCTGCAACGGCAAGGCCAGACTTATCTGGACAACGCCGCCACGACGCAAAAGCCCCAGGCGCTGATCGACGCCCTGA
CTCATTACTATGCCAACGGTGCCGCCAATGTGCATCGTGCCCAGCATCTGCCCGGCGCACACGCCACTCAAGCGTTCGAG
GCCAGCCGTGGCAAGGCCGCCCGCTGGCTGAATGCCGGCGAGAACGGCCAGATCATCTTCACTCACGGCGCGACGTCTGC
GCTGAACCTGCTGGCCTACGGGCTGGAACATGAATTCGCGGCGGGCGACGAAATCGCCATCAGCGCGCTGGAACATCACG
CCAATCTGCTGCCATGGCAGCAACTGGCTCAGCGTCGCGGCCTGAAACTGGTGGTTCTGCCGCTGGATATCGATGGCGTG
ATCGACTGCGACGCGGCAGCCAACCTGATCGGACCGCGCACACGTCTGCTCGCCGTCACCCAGCTCTCCAACGTGCTCGG
CACCTGGCAACCGCTCGCTCGTCTTATCGCACTGGCCAAGACCCAAGGCGCCATTACCGTCGTGGACGGCTCACAGGGCG
TGGTGCACGGACGCCACGATGTGCAGGCGCTGGGCTGCGATTTTTATGTGTTTTCCAGCCACAAACTGTATGGCCCGGAA
GGACTCGGCGTGCTTTACGGGTGCAACGAGGCGCTGCCCAGCCTCGCGCACTGGCAGTTCGGCGGCGAGATGGTGCTGAC
AGCCGATTATCAGCACGCGAAATTTCGTCCGGCACCCCTGGGTTTCGAGGCCGGCACCCCGCCCATCGCCAGTGTGATCG
GTCTGGGCGCTACGCTGGCCTATCTGGACAGCCTCGATCATCAGGCGGTCGCAGAACATGAAGCCAGACTGCACCGTCGC
CTGCTTGAGGGCCTGCAACAGCGTAATGGCATCCAGGTTCTGGGCTCGCCGGATCTGGCACTGGTCAGCTTCGTCGTCGA
CGATGTTCACAATGCTGATGTGGCTCACCTGCTGACCGAACAGGGCATTGCCGTACGTGCCGGTCATCATTGCGCGATGC
CGCTGTTCAAGACCCTTGGCCTGCCCGGCGCGATTCGCGTGTCACTGGCGCTGTACAACGATTCGGACGATCTGCTGCAG
TTCTTCAGCGCACTGGATCAAGCACTGGAGCTGCTTCGATGA

Upstream 100 bases:

>100_bases
CTCAGACCGGCGCGGTGGAATGCAAAACCCACAAGTCGGCCGTCGAGCTGAACGAAGCACTGCACGCTCATAACTGATGC
TGTGTGCGGGTTCAAGGCTG

Downstream 100 bases:

>100_bases
GTCTGCCGCCATTGGCGCAAACTGCGCTCGACAGTTTTTCCCGGCCGCAAGGCTGGGAACAGCGCGCACGCCTGCTGATG
CAATGGGGTGATCAACTCGC

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MALNPPPHAGRTMPLFSPWRGDFPAIAALQRQGQTYLDNAATTQKPQALIDALTHYYANGAANVHRAQHLPGAHATQAFE
ASRGKAARWLNAGENGQIIFTHGATSALNLLAYGLEHEFAAGDEIAISALEHHANLLPWQQLAQRRGLKLVVLPLDIDGV
IDCDAAANLIGPRTRLLAVTQLSNVLGTWQPLARLIALAKTQGAITVVDGSQGVVHGRHDVQALGCDFYVFSSHKLYGPE
GLGVLYGCNEALPSLAHWQFGGEMVLTADYQHAKFRPAPLGFEAGTPPIASVIGLGATLAYLDSLDHQAVAEHEARLHRR
LLEGLQQRNGIQVLGSPDLALVSFVVDDVHNADVAHLLTEQGIAVRAGHHCAMPLFKTLGLPGAIRVSLALYNDSDDLLQ
FFSALDQALELLR

Sequences:

