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The map label for this gene is xseA

Identifier: 66044507

GI number: 66044507

Start: 1415962

End: 1417353

Strand: Reverse

Name: xseA

Synonym: Psyr_1259

Alternate gene names: 66044507

Gene position: 1417353-1415962 (Counterclockwise)

Preceding gene: 66044516

Following gene: 66044506

Centisome position: 23.26

GC content: 64.8

Gene sequence:

>1392_bases
ATGATGCCCGACATGATCAAAGACCCTTTCGCAAGACTCGGCCTCGACCGGGAAGTCCTTACTGTCAGCCAGCTCAACGG
CCGCGCCCGCGTGCTGCTGGAAGACGTGTTCAGCAGCATCTGGGTCGAGGGCGAGATCTCCAACCTCTCGCGCCCGGCCT
CGGGCCATGTGTACTTCACGCTGAAGGACTCTGGCGCGCAGGTCCGCTGCGCGTTGTTCCGGCAGAGCGCAGCGCGGGTG
CGTCAGGCGCTCAAGGACGGCTTGCAGGTCAAGGTGCGCGGCAAGGTTTCGCTGTTTGAGGGCCGCGGCGACTATCAGCT
GATTCTCGATACCGTGGAACCTGCCGGTGACGGTGCATTGCGCCTGGCGTTCGATGCGCTGAAAGCCAAGCTCAGCGACG
AAGGCCTGTTCAGCGCCGAGCGCAAGGTCGCTCTGCCGCTGCACCCGCAACGTATCGGGATCATCAGCTCACCGACCGGT
GCGGTGATCCGCGACATCATCAGCGTGTTCCGTCGTCGCGCGCCGCGGGTCGAGCTGACCTTGATTCCCACCGCCGTTCA
GGGCCGCGAGGCGATCAACCAGATTGTCCGCGCACTGAAGCTGGCCGACAGCAGAGGCTTCGATGCGCTGATCCTGGCCC
GTGGCGGCGGCTCGCTGGAGGACCTGTGGTGCTTCAACGAAGAAGCCGTCGCCCGCGCCATCGACGCGTGCGTGACGCCG
ATTGTCAGCGCTGTCGGGCATGAAACCGATGTGTCCATCAGCGACTTTGTCGCCGACGTGCGCGCACCGACGCCCTCCGC
TGCCGCCGAACTGCTCGCCCCGGATTCCAGCGACCTGCATCGACGCGTCGACAACCTGCACCGGCGACTGGTCAGCCGCA
TGCAGGACCGACTGATGCGCGAGCGGCTGCGTCTCGAGGGTATTTCCCGGCGTCTGCGCCACCCTGGCGAGCGCTTGCGT
CAGCAGTCGCAACGCCTGGATGACCTGGACATGCGCCTGCGCCGCGCCCTTGAACAGACCATGCATCAACGTCAGCTGCG
TCTGGCGCACATGCAAAGCCGCCTTGCTGCCCAGCATCCAGGCCGGACCCTGGCCTTTTTGCGCCAGCGTCTGGATGCCT
TGGCCGAGCGTCTGCCGAGAGCCATTCGCGAACAGATCAAGGCGCGCAAGCTTCAATTACAAAGTCAGGTGCAGACCCTC
AACGTGGTCAGCCCGCTCGCCACACTGGGACGCGGTTACAGCATTCTGCTCGACGAGCGCGGCCACGCGATTCGTAACGC
TGCACAGACGCAGACCGGCCAACGGCTTACCGCCAGGCTCGGCGAAGGCGAACTGCACGTGCGTGTCGAAGACAATCACC
TCACACCCGTGACCCTCTCCCTTCTGGACTGA

Upstream 100 bases:

>100_bases
CTGTTCGAGGCCGCAGCTTAATGGGCTGGCCATTCAGGTCAAGAAGCAATCCTGCCTTTACCGACGAGACAGACCTGTGC
GCCAGACCGGCATTGCCATT

Downstream 100 bases:

>100_bases
CTGCCTGATGCTACGTTTTATCGCCCCGCTGTTCGCCCTGCTGCTCTGTCTGCCCGCCCACGCCGACAGCTTTATTACCC
GCGCACTCGACAAACCGGTG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MMPDMIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSSIWVEGEISNLSRPASGHVYFTLKDSGAQVRCALFRQSAARV
RQALKDGLQVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKAKLSDEGLFSAERKVALPLHPQRIGIISSPTG
AVIRDIISVFRRRAPRVELTLIPTAVQGREAINQIVRALKLADSRGFDALILARGGGSLEDLWCFNEEAVARAIDACVTP
IVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLHRRVDNLHRRLVSRMQDRLMRERLRLEGISRRLRHPGERLR
QQSQRLDDLDMRLRRALEQTMHQRQLRLAHMQSRLAAQHPGRTLAFLRQRLDALAERLPRAIREQIKARKLQLQSQVQTL
NVVSPLATLGRGYSILLDERGHAIRNAAQTQTGQRLTARLGEGELHVRVEDNHLTPVTLSLLD

