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The map label for this gene is gap [H]

Identifier: 66044359

GI number: 66044359

Start: 1254858

End: 1255859

Strand: Reverse

Name: gap [H]

Synonym: Psyr_1108

Alternate gene names: 66044359

Gene position: 1255859-1254858 (Counterclockwise)

Preceding gene: 66044370

Following gene: 66044358

Centisome position: 20.61

GC content: 59.58

Gene sequence:

>1002_bases
ATGACTCTTCGTATCGCAATCAACGGTTTTGGCCGAATCGGCCGCAACGTCCTACGCGCACTGTATACCCAAGGCTACCG
TCAGGACCTGCAGGTCGTCGCCATCAACGATCTTGGCGACAGCGAAATGAACGCACACCTGCTGCGCTTCGACACCGTAC
ACGGCCCTTTCAGCGGCACGGTCGAGTGCGACAAGGACAGCCTGACCGTCAATGGTGACCGTATTTCGGTCAGTGCCATT
CGCAATCCGGCCGAGCTGCCGTGGAAAGCGCAGGACATAGACGTGGTGTTCGAATGCACCGGTCTGTTCACCAGCCGTGA
CAAGGCTGCCGCGCACCTCACCGCCGGCGCCCGCAAGGTGATTATCTCCGCGCCAGCCAGCGGTGCCGATGCCACCATCG
TCTATGGTGTCAACCACGACACGCTGCGCCAGTCGCACCAGATCATCTCCAGCGCCTCGTGCACCACCAACTGCCTGGCA
CCGGTCGCTCAAATACTGCATCGCGAGCTGGGTATCGAAAACGGTCTGATGACCACCATTCATGCCTACACCAACGACCA
GAACCTGATCGATGTCTATCACACCGATCCGTACCGCGCCCGCTCGGCCACGCAGTCGATGATCCCGAGCAAGACCGGCG
CTGCCGAAGCGGTAGGTCTGGTACTGCCGGAGCTGGCAGGCAAACTCACCGGCATGGCTGTGCGCGTACCGGTCATCAAC
GTTTCGCTGGTCGACCTGACCGTGACCCTGAAGCGCGAAACCACCGCCGATGAAGTCAACGCGCTGATGAAAGAAGCCAG
TCAGCACTCCAAAGTGCTCGGTTACAACTCATTGCCGCTGGTCTCCCACGACTTCAACCACAACCCGCTGTCGTCGATCT
TCGACGCCAACCACACCAAGGTCAGCGGCAAGCTGCTCAAGGTACTGTCGTGGTACGACAACGAATGGGCGTTTTCCAAT
CGCATGCTCGACAACTGCCTGGCACTGCATAACGCGCAGTAA

Upstream 100 bases:

>100_bases
AGTTGTAGATAAAACAAAATATTGCCACTAAAAAGGCTTGTTTTCTATTTCTATGAGAATAATCTTGTAATTCCAACAAC
AAATTCAGAAGGACGGCTGT

Downstream 100 bases:

>100_bases
AGGACAGACGTCCAGACAAGCGCCTGCTCTCATGCCCATGCACTGCGTGGGCATGCGGCTTCGGGCGTCCTCGCGCGGTC
TTGAGCGCGCCTCTGGCGGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQVVAINDLGDSEMNAHLLRFDTVHGPFSGTVECDKDSLTVNGDRISVSAI
RNPAELPWKAQDIDVVFECTGLFTSRDKAAAHLTAGARKVIISAPASGADATIVYGVNHDTLRQSHQIISSASCTTNCLA
PVAQILHRELGIENGLMTTIHAYTNDQNLIDVYHTDPYRARSATQSMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
VSLVDLTVTLKRETTADEVNALMKEASQHSKVLGYNSLPLVSHDFNHNPLSSIFDANHTKVSGKLLKVLSWYDNEWAFSN
RMLDNCLALHNAQ

Sequences:

