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The map label for this gene is ompR [H]

Identifier: 66044362

GI number: 66044362

Start: 1258918

End: 1259655

Strand: Direct

Name: ompR [H]

Synonym: Psyr_1111

Alternate gene names: 66044362

Gene position: 1258918-1259655 (Clockwise)

Preceding gene: 66044361

Following gene: 66044363

Centisome position: 20.66

GC content: 61.38

Gene sequence:

>738_bases
TTGAGCCCAGTCAGTAAATCGATCCTGTTGGTGGATGACGATCAGGAAATTCGCGAGTTGCTGGACACCTACCTGAGCCG
CGCCGGTTTCCAGGTGCGCACGGTGGGTGATGGCGCGGATTTCCGCCGGGCGTTCAATGACCAGCCAAGCGACCTGCTGA
TCCTTGACGTCATGCTGCCCGATGAAGACGGTTTCAGTCTGTGTCGCTGGATCCGCCAGCATCCGCGCCAGCCGCATGTG
CCGATCATCATGTTGACTGCCAGTTCTGACGAGGCCGACCGGGTCATCGGCCTGGAGCTGGGAGCCGATGATTATCTGGG
CAAGCCGTTCAGTCCGCGCGAGCTTCAGGCGCGCATCAAGGCGCTGTTGCGACGTGCCCAGTTCGGTCAGGAGCGTCCGG
GTGGCGATGTGATCCTGTTTGATGAGTGGCGACTGGACATGGTCAGCCACCGGCTGTTTCACAATGACGGCGAAGAGGTG
ATTCTGTCCGGCGCCGACTTCGCACTGCTCAAACTGTTTCTCGACAACCCCCAGCAGATTCTCGACCGCGACACCATCGG
CAACGCCACGCGTGGGCGAGAGCTGATGCCGCTGGAGCGGATCGTCGACATGGCGGTCAGCCGCCTGCGTCAGCGTCTGC
GCGACACCGGCAAGTCGCCGCGTCTGATCCGTACCATTCGTGGCAGTGGTTACCTGCTGGCCGCAAACGTCAACTCGCAA
GCGGGCAACGGCTATTAA

Upstream 100 bases:

>100_bases
TCATGGGGTCGGGCGTGGCCCTGCAACAGGCGTTTGGTGCGCAGATCTGAGCGATATGGCATAACAACAAGAATTCACAG
CCAGACAAGGACGCTTCAAC

Downstream 100 bases:

>100_bases
ACCGACAGCGGCAGGCGTGAAGAGAACCGGCCTGCCGCTGCCGCGCTCGTTGTTGGGCCGCATGTTGCTGCTGACCTTGC
TGGCGGTTTCGCTGGCTCAG

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSPVSKSILLVDDDQEIRELLDTYLSRAGFQVRTVGDGADFRRAFNDQPSDLLILDVMLPDEDGFSLCRWIRQHPRQPHV
PIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERPGGDVILFDEWRLDMVSHRLFHNDGEEV
ILSGADFALLKLFLDNPQQILDRDTIGNATRGRELMPLERIVDMAVSRLRQRLRDTGKSPRLIRTIRGSGYLLAANVNSQ
AGNGY

Sequences:

>Translated_245_residues
MSPVSKSILLVDDDQEIRELLDTYLSRAGFQVRTVGDGADFRRAFNDQPSDLLILDVMLPDEDGFSLCRWIRQHPRQPHV
PIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERPGGDVILFDEWRLDMVSHRLFHNDGEEV
ILSGADFALLKLFLDNPQQILDRDTIGNATRGRELMPLERIVDMAVSRLRQRLRDTGKSPRLIRTIRGSGYLLAANVNSQ
AGNGY
>Mature_244_residues
SPVSKSILLVDDDQEIRELLDTYLSRAGFQVRTVGDGADFRRAFNDQPSDLLILDVMLPDEDGFSLCRWIRQHPRQPHVP
IIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIKALLRRAQFGQERPGGDVILFDEWRLDMVSHRLFHNDGEEVI
LSGADFALLKLFLDNPQQILDRDTIGNATRGRELMPLERIVDMAVSRLRQRLRDTGKSPRLIRTIRGSGYLLAANVNSQA
GNGY

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=42.5531914893617, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=34.1772151898734, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=39.0557939914163, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=36.7521367521368, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=35.3448275862069, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=35.7758620689655, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=36.2445414847162, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=36.6812227074236, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=35.0877192982456, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=31.1203319502075, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=35.6521739130435, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=32.1739130434783, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=35.4838709677419, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=29.0076335877863, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787487, Length=106, Percent_Identity=34.9056603773585, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27696; Mature: 27565

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVSKSILLVDDDQEIRELLDTYLSRAGFQVRTVGDGADFRRAFNDQPSDLLILDVMLP
CCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEEEEEC
DEDGFSLCRWIRQHPRQPHVPIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCHHCCCCCCHHHHHHHHH
ALLRRAQFGQERPGGDVILFDEWRLDMVSHRLFHNDGEEVILSGADFALLKLFLDNPQQI
HHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHH
LDRDTIGNATRGRELMPLERIVDMAVSRLRQRLRDTGKSPRLIRTIRGSGYLLAANVNSQ
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCC
AGNGY
CCCCC
>Mature Secondary Structure 
SPVSKSILLVDDDQEIRELLDTYLSRAGFQVRTVGDGADFRRAFNDQPSDLLILDVMLP
CCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEEEEEC
DEDGFSLCRWIRQHPRQPHVPIIMLTASSDEADRVIGLELGADDYLGKPFSPRELQARIK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCHHCCCCCCHHHHHHHHH
ALLRRAQFGQERPGGDVILFDEWRLDMVSHRLFHNDGEEVILSGADFALLKLFLDNPQQI
HHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHH
LDRDTIGNATRGRELMPLERIVDMAVSRLRQRLRDTGKSPRLIRTIRGSGYLLAANVNSQ
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCC
AGNGY
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]