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The map label for this gene is cscR [H]

Identifier: 66044012

GI number: 66044012

Start: 862009

End: 863001

Strand: Reverse

Name: cscR [H]

Synonym: Psyr_0757

Alternate gene names: 66044012

Gene position: 863001-862009 (Counterclockwise)

Preceding gene: 66044013

Following gene: 66044010

Centisome position: 14.16

GC content: 59.11

Gene sequence:

>993_bases
ATGACCTCAGTTAAAGACGTTGCAAAACTGGCCGGTGTGTCTCTGATGACGGTGTCTCGGGCGCTCAATGATCCGGGAAA
GCTGAGCCCGGAGACTTATCAGCGAGTGCGCAACGCGATCGATGAGCTTCAATTCGTACCCAGCCTGTCGGCTCGCCGGA
TACGCGGCGACAACCTGCAGACCCGGACCATCGGCGTATTCGCCCTGGACACCGCAACGACGCCTTTTGCGGTCGAGCTG
CTGCTGTCCATCGAACAGACCGCGCAGCAGGCAGGCTGGAACGTATTTATCCTCAACCTGCTGAGTAACCCGCCCACCGA
CCAGAACATTGACCTGATGCTCTCACATCGCCCAGACGGGTTGATCTTCAGCGCCATGGGCTTGCGCAAAGTGAGTATCC
CGCAGCGCTTGAAGAGCAAACCGCTGGTGCTCGCCAACTGCGTAGCCGATGACAGCAGCCTTGTCAGTTATGTGCCGGAC
GACGAAATGGGTCAGTACCGTGCCTTGCACCACGCGTTCAGCAAGGGCTATCGACGCCCGCTGTTCATCAACCTGCCAAA
ACAGAGCCTGGCCTGGGAAATCCGCCAGGCGGGTATGCAGCGTGCCTGCGAGGCATTCGGTCTGGCTCGCGACGAACTCT
TGCAATACAACCTGTCCGAACACGACGCCTATTGGGAAACCGCCGCCATCCTCGCCCGGCATATGCTGGATGGCCGTCCA
CAGTTCGACATTCTGATCTGCGGCAATGACCGCATTGCCTTTTGTGCCTACCAGCTGCTGCTCGGCCAGGGCCTGAAAAT
CCCCGGCGATGTCGCCGTACTGGGTTATGACAACATGATCGGCATCGCCGAGCTTTTCATCCCTGCGCTGACCACGGTGC
AACTGCCGTATTACGAGATCGGTCGCAACGCCGCCCGGCACTTGATCGACAGCATTGAAGTGTCGGGCTCCCAGCCTGTG
GACTGCCCGCTGGTGGTCAGAGAATCGTTATGA

Upstream 100 bases:

>100_bases
TCTCCTCCGGATACCTGTAAGGTAAATCATTGAAGTCGCGAAAAAAATCAGCTCTCTGTAGCATGATAATCATCAGTCAA
CCCGACAGGCCCCGACCCGC

Downstream 100 bases:

>100_bases
AGCCTTGCGCGAGATAGCCCACGCATCGAGTCGTCACGCGGGACGAGCCCAATAAAAGCGTCGGCTCTTGAGTTCTGATT
TTCAACTTCGAAACGCTGGC

Product: LacI transcriptional regulator

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTSVKDVAKLAGVSLMTVSRALNDPGKLSPETYQRVRNAIDELQFVPSLSARRIRGDNLQTRTIGVFALDTATTPFAVEL
LLSIEQTAQQAGWNVFILNLLSNPPTDQNIDLMLSHRPDGLIFSAMGLRKVSIPQRLKSKPLVLANCVADDSSLVSYVPD
DEMGQYRALHHAFSKGYRRPLFINLPKQSLAWEIRQAGMQRACEAFGLARDELLQYNLSEHDAYWETAAILARHMLDGRP
QFDILICGNDRIAFCAYQLLLGQGLKIPGDVAVLGYDNMIGIAELFIPALTTVQLPYYEIGRNAARHLIDSIEVSGSQPV
DCPLVVRESL