>Translated_333_residues
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQVVAINDLGDSEMNAHLLRFDTVHGPFSGTVECDKDSLTVNGDRISVSAI
RNPAELPWKAQDIDVVFECTGLFTSRDKAAAHLTAGARKVIISAPASGADATIVYGVNHDTLRQSHQIISSASCTTNCLA
PVAQILHRELGIENGLMTTIHAYTNDQNLIDVYHTDPYRARSATQSMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
VSLVDLTVTLKRETTADEVNALMKEASQHSKVLGYNSLPLVSHDFNHNPLSSIFDANHTKVSGKLLKVLSWYDNEWAFSN
RMLDNCLALHNAQ
>Mature_332_residues
TLRIAINGFGRIGRNVLRALYTQGYRQDLQVVAINDLGDSEMNAHLLRFDTVHGPFSGTVECDKDSLTVNGDRISVSAIR
NPAELPWKAQDIDVVFECTGLFTSRDKAAAHLTAGARKVIISAPASGADATIVYGVNHDTLRQSHQIISSASCTTNCLAP
VAQILHRELGIENGLMTTIHAYTNDQNLIDVYHTDPYRARSATQSMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVINV
SLVDLTVTLKRETTADEVNALMKEASQHSKVLGYNSLPLVSHDFNHNPLSSIFDANHTKVSGKLLKVLSWYDNEWAFSNR
MLDNCLALHNAQ

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=45.2599388379205, Blast_Score=285, Evalue=5e-77,
Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=43.2926829268293, Blast_Score=255, Evalue=4e-68,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=50.7507507507508, Blast_Score=343, Evalue=7e-96,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=48.1707317073171, Blast_Score=301, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=45.619335347432, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=45.619335347432, Blast_Score=270, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=45.619335347432, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=45.619335347432, Blast_Score=261, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=47.7064220183486, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6321631, Length=327, Percent_Identity=46.177370030581, Blast_Score=292, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=46.4831804281346, Blast_Score=292, Evalue=5e-80,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=47.5460122699387, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=47.5460122699387, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=46.6257668711656, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=46.6257668711656, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=43.6923076923077, Blast_Score=261, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36259; Mature: 36127

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQVVAINDLGDSEMNAHLLRFDTVHGPFSGT
CEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCE
VECDKDSLTVNGDRISVSAIRNPAELPWKAQDIDVVFECTGLFTSRDKAAAHLTAGARKV
EEECCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEE
IISAPASGADATIVYGVNHDTLRQSHQIISSASCTTNCLAPVAQILHRELGIENGLMTTI
EEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQNLIDVYHTDPYRARSATQSMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
EEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEE
VSLVDLTVTLKRETTADEVNALMKEASQHSKVLGYNSLPLVSHDFNHNPLSSIFDANHTK
EEEEEEEEEEECCCCHHHHHHHHHHHHHHCEEECCCCCCCEECCCCCCCHHHHHCCCCCC
VSGKLLKVLSWYDNEWAFSNRMLDNCLALHNAQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLRIAINGFGRIGRNVLRALYTQGYRQDLQVVAINDLGDSEMNAHLLRFDTVHGPFSGT
EEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCE
VECDKDSLTVNGDRISVSAIRNPAELPWKAQDIDVVFECTGLFTSRDKAAAHLTAGARKV
EEECCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEE
IISAPASGADATIVYGVNHDTLRQSHQIISSASCTTNCLAPVAQILHRELGIENGLMTTI
EEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQNLIDVYHTDPYRARSATQSMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
EEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEE
VSLVDLTVTLKRETTADEVNALMKEASQHSKVLGYNSLPLVSHDFNHNPLSSIFDANHTK
EEEEEEEEEEECCCCHHHHHHHHHHHHHHCEEECCCCCCCEECCCCCCCHHHHHCCCCCC
VSGKLLKVLSWYDNEWAFSNRMLDNCLALHNAQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]