>Translated_413_residues
MALNPPPHAGRTMPLFSPWRGDFPAIAALQRQGQTYLDNAATTQKPQALIDALTHYYANGAANVHRAQHLPGAHATQAFE
ASRGKAARWLNAGENGQIIFTHGATSALNLLAYGLEHEFAAGDEIAISALEHHANLLPWQQLAQRRGLKLVVLPLDIDGV
IDCDAAANLIGPRTRLLAVTQLSNVLGTWQPLARLIALAKTQGAITVVDGSQGVVHGRHDVQALGCDFYVFSSHKLYGPE
GLGVLYGCNEALPSLAHWQFGGEMVLTADYQHAKFRPAPLGFEAGTPPIASVIGLGATLAYLDSLDHQAVAEHEARLHRR
LLEGLQQRNGIQVLGSPDLALVSFVVDDVHNADVAHLLTEQGIAVRAGHHCAMPLFKTLGLPGAIRVSLALYNDSDDLLQ
FFSALDQALELLR
>Mature_412_residues
ALNPPPHAGRTMPLFSPWRGDFPAIAALQRQGQTYLDNAATTQKPQALIDALTHYYANGAANVHRAQHLPGAHATQAFEA
SRGKAARWLNAGENGQIIFTHGATSALNLLAYGLEHEFAAGDEIAISALEHHANLLPWQQLAQRRGLKLVVLPLDIDGVI
DCDAAANLIGPRTRLLAVTQLSNVLGTWQPLARLIALAKTQGAITVVDGSQGVVHGRHDVQALGCDFYVFSSHKLYGPEG
LGVLYGCNEALPSLAHWQFGGEMVLTADYQHAKFRPAPLGFEAGTPPIASVIGLGATLAYLDSLDHQAVAEHEARLHRRL
LEGLQQRNGIQVLGSPDLALVSFVVDDVHNADVAHLLTEQGIAVRAGHHCAMPLFKTLGLPGAIRVSLALYNDSDDLLQF
FSALDQALELLR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=293, Percent_Identity=26.962457337884, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI156713448, Length=354, Percent_Identity=26.8361581920904, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789175, Length=403, Percent_Identity=43.1761786600496, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1787970, Length=397, Percent_Identity=41.8136020151133, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI48994898, Length=402, Percent_Identity=26.3681592039801, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=344, Percent_Identity=25.8720930232558, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319831, Length=303, Percent_Identity=27.7227722772277, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI20129463, Length=262, Percent_Identity=28.6259541984733, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44357; Mature: 44226

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNPPPHAGRTMPLFSPWRGDFPAIAALQRQGQTYLDNAATTQKPQALIDALTHYYANG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCC
AANVHRAQHLPGAHATQAFEASRGKAARWLNAGENGQIIFTHGATSALNLLAYGLEHEFA
CCHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCCCC
AGDEIAISALEHHANLLPWQQLAQRRGLKLVVLPLDIDGVIDCDAAANLIGPRTRLLAVT
CCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCEEECCHHHHHCCCHHHHHHHH
QLSNVLGTWQPLARLIALAKTQGAITVVDGSQGVVHGRHDVQALGCDFYVFSSHKLYGPE
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCEEECCEEEEEECCEEECCC
GLGVLYGCNEALPSLAHWQFGGEMVLTADYQHAKFRPAPLGFEAGTPPIASVIGLGATLA
CCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLDSLDHQAVAEHEARLHRRLLEGLQQRNGIQVLGSPDLALVSFVVDDVHNADVAHLLTE
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHH
QGIAVRAGHHCAMPLFKTLGLPGAIRVSLALYNDSDDLLQFFSALDQALELLR
CCCEEECCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ALNPPPHAGRTMPLFSPWRGDFPAIAALQRQGQTYLDNAATTQKPQALIDALTHYYANG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCC
AANVHRAQHLPGAHATQAFEASRGKAARWLNAGENGQIIFTHGATSALNLLAYGLEHEFA
CCHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCCCC
AGDEIAISALEHHANLLPWQQLAQRRGLKLVVLPLDIDGVIDCDAAANLIGPRTRLLAVT
CCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCEEECCHHHHHCCCHHHHHHHH
QLSNVLGTWQPLARLIALAKTQGAITVVDGSQGVVHGRHDVQALGCDFYVFSSHKLYGPE
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCEEECCEEEEEECCEEECCC
GLGVLYGCNEALPSLAHWQFGGEMVLTADYQHAKFRPAPLGFEAGTPPIASVIGLGATLA
CCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLDSLDHQAVAEHEARLHRRLLEGLQQRNGIQVLGSPDLALVSFVVDDVHNADVAHLLTE
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHH
QGIAVRAGHHCAMPLFKTLGLPGAIRVSLALYNDSDDLLQFFSALDQALELLR
CCCEEECCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]