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The map label for this gene is HrcU [H]

Identifier: 66044456

GI number: 66044456

Start: 1364133

End: 1365212

Strand: Reverse

Name: HrcU [H]

Synonym: Psyr_1205

Alternate gene names: 66044456

Gene position: 1365212-1364133 (Counterclockwise)

Preceding gene: 66044457

Following gene: 66044455

Centisome position: 22.4

GC content: 57.31

Gene sequence:

>1080_bases
GTGAGCGAAAAAACCGAAAAGGCCACGCCCAAGCAACTGCGTGACGCGCGGGAAAAGGGTCAGGTCGGGCAGAGTCAGGA
CCTCGGCAAACTGCTGGTGTTGATGGCCGTCAGTGAAATTACCCTGGCCCTGGCTGATGAAAGCGTCAACCGACTGGAGG
CGCTGTTGTCGCTGTCCTTTCAAGGCATCGACCGCAGCTTTGCCGCGTCGGTCGAGCTGATCGCCAGCGAAGGACTCTCG
GTACTGCTCAGCTTTACCTTGTGCAGCGTCGGTATAGCGATGCTGATGCGTCTGATCAGCAGCTGGATGCAGATCGGTTT
TCTGTTCGCGCCCAAGGCGCTGAAAATCGATCCCAACAAGATCAACCCGTTCTCCCACGCCAAACAGATGTTTTCCGGGC
AAAACCTGCTCAACCTGCTGCTCAGTGTGCTCAAGGCCATTGCCATCGGCGCGACGCTGTATGTGCAAGTCAAACCTGTG
CTGGGCACCCTGGTGTTGCTGGCCAACAGCGATCTGACGACCTACTGGCATGCCCTGGTCGAGCTGTTCAGGCATATTTT
GCGAGTGATATTGGGGCTGCTGCTGGCGATCGCGATGATCGACTTCGCCATGCAGAAATACTTCCATGCGAAAAAACTGC
GCATGAGCCACGAGGACATCAAGAAAGAGTACAAGCAATCGGAAGGCGACCCCCACGTCAAAGGCCATCGTCGGCAACTT
GCCCAGGAGATCCTCAATCAGGAGCCCAGTGCTGCGCCCAAGCCTGTGGAAGACGCCGACATGCTGCTGGTCAACCCGAC
GCACTACGCGGTGGCCCTGTATTACCGACCAGGCGAAACGCCTCTGCCGCTGATTCATTGCAAAGGTGAAGACGAGGAAG
CCCTGGCATTGATTGCCCGCGCCAAAAAAGCCGGCATCCCGGTGGTGCAGAGCATCTGGCTGACCAGGACGCTGTACCGC
TCCAAGGTCGGAAAATATATCCCCCGGCCCACCCTGCAGGCTGTCGGTCACATCTACAAAGTGGTTCGGCAACTGGACGA
AGTCACCGATGAGGTGATTCAGGTTGAAGTCGAGCTGTGA

Upstream 100 bases:

>100_bases
TTCTGCTGATCTATCTGCCGACGCTGCTGGAACTGGGCACCGGTCAATTGTTGAAGCTGGTTGATCTGAAGTCGCTACTG
ACGCTTCTGGTGCAAGTGCC

Downstream 100 bases:

>100_bases
TGGCTTATTGTCCACTGACGAACCAAAATGCAGCTGTACTTGTTTACGGCATGTTCGAGCATCTCTGCCATGCCACTGTC
CATTAAACTATCCAGATCCA

Product: type III secretion protein HrcU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSEKTEKATPKQLRDAREKGQVGQSQDLGKLLVLMAVSEITLALADESVNRLEALLSLSFQGIDRSFAASVELIASEGLS
VLLSFTLCSVGIAMLMRLISSWMQIGFLFAPKALKIDPNKINPFSHAKQMFSGQNLLNLLLSVLKAIAIGATLYVQVKPV
LGTLVLLANSDLTTYWHALVELFRHILRVILGLLLAIAMIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQL
AQEILNQEPSAAPKPVEDADMLLVNPTHYAVALYYRPGETPLPLIHCKGEDEEALALIARAKKAGIPVVQSIWLTRTLYR
SKVGKYIPRPTLQAVGHIYKVVRQLDEVTDEVIQVEVEL

Sequences:

>Translated_359_residues
MSEKTEKATPKQLRDAREKGQVGQSQDLGKLLVLMAVSEITLALADESVNRLEALLSLSFQGIDRSFAASVELIASEGLS
VLLSFTLCSVGIAMLMRLISSWMQIGFLFAPKALKIDPNKINPFSHAKQMFSGQNLLNLLLSVLKAIAIGATLYVQVKPV
LGTLVLLANSDLTTYWHALVELFRHILRVILGLLLAIAMIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQL
AQEILNQEPSAAPKPVEDADMLLVNPTHYAVALYYRPGETPLPLIHCKGEDEEALALIARAKKAGIPVVQSIWLTRTLYR
SKVGKYIPRPTLQAVGHIYKVVRQLDEVTDEVIQVEVEL
>Mature_358_residues
SEKTEKATPKQLRDAREKGQVGQSQDLGKLLVLMAVSEITLALADESVNRLEALLSLSFQGIDRSFAASVELIASEGLSV
LLSFTLCSVGIAMLMRLISSWMQIGFLFAPKALKIDPNKINPFSHAKQMFSGQNLLNLLLSVLKAIAIGATLYVQVKPVL
GTLVLLANSDLTTYWHALVELFRHILRVILGLLLAIAMIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQLA
QEILNQEPSAAPKPVEDADMLLVNPTHYAVALYYRPGETPLPLIHCKGEDEEALALIARAKKAGIPVVQSIWLTRTLYRS
KVGKYIPRPTLQAVGHIYKVVRQLDEVTDEVIQVEVEL

Specific function: Component of the yop secretion machinery [H]

COG id: COG4792

COG function: function code U; Type III secretory pathway, component EscU

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=352, Percent_Identity=32.3863636363636, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006135
- InterPro:   IPR006307 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 39979; Mature: 39847

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTEKATPKQLRDAREKGQVGQSQDLGKLLVLMAVSEITLALADESVNRLEALLSLSF
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGIDRSFAASVELIASEGLSVLLSFTLCSVGIAMLMRLISSWMQIGFLFAPKALKIDPNK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
INPFSHAKQMFSGQNLLNLLLSVLKAIAIGATLYVQVKPVLGTLVLLANSDLTTYWHALV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHEEEEEHHHHHHHHHHCCCCHHHHHHHHH
ELFRHILRVILGLLLAIAMIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHH
AQEILNQEPSAAPKPVEDADMLLVNPTHYAVALYYRPGETPLPLIHCKGEDEEALALIAR
HHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHH
AKKAGIPVVQSIWLTRTLYRSKVGKYIPRPTLQAVGHIYKVVRQLDEVTDEVIQVEVEL
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SEKTEKATPKQLRDAREKGQVGQSQDLGKLLVLMAVSEITLALADESVNRLEALLSLSF
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGIDRSFAASVELIASEGLSVLLSFTLCSVGIAMLMRLISSWMQIGFLFAPKALKIDPNK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
INPFSHAKQMFSGQNLLNLLLSVLKAIAIGATLYVQVKPVLGTLVLLANSDLTTYWHALV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHEEEEEHHHHHHHHHHCCCCHHHHHHHHH
ELFRHILRVILGLLLAIAMIDFAMQKYFHAKKLRMSHEDIKKEYKQSEGDPHVKGHRRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHH
AQEILNQEPSAAPKPVEDADMLLVNPTHYAVALYYRPGETPLPLIHCKGEDEEALALIAR
HHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHH
AKKAGIPVVQSIWLTRTLYRSKVGKYIPRPTLQAVGHIYKVVRQLDEVTDEVIQVEVEL
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9746557; 9748454; 11586360 [H]