Sequences:

>Translated_463_residues
MMPDMIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSSIWVEGEISNLSRPASGHVYFTLKDSGAQVRCALFRQSAARV
RQALKDGLQVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKAKLSDEGLFSAERKVALPLHPQRIGIISSPTG
AVIRDIISVFRRRAPRVELTLIPTAVQGREAINQIVRALKLADSRGFDALILARGGGSLEDLWCFNEEAVARAIDACVTP
IVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLHRRVDNLHRRLVSRMQDRLMRERLRLEGISRRLRHPGERLR
QQSQRLDDLDMRLRRALEQTMHQRQLRLAHMQSRLAAQHPGRTLAFLRQRLDALAERLPRAIREQIKARKLQLQSQVQTL
NVVSPLATLGRGYSILLDERGHAIRNAAQTQTGQRLTARLGEGELHVRVEDNHLTPVTLSLLD
>Mature_463_residues
MMPDMIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSSIWVEGEISNLSRPASGHVYFTLKDSGAQVRCALFRQSAARV
RQALKDGLQVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKAKLSDEGLFSAERKVALPLHPQRIGIISSPTG
AVIRDIISVFRRRAPRVELTLIPTAVQGREAINQIVRALKLADSRGFDALILARGGGSLEDLWCFNEEAVARAIDACVTP
IVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLHRRVDNLHRRLVSRMQDRLMRERLRLEGISRRLRHPGERLR
QQSQRLDDLDMRLRRALEQTMHQRQLRLAHMQSRLAAQHPGRTLAFLRQRLDALAERLPRAIREQIKARKLQLQSQVQTL
NVVSPLATLGRGYSILLDERGHAIRNAAQTQTGQRLTARLGEGELHVRVEDNHLTPVTLSLLD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=445, Percent_Identity=44.4943820224719, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_PSEU2 (Q4ZX12)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_234348.1
- STRING:   Q4ZX12
- GeneID:   3366754
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_1259
- NMPDR:   fig|205918.4.peg.1573
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   SSQIRCA
- ProtClustDB:   PRK00286
- BioCyc:   PSYR205918:PSYR_1259-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51692; Mature: 51692

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPDMIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSSIWVEGEISNLSRPASGHVYFT
CCCCHHCCHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCHHCCCCCCCCEEEEE
LKDSGAQVRCALFRQSAARVRQALKDGLQVKVRGKVSLFEGRGDYQLILDTVEPAGDGAL
EECCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCCHH
RLAFDALKAKLSDEGLFSAERKVALPLHPQRIGIISSPTGAVIRDIISVFRRRAPRVELT
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEE
LIPTAVQGREAINQIVRALKLADSRGFDALILARGGGSLEDLWCFNEEAVARAIDACVTP
EECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHH
IVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLHRRVDNLHRRLVSRMQDRLMR
HHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERLRLEGISRRLRHPGERLRQQSQRLDDLDMRLRRALEQTMHQRQLRLAHMQSRLAAQHP
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRTLAFLRQRLDALAERLPRAIREQIKARKLQLQSQVQTLNVVSPLATLGRGYSILLDER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GHAIRNAAQTQTGQRLTARLGEGELHVRVEDNHLTPVTLSLLD
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MMPDMIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSSIWVEGEISNLSRPASGHVYFT
CCCCHHCCHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCHHCCCCCCCCEEEEE
LKDSGAQVRCALFRQSAARVRQALKDGLQVKVRGKVSLFEGRGDYQLILDTVEPAGDGAL
EECCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCCHH
RLAFDALKAKLSDEGLFSAERKVALPLHPQRIGIISSPTGAVIRDIISVFRRRAPRVELT
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEE
LIPTAVQGREAINQIVRALKLADSRGFDALILARGGGSLEDLWCFNEEAVARAIDACVTP
EECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHH
IVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSDLHRRVDNLHRRLVSRMQDRLMR
HHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERLRLEGISRRLRHPGERLRQQSQRLDDLDMRLRRALEQTMHQRQLRLAHMQSRLAAQHP
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRTLAFLRQRLDALAERLPRAIREQIKARKLQLQSQVQTLNVVSPLATLGRGYSILLDER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GHAIRNAAQTQTGQRLTARLGEGELHVRVEDNHLTPVTLSLLD
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA