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The map label for this gene is hupA [H]

Identifier: 66044337

GI number: 66044337

Start: 1225706

End: 1225987

Strand: Direct

Name: hupA [H]

Synonym: Psyr_1084

Alternate gene names: 66044337

Gene position: 1225706-1225987 (Clockwise)

Preceding gene: 66044334

Following gene: 66044343

Centisome position: 20.11

GC content: 51.42

Gene sequence:

>282_bases
ATGGCTCTTACTAAAGACCAATTGATCGCCGATATCGCTGAAGCTATCGACGCGCCAAAAACCACCGCGCGTAGTGCTCT
TGAGCAACTGGGCCACATTGTTGCCGACCAATTGGAAAAAGGCGTGGAAATCACTTTGCCAAATATCGGCAAACTGAAGG
TTGCAGAGCGTCCTGCTCGCACTGGCCGCAACCCTTCGACTGGCGCTGCCATCGAAATCGCTGCCAAGAAAGTTATCAAG
TTCGTACCAGCCAAAGTGCTGACCGACTCGATCAACAAGTAA

Upstream 100 bases:

>100_bases
TTAATCGTGGCTGCTAGCGGGTGGCCAGGTTCGTTGCCTGGCCACGGGCCGACGTTGCGCTCTGCAATCCAAATGAATTT
GATAGGGAAGGAACACCACC

Downstream 100 bases:

>100_bases
GCAACCGCTTGCTGTGAAAAAGCCGTGCACCGGTTAACCGGGCACGGCTTTTTTGTGGGCGCCTGATTGGACACCTCCCG
CAAAGTCGGACGCAGAGCGT

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MALTKDQLIADIAEAIDAPKTTARSALEQLGHIVADQLEKGVEITLPNIGKLKVAERPARTGRNPSTGAAIEIAAKKVIK
FVPAKVLTDSINK

Sequences:

>Translated_93_residues
MALTKDQLIADIAEAIDAPKTTARSALEQLGHIVADQLEKGVEITLPNIGKLKVAERPARTGRNPSTGAAIEIAAKKVIK
FVPAKVLTDSINK
>Mature_92_residues
ALTKDQLIADIAEAIDAPKTTARSALEQLGHIVADQLEKGVEITLPNIGKLKVAERPARTGRNPSTGAAIEIAAKKVIKF
VPAKVLTDSINK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=43.3333333333333, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=42.6966292134831, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9855; Mature: 9723

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKDQLIADIAEAIDAPKTTARSALEQLGHIVADQLEKGVEITLPNIGKLKVAERPAR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHH
TGRNPSTGAAIEIAAKKVIKFVPAKVLTDSINK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALTKDQLIADIAEAIDAPKTTARSALEQLGHIVADQLEKGVEITLPNIGKLKVAERPAR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHH
TGRNPSTGAAIEIAAKKVIKFVPAKVLTDSINK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1508695 [H]