Sequences:

>Translated_330_residues
MTSVKDVAKLAGVSLMTVSRALNDPGKLSPETYQRVRNAIDELQFVPSLSARRIRGDNLQTRTIGVFALDTATTPFAVEL
LLSIEQTAQQAGWNVFILNLLSNPPTDQNIDLMLSHRPDGLIFSAMGLRKVSIPQRLKSKPLVLANCVADDSSLVSYVPD
DEMGQYRALHHAFSKGYRRPLFINLPKQSLAWEIRQAGMQRACEAFGLARDELLQYNLSEHDAYWETAAILARHMLDGRP
QFDILICGNDRIAFCAYQLLLGQGLKIPGDVAVLGYDNMIGIAELFIPALTTVQLPYYEIGRNAARHLIDSIEVSGSQPV
DCPLVVRESL
>Mature_329_residues
TSVKDVAKLAGVSLMTVSRALNDPGKLSPETYQRVRNAIDELQFVPSLSARRIRGDNLQTRTIGVFALDTATTPFAVELL
LSIEQTAQQAGWNVFILNLLSNPPTDQNIDLMLSHRPDGLIFSAMGLRKVSIPQRLKSKPLVLANCVADDSSLVSYVPDD
EMGQYRALHHAFSKGYRRPLFINLPKQSLAWEIRQAGMQRACEAFGLARDELLQYNLSEHDAYWETAAILARHMLDGRPQ
FDILICGNDRIAFCAYQLLLGQGLKIPGDVAVLGYDNMIGIAELFIPALTTVQLPYYEIGRNAARHLIDSIEVSGSQPVD
CPLVVRESL

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=335, Percent_Identity=31.3432835820896, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=30.5031446540881, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787948, Length=325, Percent_Identity=28.3076923076923, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=28.7625418060201, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789068, Length=339, Percent_Identity=28.023598820059, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787580, Length=326, Percent_Identity=27.9141104294479, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=24.3478260869565, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=26.4615384615385, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=28.1481481481481, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790689, Length=313, Percent_Identity=24.9201277955272, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36580; Mature: 36448

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVKDVAKLAGVSLMTVSRALNDPGKLSPETYQRVRNAIDELQFVPSLSARRIRGDNLQ
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCE
TRTIGVFALDTATTPFAVELLLSIEQTAQQAGWNVFILNLLSNPPTDQNIDLMLSHRPDG
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCC
LIFSAMGLRKVSIPQRLKSKPLVLANCVADDSSLVSYVPDDEMGQYRALHHAFSKGYRRP
EEEECCCCEECCCHHHHCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCC
LFINLPKQSLAWEIRQAGMQRACEAFGLARDELLQYNLSEHDAYWETAAILARHMLDGRP
EEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
QFDILICGNDRIAFCAYQLLLGQGLKIPGDVAVLGYDNMIGIAELFIPALTTVQLPYYEI
CEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHEECCHHHH
GRNAARHLIDSIEVSGSQPVDCPLVVRESL
HHHHHHHHHHHHHCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
TSVKDVAKLAGVSLMTVSRALNDPGKLSPETYQRVRNAIDELQFVPSLSARRIRGDNLQ
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCE
TRTIGVFALDTATTPFAVELLLSIEQTAQQAGWNVFILNLLSNPPTDQNIDLMLSHRPDG
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCC
LIFSAMGLRKVSIPQRLKSKPLVLANCVADDSSLVSYVPDDEMGQYRALHHAFSKGYRRP
EEEECCCCEECCCHHHHCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCC
LFINLPKQSLAWEIRQAGMQRACEAFGLARDELLQYNLSEHDAYWETAAILARHMLDGRP
EEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
QFDILICGNDRIAFCAYQLLLGQGLKIPGDVAVLGYDNMIGIAELFIPALTTVQLPYYEI
CEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHEECCHHHH
GRNAARHLIDSIEVSGSQPVDCPLVVRESL
HHHHHHHHHHHHHCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA