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The map label for this gene is pheC [H]

Identifier: 66044402

GI number: 66044402

Start: 1303150

End: 1303941

Strand: Reverse

Name: pheC [H]

Synonym: Psyr_1151

Alternate gene names: 66044402

Gene position: 1303941-1303150 (Counterclockwise)

Preceding gene: 66044406

Following gene: 66044401

Centisome position: 21.4

GC content: 58.21

Gene sequence:

>792_bases
ATGATGAATCTTAAATACAGCGCACTGACCGCCTTGTTGCTGGGCATCACAGGCATGGCTCAGGCTCAGGACTACACCTC
GCATCTGGACAAGGTGCTGCAGGCCGGCCAGCTGGCTGTGTGCACCACTGGCGACTACAAGCCCTACTCCCTGCTGCGCG
AAGACGGCGAATACGAAGGCATTGATATCACCATGGCCCGTTCACTGGCCAAGAGCCTGGGGGTGAACGTGCAGTGGGTG
CCCACGACGTGGAAAAACCTGATGCCGGACATGGTGGCCGGTAAATGCGACATCGGTATGGGTGGCATCTCGGTGAGCCT
GGAACGCCAGAAAAAAGCGTTTTTCAGCAACACGCTGGACGTCGATGGCAAAATCCCGCTGGTCCGCTGCGCCGATCAGG
CCCTGTATCAGACTGTCGAGCAGATCAACCAGCCCTCTGTGCGTTTGATCGAACCTGCCGGTGGCACCAATGAAGCCTTC
GCTCGCGCTCATCTGCCAAAGGCGTCGCTGGCCTTTCATGACAACAAGACCATCTTTCAGGAGCTGCTGGACAAGAAAGC
TGACGTGATGATCACCGATGCTTCCGAAGCGCTCTACCAGCAGAAACGCATGCCGGGCCTGTGTGCCGTCAACCCGACCC
GCTACATGCAATACGGCGAAAAAGCCTATTTGTTGCCACGCGACGATGTCGCCTGGAAAGCCTATGTGGATCAGTGGCTG
CACCTGAGCAAGGCCACTGGCGAGTATCAGCAGGCGCTGAGCGAGTGGCTGGCAGTACCCGCCACCCCTTGA

Upstream 100 bases:

>100_bases
TCAACGGCATGTTTTGATTACAGCTTCACATCGGCCTGACAAATGAAGCAATCTGTCGACTTCAATAAAACCGACTGCAC
CGCTGCGAGTATCCAGACTC

Downstream 100 bases:

>100_bases
TAGACATTATTTAGCCATCACCTAAAGTCAGGATTTTCTACGCCGATACTTATTTGTTCCTCGGTATTACTGACGAGGCC
ATCAATAGGCTTTCACAGGG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MMNLKYSALTALLLGITGMAQAQDYTSHLDKVLQAGQLAVCTTGDYKPYSLLREDGEYEGIDITMARSLAKSLGVNVQWV
PTTWKNLMPDMVAGKCDIGMGGISVSLERQKKAFFSNTLDVDGKIPLVRCADQALYQTVEQINQPSVRLIEPAGGTNEAF
ARAHLPKASLAFHDNKTIFQELLDKKADVMITDASEALYQQKRMPGLCAVNPTRYMQYGEKAYLLPRDDVAWKAYVDQWL
HLSKATGEYQQALSEWLAVPATP

Sequences:

>Translated_263_residues
MMNLKYSALTALLLGITGMAQAQDYTSHLDKVLQAGQLAVCTTGDYKPYSLLREDGEYEGIDITMARSLAKSLGVNVQWV
PTTWKNLMPDMVAGKCDIGMGGISVSLERQKKAFFSNTLDVDGKIPLVRCADQALYQTVEQINQPSVRLIEPAGGTNEAF
ARAHLPKASLAFHDNKTIFQELLDKKADVMITDASEALYQQKRMPGLCAVNPTRYMQYGEKAYLLPRDDVAWKAYVDQWL
HLSKATGEYQQALSEWLAVPATP
>Mature_263_residues
MMNLKYSALTALLLGITGMAQAQDYTSHLDKVLQAGQLAVCTTGDYKPYSLLREDGEYEGIDITMARSLAKSLGVNVQWV
PTTWKNLMPDMVAGKCDIGMGGISVSLERQKKAFFSNTLDVDGKIPLVRCADQALYQTVEQINQPSVRLIEPAGGTNEAF
ARAHLPKASLAFHDNKTIFQELLDKKADVMITDASEALYQQKRMPGLCAVNPTRYMQYGEKAYLLPRDDVAWKAYVDQWL
HLSKATGEYQQALSEWLAVPATP

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=237, Percent_Identity=27.0042194092827, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 29157; Mature: 29157

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNLKYSALTALLLGITGMAQAQDYTSHLDKVLQAGQLAVCTTGDYKPYSLLREDGEYEG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCC
IDITMARSLAKSLGVNVQWVPTTWKNLMPDMVAGKCDIGMGGISVSLERQKKAFFSNTLD
EEHHHHHHHHHHHCCCEEECCCCHHHHCHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCC
VDGKIPLVRCADQALYQTVEQINQPSVRLIEPAGGTNEAFARAHLPKASLAFHDNKTIFQ
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEECCCHHHHH
ELLDKKADVMITDASEALYQQKRMPGLCAVNPTRYMQYGEKAYLLPRDDVAWKAYVDQWL
HHHCCCCCEEEECHHHHHHHHHCCCCCEEECHHHHHHCCCEEEECCCCCCHHHHHHHHHH
HLSKATGEYQQALSEWLAVPATP
HHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMNLKYSALTALLLGITGMAQAQDYTSHLDKVLQAGQLAVCTTGDYKPYSLLREDGEYEG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCC
IDITMARSLAKSLGVNVQWVPTTWKNLMPDMVAGKCDIGMGGISVSLERQKKAFFSNTLD
EEHHHHHHHHHHHCCCEEECCCCHHHHCHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCC
VDGKIPLVRCADQALYQTVEQINQPSVRLIEPAGGTNEAFARAHLPKASLAFHDNKTIFQ
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEECCCHHHHH
ELLDKKADVMITDASEALYQQKRMPGLCAVNPTRYMQYGEKAYLLPRDDVAWKAYVDQWL
HHHCCCCCEEEECHHHHHHHHHCCCCCEEECHHHHHHCCCEEEECCCCCCHHHHHHHHHH
HLSKATGEYQQALSEWLAVPATP
HHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]