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The map label for this gene is dtd [H]

Identifier: 66043643

GI number: 66043643

Start: 401354

End: 401791

Strand: Direct

Name: dtd [H]

Synonym: Psyr_0376

Alternate gene names: 66043643

Gene position: 401354-401791 (Clockwise)

Preceding gene: 66043642

Following gene: 66043644

Centisome position: 6.59

GC content: 57.53

Gene sequence:

>438_bases
ATGAAAGGTTTGTTGCAGCGCGTGCGAAGTGCGCGCGTCGAGGTGGGCACCGAGGTCGTGGGCGCCATTGAACAGGGCAT
ATTGGTGTTGGTGGGAATAGAGCCTCAAGACACCCGCGCCAGTGCCGATAAGTTGCTGCACAAGTTGCTCAATTATCGAG
TGTTCAGCGATGTTGAGGGCAAGATGAATCTGTCCTTGCGTGAGGTGGGGGGCGGCCTGTTGCTGGTTTCCCAGTTCACG
CTGGCTGCGGACACCAAAAGCGGGTTGCGTGCGGGCTTCTCGAAAGCCGCGCCTCCAGCACTGGGCGCCGAGCTGTTCGA
CTATCTGTTGAGCCAGGCCAGAATCGCGCATCCCACGGTAGCTGCGGGCCAGTTTGGTGCAGACATGCAGGTGCACCTGA
TAAATGATGGCCCCGTGACATTTTTGTTTGATACATAA

Upstream 100 bases:

>100_bases
GGTGCGTGCTGCCGCAGAAGTGGCGCGCAATCTGCTCGACCTGCCGCCCGAAGAGGCGTGACAGCAGTCCGGTATTGGTT
TTGAGTCTGGAAAGGCATCT

Downstream 100 bases:

>100_bases
GCTACGATTTCACTTTATCTCCCTGAATTCATCTGTCTTGCGGGAATAAATTTCTTTGTCATACCTGATGCGTTGTGGCG
CGCGCTACTGGATAATCGCG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEGKMNLSLREVGGGLLLVSQFT
LAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTVAAGQFGADMQVHLINDGPVTFLFDT

Sequences:

>Translated_145_residues
MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEGKMNLSLREVGGGLLLVSQFT
LAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTVAAGQFGADMQVHLINDGPVTFLFDT
>Mature_145_residues
MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEGKMNLSLREVGGGLLLVSQFT
LAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTVAAGQFGADMQVHLINDGPVTFLFDT

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=40.5405405405405, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=50.3496503496504, Blast_Score=150, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.1891891891892, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=38.5135135135135, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=36.0544217687075, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15475; Mature: 15475

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEG
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCC
KMNLSLREVGGGLLLVSQFTLAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTV
CCCEEHHHHCCCEEEEEHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
AAGQFGADMQVHLINDGPVTFLFDT
CCCCCCCCEEEEEECCCCEEEEECC
>Mature Secondary Structure
MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEG
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCC
KMNLSLREVGGGLLLVSQFTLAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTV
CCCEEHHHHCCCEEEEEHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
AAGQFGADMQVHLINDGPVTFLFDT
CCCCCCCCEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA