Click here to switch to the map view.

The map label for this gene is pip [H]

Identifier: 66043642

GI number: 66043642

Start: 400343

End: 401314

Strand: Direct

Name: pip [H]

Synonym: Psyr_0375

Alternate gene names: 66043642

Gene position: 400343-401314 (Clockwise)

Preceding gene: 66043636

Following gene: 66043643

Centisome position: 6.57

GC content: 61.32

Gene sequence:

>972_bases
ATGCAGACTTTGTACCCGCAGATCAAACCCTACGCCCGGCACGATCTGGCCGTGGAACAACCGCATGTGCTTTACGTCGA
TGAGAGTGGCTCGCCAGAAGGCTTGCCGGTGGTGTTTATCCACGGCGGGCCGGGTTCGGGATGCGATGCGCACAGTCGCT
GCTATTTCGATCCCAACCTGTACCGCATTGTCACGTTCGACCAGCGCGGCTGCGGTCGTTCCACACCGCATGCCAGCCTT
GAAAACAACACCACCTGGAAACTGGTGGAAGACCTTGAAGCGATTCGCGAGCACCTCGGGATCGACAAATGGGTGTTGTT
CGGCGGTTCGTGGGGTTCGACCCTCGCTCTGGCCTATGCACAGACCCATCCCGACCGCGTGCACGCGATGATCCTGCGTG
GCGTATTCCTTGCCCGTCAGCAGGAAATCGACTGGTTCTATCAGGCCGGCGCCAGCCGTCTGTTTCCGGACTATTGGCAG
GATTATGTCGCGCCGATCCCGCTGGACGAGCGTGACAACATTCTGGCTGCCTTCCACAAGCGACTCACCGGTCCGGACCA
GATCGCCCAGATGCACGCTGCCAAGGCCTGGTCGACCTGGGAAGGGCGCTGCGCAACCCTGCGGCCCAATCCGCAAGTGG
TCGATCGCTTTGCCGAGCCGCACCGCGCGTTGTCCATCGCGCGCATCGAATGTCACTACTTCATGAACAACGCCTTTCTG
GAAGACAACCAGCTGATTCGCGACATGCCGAAGATCGCGCACCTGCCGGCAATCATCGTCCACGGTCGTTACGATGTCAT
CTGTCCGCTGGATAATGCATGGGAGCTGCACCAGAACTGGCCTGGCAGTGAACTGCAGGTGATTCGCGAGGCCGGGCATT
CGGCAGCCGAGCCGGGTATCGCCGACGCGCTGGTGCGTGCTGCCGCAGAAGTGGCGCGCAATCTGCTCGACCTGCCGCCC
GAAGAGGCGTGA

Upstream 100 bases:

>100_bases
TCCTGATCAATGACGTGCAGCATGCTGATTCTTCGTTTCGGGTTTATGATGCCCCACGGCAGAATAATAGAAGCCTCTGA
ACTGGACTTATGGAGCACTT

Downstream 100 bases:

>100_bases
CAGCAGTCCGGTATTGGTTTTGAGTCTGGAAAGGCATCTATGAAAGGTTTGTTGCAGCGCGTGCGAAGTGCGCGCGTCGA
GGTGGGCACCGAGGTCGTGG

Product: peptidase S33, proline iminopeptidase 1

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQTLYPQIKPYARHDLAVEQPHVLYVDESGSPEGLPVVFIHGGPGSGCDAHSRCYFDPNLYRIVTFDQRGCGRSTPHASL
ENNTTWKLVEDLEAIREHLGIDKWVLFGGSWGSTLALAYAQTHPDRVHAMILRGVFLARQQEIDWFYQAGASRLFPDYWQ
DYVAPIPLDERDNILAAFHKRLTGPDQIAQMHAAKAWSTWEGRCATLRPNPQVVDRFAEPHRALSIARIECHYFMNNAFL
EDNQLIRDMPKIAHLPAIIVHGRYDVICPLDNAWELHQNWPGSELQVIREAGHSAAEPGIADALVRAAAEVARNLLDLPP
EEA

Sequences:

>Translated_323_residues
MQTLYPQIKPYARHDLAVEQPHVLYVDESGSPEGLPVVFIHGGPGSGCDAHSRCYFDPNLYRIVTFDQRGCGRSTPHASL
ENNTTWKLVEDLEAIREHLGIDKWVLFGGSWGSTLALAYAQTHPDRVHAMILRGVFLARQQEIDWFYQAGASRLFPDYWQ
DYVAPIPLDERDNILAAFHKRLTGPDQIAQMHAAKAWSTWEGRCATLRPNPQVVDRFAEPHRALSIARIECHYFMNNAFL
EDNQLIRDMPKIAHLPAIIVHGRYDVICPLDNAWELHQNWPGSELQVIREAGHSAAEPGIADALVRAAAEVARNLLDLPP
EEA
>Mature_323_residues
MQTLYPQIKPYARHDLAVEQPHVLYVDESGSPEGLPVVFIHGGPGSGCDAHSRCYFDPNLYRIVTFDQRGCGRSTPHASL
ENNTTWKLVEDLEAIREHLGIDKWVLFGGSWGSTLALAYAQTHPDRVHAMILRGVFLARQQEIDWFYQAGASRLFPDYWQ
DYVAPIPLDERDNILAAFHKRLTGPDQIAQMHAAKAWSTWEGRCATLRPNPQVVDRFAEPHRALSIARIECHYFMNNAFL
EDNQLIRDMPKIAHLPAIIVHGRYDVICPLDNAWELHQNWPGSELQVIREAGHSAAEPGIADALVRAAAEVARNLLDLPP
EEA

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36436; Mature: 36436

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLYPQIKPYARHDLAVEQPHVLYVDESGSPEGLPVVFIHGGPGSGCDAHSRCYFDPNL
CCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEECCCE
YRIVTFDQRGCGRSTPHASLENNTTWKLVEDLEAIREHLGIDKWVLFGGSWGSTLALAYA
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEH
QTHPDRVHAMILRGVFLARQQEIDWFYQAGASRLFPDYWQDYVAPIPLDERDNILAAFHK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCCCCCCCCCCHHHHHHH
RLTGPDQIAQMHAAKAWSTWEGRCATLRPNPQVVDRFAEPHRALSIARIECHYFMNNAFL
HCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCHHHHEEEEEEEEEEECCCCEE
EDNQLIRDMPKIAHLPAIIVHGRYDVICPLDNAWELHQNWPGSELQVIREAGHSAAEPGI
CCCHHHHHHHHHHHCCEEEEECCEEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCH
ADALVRAAAEVARNLLDLPPEEA
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTLYPQIKPYARHDLAVEQPHVLYVDESGSPEGLPVVFIHGGPGSGCDAHSRCYFDPNL
CCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEECCCE
YRIVTFDQRGCGRSTPHASLENNTTWKLVEDLEAIREHLGIDKWVLFGGSWGSTLALAYA
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEH
QTHPDRVHAMILRGVFLARQQEIDWFYQAGASRLFPDYWQDYVAPIPLDERDNILAAFHK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCCCCCCCCCCHHHHHHH
RLTGPDQIAQMHAAKAWSTWEGRCATLRPNPQVVDRFAEPHRALSIARIECHYFMNNAFL
HCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCHHHHEEEEEEEEEEECCCCEE
EDNQLIRDMPKIAHLPAIIVHGRYDVICPLDNAWELHQNWPGSELQVIREAGHSAAEPGI
CCCHHHHHHHHHHHCCEEEEECCEEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCH
ADALVRAAAEVARNLLDLPPEEA
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]