Click here to switch to the map view.

The map label for this gene is argS

Identifier: 66043664

GI number: 66043664

Start: 423674

End: 425413

Strand: Reverse

Name: argS

Synonym: Psyr_0397

Alternate gene names: 66043664

Gene position: 425413-423674 (Counterclockwise)

Preceding gene: 66043665

Following gene: 66043663

Centisome position: 6.98

GC content: 61.21

Gene sequence:

>1740_bases
ATGAAAGACACGATTCGCCAGCTGATTCAACAAGCCCTGACCCGTCTCGTCACCGAGGGCGTCTTGCCAGAAGGGCTGAC
GCCGGCGATTCAGGTGGAAAACGCCCGCGACAAGACGCACGGCGACTTCGCCAGCAATATCGCGATGATGCTCGCCAAGC
CTGCCGGCATGAAACCGCGCGATCTGGCTGAAAAACTGATCGCCGCACTCCCGGCCGACCAGCAAATCAGCAAGGTCGAA
ATTGCCGGGCCGGGCTTCCTGAACTTCTTCCAGAACACCGCCGCGCTGGCCGCACGCCTCGACGCTGCCTTGGCCGACCC
GGAAAAACTGTCGGTCCGCAAGGCGGGCGCTGCACAGCGCGTGGTCGTCGATCTGTCGGCACCCAATCTGGCCAAGGAAA
TGCACGTTGGGCACCTGCGCTCGACCATTATTGGCGACGGCGTGGCGAACGTTCTCGAGTTTCTCGGTGACACGGTCATT
CGCCAGAACCACGTGGGCGACTGGGGCACCCAGTTCGGCATGCTGCTGGCCTATCTGCAGGAAAAGCCGGCGACCAGCGA
CGAACTGTCCGACCTGGAAAACTTCTACCGCGCCGCCAAGCAGCGCTTTGACGAGTCCGAAGAGTTCGCCGAGCGTGCCC
GTGGTCTGGTGGTCAAGCTGCAGGCCGGCGATGCCGAATGCCTGGCGCTGTGGACGCGCTTCAAGGATATCTCGCTGTCG
CACTGTCAGGAGACCTACGAGCGCCTCAACGTCAAGCTGACCCCGGCCGACGTGATGGGCGAAAGCGCCTATAACGATGA
CCTGGCCAATGTCGTCAACGACCTGAAAGCCACGGGCCTGCTGGTCGAGAGCAATGGCGCACAATGCGTGTTCCTCGAAG
AATTCCGCACCGCCGATGACACGCCGTTGCCGGTCATCGTGCAGAAGGCCGGTGGTGGTTATCTGTATGCCACCACCGAC
CTGGCAGCGATCCGCTATCGCAGCAAGGTGCTCAAGGCCGATCGCGTACTGTATTTCGTCGACCAGCGTCAGGCCCTGCA
CTTCCAGCAGGTGTTCGAAGTGGCGCGCCGCGCCGGTTTCGTGCATGACGGCATGCAGCTCGAACACATGGGCTTCGGCA
CCATGAACGGCGCCGACGGCCGCCCGTTCAAGACCCGTGATGGCGGTACGGTCAAGCTCATCGACCTGCTTGATGAAGCC
GAAGAACGTGCCTACACGCTGGTCAGGGAAAAGAACCCGGAAGTCGCCGAAGCGGAATTGCGCAGCATTGCCAAGGCCGT
GGGCATCAGTGCGGTGAAATACGCCGACCTGTCCAAGCACCGCGCCAGCGATTACAGCTTCAACTTCGATCAGATGCTCA
GTTTCGAAGGCAACACCGCGCCCTATCTGCTGTACGCCTACACCCGTGTGGCGGGCGTGTTCCGCAAGCTGGGCAGCGCG
TTTGACGCCAGCAAGGGCCAGATCGTCCTCGCAGCGCCGCAGGAACAGGAACTGGCCGCACGTCTGGCGCAGTTCACCGA
AACACTGAACAACGTCGCAGAAAAAGGCACACCGCACGTACTTTGTGCTTACCTGTATGACCTTGCGGGTCTGTTTTCGA
GCTTTTACGAAAACTGCCCGATCCTTGGTGCGGAAAACCCCGATCAGCAACAGAGCCGTCTGCGCCTGGCTGCACTGACC
GGCCGCACCCTCAAGCAAGGCCTGGACCTGTTGGGTCTGGAAACTCTGGAGCGTATGTAA

Upstream 100 bases:

>100_bases
TAAGTCACGCCGTTGGCAAGCAGGCTTGAGCAACGGATAATGCAGAGTTTTTCCACCCGCGCATCGAAGCGCCACCGCGC
TTGCGGTCGAAGAGAGCACC

Downstream 100 bases:

>100_bases
GTTGGCAGTTGCGAAGAAGAAACCGGCACCCAAGCGGGGCGCCAGCCGTTACCAGGCACCCGCGAAGAAGCCGATTCCAG
GATGGTTGTGGCTGGCGATT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPRDLAEKLIAALPADQQISKVE
IAGPGFLNFFQNTAALAARLDAALADPEKLSVRKAGAAQRVVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLEFLGDTVI
RQNHVGDWGTQFGMLLAYLQEKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLS
HCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADDTPLPVIVQKAGGGYLYATTD
LAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGFVHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEA
EERAYTLVREKNPEVAEAELRSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGSA
FDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCPILGAENPDQQQSRLRLAALT
GRTLKQGLDLLGLETLERM

Sequences:

>Translated_579_residues
MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPRDLAEKLIAALPADQQISKVE
IAGPGFLNFFQNTAALAARLDAALADPEKLSVRKAGAAQRVVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLEFLGDTVI
RQNHVGDWGTQFGMLLAYLQEKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLS
HCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADDTPLPVIVQKAGGGYLYATTD
LAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGFVHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEA
EERAYTLVREKNPEVAEAELRSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGSA
FDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCPILGAENPDQQQSRLRLAALT
GRTLKQGLDLLGLETLERM
>Mature_579_residues
MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPRDLAEKLIAALPADQQISKVE
IAGPGFLNFFQNTAALAARLDAALADPEKLSVRKAGAAQRVVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLEFLGDTVI
RQNHVGDWGTQFGMLLAYLQEKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLS
HCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADDTPLPVIVQKAGGGYLYATTD
LAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGFVHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEA
EERAYTLVREKNPEVAEAELRSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGSA
FDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCPILGAENPDQQQSRLRLAALT
GRTLKQGLDLLGLETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=584, Percent_Identity=36.986301369863, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI197100773, Length=595, Percent_Identity=29.4117647058824, Blast_Score=215, Evalue=7e-56,
Organism=Escherichia coli, GI1788184, Length=580, Percent_Identity=56.2068965517241, Blast_Score=620, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI71985061, Length=593, Percent_Identity=38.1112984822934, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71985068, Length=553, Percent_Identity=39.0596745027125, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17532153, Length=391, Percent_Identity=28.9002557544757, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=596, Percent_Identity=32.3825503355705, Blast_Score=264, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6321883, Length=600, Percent_Identity=30, Blast_Score=240, Evalue=4e-64,
Organism=Drosophila melanogaster, GI18859963, Length=579, Percent_Identity=37.3056994818653, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI28571570, Length=480, Percent_Identity=31.6666666666667, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PSEU2 (Q4ZZF5)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_233505.1
- ProteinModelPortal:   Q4ZZF5
- SMR:   Q4ZZF5
- STRING:   Q4ZZF5
- GeneID:   3365873
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_0397
- NMPDR:   fig|205918.4.peg.730
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- BioCyc:   PSYR205918:PSYR_0397-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63676; Mature: 63676

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHH
DLAEKLIAALPADQQISKVEIAGPGFLNFFQNTAALAARLDAALADPEKLSVRKAGAAQR
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
VVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLEFLGDTVIRQNHVGDWGTQFGMLLAYLQ
EEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLS
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHH
HCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADD
HHHHHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEHHHCCCCC
TPLPVIVQKAGGGYLYATTDLAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGF
CCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHCCC
VHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEAEERAYTLVREKNPEVAEAEL
CCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGSA
HHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
FDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCP
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
ILGAENPDQQQSRLRLAALTGRTLKQGLDLLGLETLERM
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHH
DLAEKLIAALPADQQISKVEIAGPGFLNFFQNTAALAARLDAALADPEKLSVRKAGAAQR
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
VVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLEFLGDTVIRQNHVGDWGTQFGMLLAYLQ
EEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLS
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHH
HCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADD
HHHHHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEHHHCCCCC
TPLPVIVQKAGGGYLYATTDLAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGF
CCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHCCC
VHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEAEERAYTLVREKNPEVAEAEL
CCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGSA
HHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
FDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCP
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
ILGAENPDQQQSRLRLAALTGRTLKQGLDLLGLETLERM
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA